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Acceptable Substitutes in Industrial Process Refrigeration
Substitutes are reviewed on the basis of ozone depletion potential, global warming potential, toxicity, flammability, and exposure potential. Lists of acceptable and unacceptable substitutes are updated several times each year. A chronological list of SNAP updates is also available.
Unacceptable substitutesNote: SNAP-related information published in the Federal Register takes precedence over all information on this page.
Acceptable Substitutes for CFCs (class I ODS) in Industrial Process Refrigeration
| Substitute (Name Used in the Federal Register) | Trade Name | Refrigerant Being Replaced | Retrofit/ New |
|---|---|---|---|
| HCFC-22 | 12, 502 | R, N | |
| HCFC-123 | 11 | R, N | |
| HFC-23 | 13, 13B1, 503 | R, N | |
| Ikon A | 12 | R, N | |
| Ikon B | 12 | R, N | |
| THR-02 | 12 | R, N | |
| HFC-134a | 12 | R, N | |
| HFC-227ea | 12 | N | |
| HFC-236fa | 114 | R, N | |
| R-401A, R-401B | MP-39, MP-66 | 12 | R, N |
| R-402A, R-402B | HP-80, HP-81 | 502 | R, N |
| R-403B | Isceon 69-L | 13, 13B1,
503
Note: R-403B is unacceptable as a substitute for
R-502.
|
R, N |
| R-404A | HP-62 | 502, 12, 500 | R, N |
| R-406A | GHG | 12, 500 | R |
| R-407A, R-407B | Klea 407A, 407B | 502 | R, N |
| R-408A (HCFC Blend Epsilon) | 502 | R | |
| R-411A, R-411B | 12, 500, 502 | R, N | |
| R-507 | AZ-50 | 11, 12, 502 | R, N |
| R-508A (PFC Blend Alpha) | Klea 5R3 | 13, 13B1, 503 | R, N |
| R-508B | Suva 95 | 13, 13B1, 503 | R, N |
| Free Zone (HCFC Blend Delta) | Free Zone / RB-276 | 12 | R, N |
| Freeze 12 | Freeze 12 | 12 | R, N |
| FRIGC FR-12 (HCFC Blend Beta) | FRIGC FR-12 | 12, 500 | R, N |
| GHG-X4 | GHG-X4, Autofrost, Chill-it | 12, 500 | R, N |
| GHG-X5 | GHG-X5 | 12, 500 | R, N |
| GHG-HP (HCFC Blend Lambda) | GHG-HP | 12 | R, N |
| G2018C | G2018C | 12, 500, 502 | R, N |
| Hot Shot | Hot Shot, Kar Kool | 12, 500 | R, N |
| HCFC-22/HCFC-142b | 12 | R, N | |
| NARM-502 | 13, 13B1, 503 | R, N | |
| Carbon Dioxide | 13, 13B1, 503 | R, N | |
| THR-04 | THR-04 | 502 | R, N |
| FOR12A | FOR12A | 12 | R, N |
| FOR12B | FOR12B | 12 | R, N |
| HFC-134a/HBr (92/8) | 12, 502 | N | |
| Ammonia Vapor Compression | 12, 502 | N | |
| HFE-7100 as a secondary heat transfer fluid in not-in-kind systems | 11, 12, 114, 115, 502 | N | |
| HFE-7200 as a secondary heat transfer fluid in not-in-kind systems | 11, 12, 114, 115, 502 | N | |
| Propane,
Propylene, Butane, Hydrocarbon Blend A, Hydrocarbon
Blend B)
Note: These refrigerants are
unacceptable in all
other end-uses.
|
HC-12a®, OZ-12®, Duracool 12a | CFC-12 | R, N |
| Chlorine | all | R, N | |
| Evaporative/Desiccant Cooling | all | N | |
| Hydrofluoroether-7000 (C3F7OCH3) | HFE-7000 | 11, 113 | R, N |
| RS-24 (2002 formulation) | 12 | R, N | |
| CO 2 | 13, 13B1, 503 | R, N | |
| Isceon 39TC | Isceon 39TC | 12 | R, N |
| R-407C | Suva 407C, Klea 407C | 502 | R, N |
| R-420A | Choice R-420A | 12, 500 | R, N |
| R-421B | Choice R421B | 12, 502 | R, N |
| R-426A | RS-24 | 12 | R, N |
| R-422C | ICOR XLT1 | 502 | R, N |
| HFC-245fa | Genetron® 245fa | 114 | R, N |
| KDD6 | KDD6 | 12 | R, N |
Key: R = Retrofit Uses, N = New
Uses
Acceptable Substitutes for HCFCs (class II ODS) in Industrial Process Refrigeration
| Substitute (Name Used in the Federal Register) | Trade Name | Retrofit/ New |
|---|---|---|
| R-410A, R-410B | AZ-20, Suva 9100, Puron | N |
| THR-03 | R, N | |
| Isceon 59, NU-22, R-417A | ISCEON 59, NU-22 | R, N |
| R-404A | HP-62 | R, N |
| R-407C | Suva 9000, Klea 66 | R, N |
| R-507 | AZ-50 | R, N |
| R-125/134a/600a (28.1/70.0/1.9) | R, N | |
| Ammonia Vapor Compression | N | |
| HFE-7100 as a secondary heat transfer fluid in not-in-kind systems | N | |
| HFE-7200 as a secondary heat transfer fluid in not-in-kind systems | N | |
| Ammonia Absorption | N | |
| RS-44 | RS-44 | R, N |
| ISCEON 79 | ISCEON 79 | R, N |
| R-421A | Choice R421A | R, N |
| R-421B | Choice R421B | R, N |
| R-422D | ISCEON MO29 | R, N |
| R-424A | RS-44 | R, N |
| R-426A | RS-44 | R, N | KDD5, R-438A | ISCEON MO99 | R, N | R-434A | RS-45 | R, N | R-428A | RS-52 | N | R-125/290/134a/600a (55.0/1.0/42.5/1.5) | ICOR AT-22 | R, N | R-422B | XAC1, NU-22B | R, N | R-422C | XLT1 | R, N |