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Selenourea (CASRN 630-10-4)

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0098

Selenourea; CASRN 630-10-4

Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data, as outlined in the IRIS assessment development process. Sections I (Health Hazard Assessments for Noncarcinogenic Effects) and II (Carcinogenicity Assessment for Lifetime Exposure) present the conclusions that were reached during the assessment development process. Supporting information and explanations of the methods used to derive the values given in IRIS are provided in the guidance documents located on the IRIS website.

STATUS OF DATA FOR Selenourea

File First On-Line 01/31/1987

Category (section)
Status
Last Revised
Oral RfD Assessment (I.A.) withdrawn 02/01/1996*
Inhalation RfC Assessment (I.B.) no data  
Carcinogenicity Assessment (II.) no data  

*A comprehensive review of toxicological studies was completed (2004) - please see section I.A. for more information.

_I.  Chronic Health Hazard Assessments for Noncarcinogenic Effects

_I.A. Reference Dose for Chronic Oral Exposure (RfD)

Substance Name — Selenourea
CASRN — 630-10-4

The Oral RfD for selenourea has been withdrawn on 05/01/1991 pending further review by the RfD/RfC Work Group.

Agency Work Group Review — 08/19/1985, 03/22/1989, 03/27/1991, 07/18/1991, 11/06/1991

A comprehensive review of toxicological studies published prior to 2004 indicated that there is insufficient health effects data to derive an RfD for Selenourea at this time.

EPA Contacts:

Please contact the IRIS Hotline for all questions concerning this assessment or IRIS, in general, at (202)566-1676 (phone), (202)566-1749 (FAX) or hotline.iris@epa.gov (internet address).


_I.B. Reference Concentration for Chronic Inhalation Exposure (RfC)

Substance Name — Selenourea
CASRN — 630-10-4

Not available at this time.

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_II.  Carcinogenicity Assessment for Lifetime Exposure

Substance Name — Selenourea
CASRN — 630-10-4

This substance/agent has not undergone a complete evaluation and determination under US EPA's IRIS program for evidence of human carcinogenic potential.

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_III.  [reserved]
_IV.  [reserved]
_V.  [reserved]


_VI.  Bibliography

Substance Name — Selenourea
CASRN — 630-10-4

Not available at this time.

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_VII.  Revision History

Substance Name — Selenourea
CASRN — 630-10-4

Date
Section
Description
03/31/1987 I.A.6. Documentation corrected
05/01/1989 I.A. Oral RfD summary noted as pending change
12/01/1989 VI. Bibliography on-line
05/01/1991 I.A. Oral RfD withdrawn pending additional review
05/01/1991 VI. Bibliography withdrawn
01/01/1992 IV. Regulatory actions updated
06/01/1992 I.A. Work group review dates added
08/01/1995 I.A., VI. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
02/01/1996 I.A. Contact changed
04/01/1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
12/03/2002 I.A. Screening-Level Literature Review Findings message has been added.
09/29/2004 I.A. Screening-Level Literature Review Findings message has been removed and replaced by comprehensive literature review conclusions.

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_VIII.  Synonyms

Selenourea
CASRN — 630-10-4
Last Revised — 01/31/1987

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