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John F. Kenneke
Biographical Information
Name: John F. Kenneke
Title: Research Chemist
Contact Information:
Phone: (706) 355-8247
E-mail: kenneke.john@epa.gov
Education:
Ph.D. in Environmental Chemistry, 1996, University of North Carolina, Chapel Hill
M.S. in Organic Chemistry, 1989, University of Illinois, Urbana-Champaign
B.S. in Chemistry and Biology, 1987, Iowa State University
Expertise/Research Interests:
Xenobiotic metabolism, NMR-based metabonomics, reductive and oxidative degradation of halogenated, organic compounds in natural and engineered systems.
Xenobiotic Metabolism
- In vitro and in vivo metabolism of xenobiotics
- NMR-based metabonomics
- Development of a metabolic simulator for prioritizing chemicals for testing
Natural Attenuation of Halocarbons
- Degradation of halogenated pollutants in natural (e.g., iron and sulfate reducing sediments) and model (e.g., iron sulfide, goethite, and pyrite) systems.
- Identification of reductants in natural systems and their roles in halocarbon degradation as a function of redox zonation.
- Development of quantitative structure activity relationships (QSARs) from natural and model systems to delineate mechanisms of pollutant degradation.
- Incorporation of QSARs into multimedia models.
Engineered Remediation Technologies
- Laboratory and field-scale studies with zero-valent iron for the remediation of chlorinated solvents in ground water. Procedures to enhance zero-valent iron permeable reactive barrier (PRB) performance by retarding or reversing precipitate formation and losses in PRB porosity.
- Fenton chemistry for the remediation of polychlorinated dioxins (PCDD), furans (PCDF), and phenols in contaminated soil.
- Extensive kinetic and mechanistic studies with titanium dioxide photocatalysis and advanced oxidation (AOPs) and reduction processes for the removal of chloroalkenes from water. Chemical and photoelectrochemical techniques to elucidate the mechanisms of chloroalkene degradation and byproduct formation in these systems.
Analytical
- Structure elucidation of unknowns in pharmaceutical and environmental samples analyzed by GC/MS and LC/MS/MS.
- Analytical methods and derivatization techniques for measuring trace levels of halogenated organic compounds in water.
- Physical, electrochemical, GPC, HPLC, and thermal (DTA, DSC, and TGA) analyses of catalysts, semiconductors, polymers, and petroleum samples.
- Stopped-flow techniques to study copper complexation with fulvic acids.
Professional Activities:
Membership
American Chemical Society
Division of Environmental Chemistry, American Chemical Society
Sigma Xi
Remediation Technologies Development Forum (RTDF)
RTDF Permeable Reactive Barriers Action Team
Honors and Awards
Bronze Medal for Commendable Service, U.S. EPA
Superior Accomplishment Recognition Award, U.S. EPA, Athens, GA
National Research Council Research Associateship Award
Hoechst-Celanese Excellence Award in Environmental Sciences and Engineering
Lewis Publishers/American Chemical Society Environmental Chemistry Graduate
Student Award
Smith Graduate Research Award
University of North Carolina Graduate School Travel Award
Select Publications:
Garrison, W.; Ekman, D.; Kenneke, J.; Mazur, C. 2004. Enantiomer-specific effects of chiral pollutants. 4th SETAC World Congress, November 14-18, Portland, OR
Jones, W. J.; O’Niell, W. L.; Mazur, C. S.; Kenneke, J. F.; Garrison, A. W. 2003. Enantioselective transformation of chiral PCBs and the insecticide Fipronil in natural anoxic sediments. 23rd International Symposium on Halogenated Organic Pollutants and Persistent Organic Pollutants, August 24-29, Boston, MA
Collette, T. W.; Hilal, S. H.; Jones, W. J.; Kenneke, J. F.; Mazur, C.S.; Suárez, L. A.; Tebes-Stevens, C. L.; Washington, J. W.; Weber, E. J.; Wolfe, K. L.; Wolfe, N. L. 2003. Modeling Chemical Fate and Metabolism for Computational Toxicology. EPA Science Forum, Washington, D.C.
Garrison, A. W.; Jones, W. J.; Avants, J.; Mazur, C. S.; Kenneke, J. F. 2003. The Enantiomers of Chiral Pollutants Pose Different Risks. EPA Science Forum, Washington, D.C.
Kenneke, J. F.; McCutcheon, S. C. 2003. The use of pre-treatment zones with zero-valent iron for the remediation of chloroalkenes in an oxic aquifer. Environmental Science and Technology, 37: 2829-2835.
