EDRI Federal Project Inventory:
66223-02 Environmental Factors Influencing Breast Cancer
- Sponsor Organization: NIH/NCI
- Project Title: 66223-02 ENVIRONMENTAL FACTORS INFLUENCING BREAST CANCER
- Project Focus: HUMAN HEALTH EFFECTS, EXPOSURE ASSESSMENT
- Description: The University of Michigan Comprehensive Cancer Center proposes to
expand its Breast Cancer Research Programto focus on environmental
factors influencing breast cancer. The proposed program represents a
collaborative effortbetween the Cancer Center and the School of Public
Health and the Department of Environmental Sciences. Thisprogram will
draw upon the extensive research base at the University of Michigan
Cancer Center in molecular biology,carcinogenesis and genetics, and
combine this with the strengths of the School of Public Health in
environmentalsciences, nutrition sciences and cancer epidemiology. In
order to stimulate research in this area, the program will holdmonthly
research meetings between investigators in the School of Public Health
and those in the Breast Cancer Program. In addition, yearly retreats
will be held in which outside researchers involved in relevant areas
of research will bebrought to the University. The program will also
fund pilot projects dealing with research related to
environmentalfactors and breast cancer. A committee with expertise in
environmental health sciences and cancer research will reviewthese
proposals which will be awarded for a l to 3 year period. Development
funds will also be utilized to providepartial funding to recruit an
investigator with a focus on environmental sciences and cancer. This
program will initiallyfocus on two areas. The first will involve
issues regarding nutrition and breast cancer etiology. The second
area offocus will be the role of environmental carcinogens in breast
cancer etiology. The program will fund a pilot project ineach area.
Each of these areas will involve research collaborations between
investigators in environmental healthsciences and nutrition, and basic
scientists in cellular and molecular biology. In addition,
investigators interested incancer genetics will be involved in this
program. The ultimate aim of this program is to better understand
themechanisms by which environmental factors interact with genetic
factors in breast cancer development. At theconclusion of this grant
period the Cancer Center will have developed a broad based program to
investigate the effect ofenvironmental factors on breast cancer
development.
- References:
- Category: METHODS
- Subcategory: MULTIDISCIPLINARY RESEARCH
- Keywords for Experimental System/Species: HUMAN, FIELD STUDY
- Keywords for Experimental Endpoints: CARCINOGENESIS, MOLECULAR, RISK FACTORS
- Chemical Agents: ENVIRONMENAL CARCINOGENS
- Performing Institution: UNIVERSITY OF MICHIGAN AT ANN ARBOR
- Contact: CONTACT PERSON: ELAINE C. LEE; BUILDING 31; 11A21, NATIONAL CANCER
INSTITUTE, NIH, BETHESDA, MD 20892-2590; 301- 496-5515;
LEEE@OD.NCI.NIH.GOV
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