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Recent Additions

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Find notifications (by year) of new IRIS Summary and Toxicological Review postings to IRIS, Federal Register notices, peer review meetings and other announcements about the IRIS Program and Web site. If you like to receive notifications of Recent Addition items, please contact us.

18 November 2011

A new Summary for Dichloromethane and a new accompanying Toxicological Review (PDF) (567 pp, 5.10M) have been added to the IRIS Web site. The Interagency Science Discussion Draft of the Dichloromethane IRIS assessment has also been released.

18 November 2011

Notice: Request for Nominations of Candidates to the EPA's Science Advisory Board (SAB) Chemical Assessment Advisory Committee for advice on the review of IRIS Toxicological Reviews, Federal Register Nov 18, 2011

The SAB Staff Office is seeking nominations of experts to serve on the SAB Chemical Assessment Advisory Committee to provide advice regarding Toxicological Reviews of environmental chemicals available on EPA's Integrated Risk Information System (IRIS). Candidates should have knowledge in human health risk assessment and expertise in a range of disciplines including, but not limited to: public health; epidemiology; toxicology; modeling; biostatistics; and risk assessment. Members of the SAB and its subcommittees constitute a distinguished body of non-EPA scientists, engineers, economists, and social scientists that are nationally and internationally-recognized experts in their respective fields from academia, industry, state, and Tribal governments, research institutes, and non-governmental organizations. Members of SAB committees are appointed by the EPA Administrator for a period of three years. The deadline for nominations closes Jan 6, 2012.

17 November 2011

Notice: IRIS Toxicological Review of n-Butanol (External Review Draft) Extension of Public Comment Period
EPA has announced that they have reopened the public comment period for the review of the IRIS Toxicological Review of n-Butanol (External Review Draft) (originally announced in an August 31, 2011 Federal Register Notice) until December 7, 2011. [Federal Register Notice Nov 16, 2011]

14 November 2011

Notice: IRIS Toxicological Review of Vanadium Pentoxide (External Review Draft) Extension of Public Comment Period & Listening Session Announcement
EPA has announced an extension of the public comment period for the review of the IRIS Toxicological Review of Vanadium Pentoxide (External Review Draft) (originally announced in a September 30, 2011 Federal Register Notice) to December 29, 2011. In addition, EPA has rescheduled the listening session to December 8, 2011. [Federal Register Notice Nov 9, 2011]

26 October 2011

Notice: External Peer Review Comments available on the Toxicological Review of Methanol (non-cancer)
On July 22, 2011, an external peer review panel meeting was hosted by an independent contractor on the draft Toxicological Review of Methanol (non-cancer): In Support of the Summary Information in the Integrated Risk Information System (IRIS). Completing this review, a final report of the comments from the workshop were collected and is now available.

30 September 2011

A new Summary for Trichloroacetic acid and a new accompanying Toxicological Review (PDF) (270 pp, 1.92M) have been added to the IRIS Web site. The Interagency Science Discussion Draft of the Trichloroacetic acid IRIS assessment has also been released.

30 September 2011

Notice: IRIS Toxicological Review of Vanadium Pentoxide (External Review Draft Availability & Listening Session Announcement)
EPA announces the release of the draft IRIS Toxicological Review of Vanadium Pentoxide for a 60-day public review and comment period. The Interagency Science Consultation Draft of the Vanadium Pentoxide IRIS assessment has also been released. The deadline for comments is November 29, 2011. [Federal Register Sept 30, 2011]

30 September 2011

Notice: IRIS Toxicological Review of Biphenyl (External Review Draft Availability & Listening Session Announcement)
EPA announces the release of the draft IRIS Toxicological Review of Biphenyl for a 60-day public review and comment period. In addition, EPA has also announced that a public listening session will be held on November 16, 2011 in Arlington, VA. The Interagency Science Consultation Draft of the Biphenyl IRIS assessment has also been released. The deadline for comments is November 29, 2011. [Federal Register Sept 30, 2011]

28 September 2011

An updated Summary for Trichloroethylene and a new accompanying Toxicological Review have been added to the IRIS Web site. The Interagency Science Discussion Draft of the Trichloroethylene IRIS assessment has also been released.

