Integrated Risk Information System (IRIS)
|IRIS Most Viewed Chemicals||Full List of IRIS Chemicals|
|Acrylamide Arsenic, inorganic Benzene Bisphenol A||Cadmium Chromium (VI) 1,4-Dioxane Formaldehyde||Mercury, elemental Methylmercury (MeHg) Polychlorinated biphenyls (PCBs) Silver|
EPA's Integrated Risk Information System (IRIS) is a human health assessment program that evaluates information on health effects that may result from exposure to environmental contaminants. Through the IRIS Program, EPA provides the highest quality science-based human health assessments to support the Agency's regulatory activities. The IRIS database is web accessible and contains information on more than 550 chemical substances. Learn more.
What's New in IRIS
- 02/06/15: EPA is posting the agenda for the February 2015 IRIS Bimonthly Public Meeting on BBP, DINP, and DBP. The deadlines for registration and comments are posted on the February 25-26, 2015 IRIS Bimonthly Public Meeting.
- 01/16/15: EPA's SAB-CAAC-Benzo[a]pyrene Panel announce two upcoming meetings: a public teleconference on March 4, 2015 to learn about the development of the Agency's draft IRIS assessment and to discuss draft charge questions for the peer review of the document; and then a face-to-face meeting on April 15-17, 2015 to conduct a peer review of the draft document, IRIS Toxicological Review of Benzo[a]pyrene (External Review Draft-September 2014).
- 01/14/15: EPA is releasing the preliminary materials for Dibutyl Phthalate (DBP) to be discussed at the February 2015 IRIS Bimonthly Public Meeting. The deadlines for DBP discussant registration and comments are posted on the February 25-26, 2015 IRIS Bimonthly Public Meeting.
- 12/23/14: EPA announces the availability of the report, SUMMARY REPORT: State-of-the-Science Workshop on Chemically-Induced Mouse Lung Tumors: Applications to Human Health Assessments
- 12/15/14: EPA announces the schedule for the IRIS Bimonthly Public Science Meetings for 2015 in the Federal Register.
- 12/11/14: EPA announces the availability of the presentations from the NRC Recommendations for IRIS Workshop and the presentations from the October 2014 bimonthly science meeting.
- 12/08/14: EPA announces the availability of the Libby Amphibole Asbestos IRIS Assessment in a December 8, 2014 Press Release. In addition, a fact sheet and frequently asked questions are also available.
- 11/21/14: EPA has canceled the December Bimonthly Public Science Meeting on BBP and DIBP and will discuss these chemicals at the February 25-26, 2015 IRIS Bimonthly Public Meeting. EPA opens registration for the February Meeting.
- 11/17/14: SAB announced in the Federal Register a public teleconference of the Science Advisory Board Chemical Assessment Advisory Committee Augmented for the Review of EPA’s Draft Ammonia Assessment.
- 10/15/14: EPA announced that the IRIS Bimonthly Public Science Meetings will be supplemented by scientific experts identified by the National Research Council (NRC). .
Preliminary Draft Materials (by Chemical)
- Arsenic (inorganic)
- Butyl Benzyl Phthalate (BBP), Diisobutyl Phthalate (DIBP) & Dibutyl Phthalate (DBP)
- Chromium (VI) Part 1 & Part 2
- Diethyl Phthalate (DEP) & Hexabromocyclododecane (HBCD)
- Diisononyl Phthalate (DINP)
- ETBE, Tert-Butanol, RDX, EtO and BaP
Draft Assessments under Review
- Ammonia - Revised Aug 2013
- Benzo[a]pyrene - Released Sep 2014
- Ethylene Oxide (inhalation cancer) - Revised Aug 2014
- Trimethylbenzenes - Revised Aug 2013
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Have General Comments for the IRIS Program?
In response to public feedback, EPA has opened a "General Comments Docket" to receive feedback that has broad applicability to the IRIS Program. Comment in the General Docket
NOTE: This docket does not replace the IRIS Hotline, but rather provides another avenue to submit feedback to the IRIS Program.