Description: The objective of this contract is to provide continued follow-up of
surviving members of the well characterized DES-exposed cohorts which
will be used to estimate cancer risks in the entire population of
approximately 10 millionexposed individuals. In addition, existing
cohorts will be combined and extended to include previously
unstudiedexposed individuals in the families, so the total resource
will add value to the existing smaller components. Finally,
thefeasibility of identifying a cohort of grandchildren will be
investigated. This work is being supported by theEnvironmental
Epidemiology Branch (EEB), Epidemiology & Biostatistics Program (EBP),
Division of Cancer Etiology(DCE) of the National Cancer Institute
(NCI).
References:
Category: MEASUREMENTS
Subcategory: EXPOSURE DETERMINATIONS/FOLLOW UP
Keywords for Experimental System/Species: HUMAN, FIELD STUDY
Keywords for Experimental Endpoints: CARCINOGENESIS, EXPOSURE MONITORING
Chemical Agents: DES
Performing Institution: UNIVERSITY OF MASSACHUSETTS MEDICAL SCH
Contact: ELAINE C. LEE; BUILDING 31; 11A21, NATIONAL CANCER INSTITUTE,
NIH,BETHESDA, MD 20892-2590; 301- 496-5515; LEEE@OD.NCI.NIH.GOV