23 September 2011

A new Summary for Hexachloroethane and a new accompanying Toxicological Review (PDF) (200 pp, 1.7M) have been added to the IRIS Web site. The Interagency Science Discussion Draft of the Hexachloroethane IRIS assessment has also been released.

15 September 2011

Notice: IRIS Toxicological Review of n-Butanol (External Review Draft) Extension of Public Comment Period & Listening Session Announcement
EPA has announced an extension of the public comment period for the review of the IRIS Toxicological Review of n-Butanol (External Review Draft) (originally announced in an August 31, 2011 Federal Register Notice) to November 7, 2011. In addition, EPA has rescheduled the listening session to October 26, 2011. [Federal Register Notice Sep 15, 2011]

09 September 2011

Notice: IRIS Toxicological Review of 1,4-Dioxane (Inhalation) (External Review Draft Availability & Listening Session Announcement)
EPA has released the Toxicological Review of 1,4-Dioxane (Inhalation) (External Review Draft) for public review and comment. EPA is extending the close of the public comment period, announced in the August 31, 2011, Federal Register Notice to November 15, 2011. This changes will be announced in a Federal Register Notice shortly. The Interagency Science Consultation Draft of the 1,4-Dioxane (Inhalation) IRIS assessment is temporarily unavailable.

08 September 2011

Notice: IRIS Toxicological Review of n-Butanol (External Review Draft Availability & Listening Session Announcement)
EPA has released the Toxicological Review of n-Butanol (External Review Draft) for public review and comment. EPA is extending the close of the public comment period, announced in the August 31, 2011, Federal Register Notice to November 7, 2011. The listening session, also announced in the August 31, 2011, Federal Register Notice, has been rescheduled to October 26, 2011. These changes will be announced in a Federal Register Notice shortly. The Interagency Science Consultation Draft of the n-butanol IRIS assessment has also been released.

31 August 2011

Notice: Extension of Public Comment Period for IRIS Toxicological Review of Acrylonitrile (External Review Draft)
EPA announces the extension of the public comment period to September 28, 2011 for the draft IRIS Toxicological Review of Acrylonitrile (External Review Draft). [Federal Register Notice Aug 31, 2011]

31 August 2011

Notice: IRIS Toxicological Review of 1,4-Dioxane (External Review Draft Availability & Listening Session Announcement)
EPA announced the draft IRIS Toxicological Review of 1,4-Dioxane in an August 31, 2011 Federal Register Notice, but the document and charge were temporarily unavailable. In addition, EPA also announced that a public listening session will be held on October 18, 2011 in Arlington, VA. [Federal Register Notice Aug 31, 2011]

31 August 2011

Notice: IRIS Toxicological Review of n-Butanol (External Review Draft Availability & Listening Session Announcement)
EPA announced the draft IRIS Toxicological Review of n-Butanol in an August 31, 2011 Federal Register Notice, but the document and charge were temporarily unavailable. In addition, EPA also announced that a public listening session will be held in Arlington, VA. [Federal Register Notice Aug 31, 2011]

29 August 2011

Press Release: EPA Announces Schedule for the Dioxin Assessment & availability of the SAB Final Report
EPA announced the release of the SAB final report of EPA's draft, "Reanalysis of Key Issues Related to Dioxin Toxicity & Response to NAS Comments" which states that the criteria for study selection were applied in a scientifically sound manner and were well described. Additionally, EPA announced its decision to split the dioxin assessment into 2 portions: 1) Non-cancer assessment, which EPA will complete by the end of Jan 2012. When finalized, the non-cancer assessment will mark a significant milestone for EPA because it is the first time the Agency has set an oral reference dose for dioxin; and a 2) Cancer assessment, which EPA will address as expeditiously as possible after the non-cancer assessment is posted to the IRIS database. [Press Release Aug 29, 2011]

25 August 2011

Notice: IRIS Toxicological Review of Libby Amphibole Asbestos (External Review Draft Availability & Listening Session Announcement)
EPA announces the release of the draft IRIS Toxicological Review of Libby Amphibole Asbestos for a 60-day public review and comment period. In addition, EPA has also announced that a public listening session will be held on October 6, 2011. The Interagency Science Consultation Draft of the Libby Amphibole Asbestos IRIS assessment has also been released. [Federal Register Notice Aug 25, 2011]

21 July 2011

Notice: External Peer Review Comments available on the Toxicological Review of Hexavalent Chromium
On May 12, 2011, an external peer review panel meeting was hosted by an independent contractor on the draft Toxicological Review of Hexavalent Chromium: In Support of the Summary Information in the Integrated Risk Information System (IRIS). Completing this review, a final report of the comments from the workshop were collected and is now available.