Kenneke, J. F.; Weber, E. J. 2003. Reductive dehalogenation of halomethanes in iron- and sulfate-reducing sediments. 1. Reactivity pattern analysis. Environmental Science and Technology 37: 713-720.
Weber, E. J.; Kenneke, J. F.; Hoferkamp, L. A. 2002. Reactivity of chemical reductants as a function of redox zonation. Groundwater Quality: Natural and Enhanced Restoration of Groundwater Pollution. Thorton, S. F. and Oswald, S. E. eds., IAHS Press, UK , 113-118.
Kenneke, J. F.; Weber, E. J. 2000. Reductive dehalogenation of halomethanes in natural and model systems: QSAR analysis. American Chemical Society, 220th National Convention, Division of Environmental Chemistry, August 20-25, Washington, D. C.
Shira, B. A.; Anderson; J. L., Kenneke, J. F.; Weber, E. J. 2000. Haloacetic acid formation from the abiotic reduction of chloroalkanes and chloroalkenes. Pittcon, March 12-17, New Orleans, LA.
Kenneke, J. F.; Mc Cutcheon, S. C. 1999. A long-term laboratory and field study on the degradation of PCE with zero-valent iron. The Geological Society of America Southeastern Conference, March 25-26, Athens, GA.
Kenneke, J. F.; Mc Cutcheon, S. C. 1998. The effects of chemical additives on pollutant removal and zero-valent iron reactivity. Battelle, First International Conference on the Remediation of Chlorinated and Recalcitrant Compounds, May18-21, Monterey, CA.
Yabusaki, S.; Steefel, C.; Kenneke, J.; Dortch, M. 1998. In situ treatment in a funnel and gate treatment system. Second DoD Environmental Security Modeling and Simulation Conference, May 4-6, Alexandria, VA.
Yabusaki, S.; Steefel, C.; Cantrell, K.; Kenneke, J. 1998. Reactive transport in a funnel and gate treatment system. American Geophysical Union, May, Boston, MA.
Glaze, W. H.; Le Lacheur, R. M.; Pullin, J. J.; Maddox, D. S.; Ferry, J. L.; Kenneke, J. F.; Loraine, G. A.; Tracy, T. L. 1995. By-products of oxidation processes in water and wastewater treatment. American Chemical Society, 210th National Convention, Division of Environmental Chemistry, August 21-26, Chicago, IL.
Kenneke, J. F.; Glaze, W. H. 1994. The photoelectrochemical degradation of chloroalkenes on particulate titanium dioxide electrodes. The Electrochemical Society, 185th Meeting, May 22-27, San Francisco, CA.
Kenneke, J. F.; Ferry, J. L.; Glaze, W. H. 1994. The origin of chlorinated byproducts from the titanium dioxide-mediated photodegradation of chloroalkenes in water. American Chemical Society, 207th National Convention, Division of Environmental Chemistry, March 13-18, San Diego, CA.
Kenneke, J. F.; Ferry, J. L.; Glaze, W. H. 1993. The titanium dioxide mediated photocatalytic degradation of chloroalkenes in water. Photocatalytic Purification and Treatment of Water and Air. Ollis, D. F. and Al-Ekabi, H. eds. Elsevier: New York, 179-191.
Glaze, W. H.; Kenneke, J. F.; Ferry, J. L. 1993. Chlorinated byproducts from the titanium dioxide-mediated photodegradation of trichloroethylene and tetrachloroethylene in water. Environmental Science and Technology 27:177-184.
Glaze, W. H.; Kenneke, J. F.; Ferry, J. L. 1992. Mechanisms and by-products of the titanium dioxide mediated photo-oxidation of trichloroethylene and tetrachloroethylene in aqueous solutions. First International Conference on titanium dioxide Photocatalytic Purification and Treatment of Water and Air, November 8-13, London, Ontario, Canada, 39-40.
Kenneke, J. F.; Ferry, J. L.; Glaze, W. H. 1992. Chlorinated by-products from titanium dioxide-mediated photocatalysis and hydrogen peroxide-photooxidation of chloroalkenes in water. American Chemical Society, 203rd National Convention, Division of Environmental Chemistry, April 5-10, San Francisco, 32:1, 100-3.
Current Projects:
Phase I and Phase II metabolism of conazole fungicides in rat liver microsomes
- Environmental applications of NMR-based metabonomics .
- Development of a structure searchable data base and metabolic simulator for prioritizing chemicals for testing.
- Iron oxide and iron sulfide mediated reductive transformations of halocarbons.
- Identification of chemical reductants in sediment systems using model systems and measuring reactivity patterns of halogenated probe chemicals.
- Redox characterization of sediments and aquifer materials.