Integrated Risk Information System (IRIS)

IRIS (Integrated Risk Information System) is a compilation of electronic reports on specific substances found in the environment and their potential to cause human health effects. IRIS was initially developed for EPA staff in response to a growing demand for consistent information on substances for use in risk assessments, decision-making and regulatory activities. The information in IRIS is intended for those without extensive training in toxicology, but with some knowledge of health sciences.

Getting Started with IRIS

An overview of the web site What is IRIS? How does EPA decide which substances to add or update? More frequent questions >>

Using the IRIS Database

IRIS Process (2009 Update) Advanced Search in IRIS Compare IRIS Values Download IRIS

New Assessments and Reviews

The following documents are new assessments or under external peer review at this time: More Recent Additions >> Substance Milestone Meeting/Release date Final Assessments Thallium (I), soluble salts New Tox Review & Summary 09/30/2009 Thallium oxide Updated Tox Review & Summary 09/30/2009 Thallium selenite Updated Tox Review & Summary 09/30/2009 Bromobenzene New Tox Review & Summary 09/30/2009 1,2,3-Trichloropropane Updated Tox Review & Summary Interagency Comments 09/30/2009 10/14/2009 Cerium Oxide and Cerium Compounds New Tox Review & Summary Interagency Comments 09/29/2009 10/14/2009 2-Hexanone New Tox Review & Summary Interagency Comments 09/25/2009 10/14/2009 Chlordecone (Kepone) New Tox Review & Summary Interagency Comments 09/22/2009 10/14/2009 Draft Assessments Chloroprene External Peer Review Draft Listening Session 09/29/2009 11/23/2009 Trichloroacetic Acid External Peer Review Draft Interagency Comments Listening Session External Peer Review Meeting 09/24/2009 10/14/2009 11/04/2009 12/10/2009 Cis-and Trans-1,2-Dichloroethylene External Peer Review Draft Interagency Comments Listening Session External Peer Review Meeting 09/24/2009 10/14/2009 10/19/2009 12/17/2009 1,1,2,2-Tetrachloroethane External Peer Review Draft Listening Session 09/24/2009 10/14/2009 Hydrogen Cyanide and Cyanide Salts External Peer Review Draft Listening Session External Peer Review Meeting 09/23/2009 10/27/2009 12/14/2009 Ethyl Tertiary Butyl Ether Listening Session 10/07/2009 Trichloroethylene External Peer Review Draft 11/03/2009