13 July 2011

A new Summary for Urea and a new accompanying Toxicological Review (PDF) (97 pp, 596K) have been added to the IRIS Web site. The Interagency Science Discussion Draft of the Urea IRIS assessment has also been released.

12 July 2011

EPA Strengthens IRIS Assessment Process
EPA announces a plan to further strengthen and streamline its IRIS assessment development process based on recommendations made by the National Academy of Sciences in an April 2011 evaluation. [Press Release Jul 12, 2011]

30 June 2011

Notice: IRIS Toxicological Review of Acrylonitrile (External Review Draft Availability & Listening Session Announcement)
EPA announces the release of the draft IRIS Toxicological Review of Acrylonitrile for a 60-day public review and comment period. In addition, EPA has also announced that a public listening session will be held on August 10, 2011 in Arlington, VA. The Interagency Science Consultation Draft of the Acrylonitrile IRIS assessment has also been released. [Federal Register Notice Jun 30, 2011]

22 June 2011

Notice: Workshop on the Review of Methanol (non-cancer) in support of IRIS announced along with an addendum to the draft toxicological review document
EPA is announcing an addendum to the IRIS Toxicological Review of Methanol (Non-Cancer) (External Review Draft) document. Included with this announcement is a 14-day public comment period for review of the addendum, and the details for an upcoming public workshop to be held on July 22, 2011 in Durham, NC. The deadline for comments is July 6, 2011. [Federal Register Jun 22, 2011]

18 April 2011

Notice: IRIS Toxicological Review of Methanol (Non-Cancer) (External Review Draft Availability & Listening Session Announcement)
EPA announces the release of the draft IRIS Toxicological Review of Methanol (Non-Cancer) for a 60-day public review and comment period. In addition, EPA has also announced that a public listening session will be held on May 26, 2011 in Arlington, VA. [Federal Register April 18, 2011 ]

12 April 2011

Notice: IRIS Toxicological Review of Hexavalent Chromium Peer Review Workshop
EPA announces that Eastern Research Group, Inc., an EPA contractor for external scientific peer review, will convene an independent panel of experts and organize and conduct an external peer review workshop to review the draft human health assessment titled, "Toxicological Review of Hexavalent Chromium: In Support of Summary Information on the Integrated Risk Information System (IRIS)" on May 12, 2011. [Federal Register April 12, 2011]

11 April 2011

Notice: EPA Announces Plan of Action to Address Four IRIS Assessments
EPA announced its plan to address the four draft Integrated Risk Information System (IRIS) assessments that were placed on hold in June 2010, pending a review of some of the underlying studies relied on in the assessments, per a report written by the National Toxicology Program (NTP), a program administered by the National Institute of Environmental Health Sciences (NIEHS). The four assessments are methanol, methyl tertiary-butyl ether (MTBE), ethyl tertiary-butyl ether (ETBE), and acrylonitrile. EPA and NIEHS decided to jointly sponsor an independent Pathology Working Group (PWG) review, in cooperation with the Ramazzini Institute, of selected studies. The review has begun and will continue over the next several months. [Press Release April 11, 2011]

24 March 2011

The Reference Dose for Chloropyrifos was removed from the IRIS database.

11 March 2011

Notice: Availability of Literature Searches for Four IRIS Assessments
EPA is announcing the availability of literature searches for four IRIS assessments and is requesting scientific information on health effects that may result from exposure to these chemical substances. [Federal Register March 11, 2011 ]

20 January 2011

Publication: External Peer Review Comments available on the Toxicological Review of Urea
On December 13, 2010, an external peer review panel workshop was hosted by an independent contractor on the Toxicological Review of Urea: In Support of the Summary Information in the Integrated Risk Information System (IRIS). Completing this review, a final report of the comments from the workshop were collected and is now available.

13 December 2010

Notice: Availability of Literature Searches for Four IRIS Assessments
EPA is announcing the availability of literature searches for four IRIS assessments and is requesting scientific information on health effects that may result from exposure to these chemical substances. [Federal Register December 10, 2010]

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