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EDRI Federal Project Inventory:
61093-03 Epidemiology of Epithelial Ovarian Cancer
- Sponsor Organization: NIH/NCI
- Project Title: 61093-03 EPIDEMIOLOGY OF EPITHELIAL OVARIAN CANCER
- Project Focus: HUMAN HEALTH EFFECTS
- Description: A population-based case-control study of epithelial ovarian cancer,
which will investigate the association betweengenital talc use,
infertility, infertility treatments, hormone use, oral contraceptive
use, gynecologic operations, nutritionalfactors and physical activity
and the development of epithelial ovarian cancer is proposed. The
study will be performedin the multi-ethnic, multi-racial community of
Cook County, Illinois. Approximately 750 incident epithelial
ovariancancer cases occurring in this community will be ascertained
over a three year period. Histologic specimens obtainedduring
diagnostic operation of the case will be evaluated by the study
pathologist to consistently classify histologicsubtype and degree of
malignancy. Approximately 1500 population controls, matched on age
and race, will beascertained using random digit dialing (less than
age 65) and lists of medicare recipients maintained by the Health
CareFinancing Administration (age 65 or higher). Etiologic
information will be ascertained using a self administered food-
frequency questionnaire and an in-person interview. Analyses will be
performed using conditional logistic regressionand polychotomous
logistic regression.
- References:
- Category: MEASUREMENTS
- Subcategory: EXPOSURE DETERMINATIONS/FOLLOW UP
- Keywords for Experimental System/Species: HUMAN, FIELD STUDY
- Keywords for Experimental Endpoints: CARCINOGENESIS, FEMALE, EPIDEMIOLOGY
- Chemical Agents: ORAL CONTRACEPTIVES
- Performing Institution: UNIVERSITY OF ILLINOIS AT CHICAGO
- Contact: ELAINE C. LEE; BUILDING 31; 11A21, NATIONAL CANCER INSTITUTE,
NIH,BETHESDA, MD 20892-2590; 301- 496-5515; LEEE@OD.NCI.NIH.GOV
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