|
 |
|
EDRI Federal Project Inventory:
Chemistry and Biology of Ecdysis-Triggering Hormones
- Sponsor Organization: NATIONAL SCIENCE FOUNDATION
- Project Title: CHEMISTRY AND BIOLOGY OF ECDYSIS-TRIGGERING HORMONES
- Project Focus: ECOLOGICAL EFFECTS
- Description: Insect growth and development is associated with repeated shedding of
the oldexoskeleton or cuticle in a process called ecdysis. The
successful performance of thiscomplex behavior is crucial to the
survival of developing insects. It appears that anewly described
novel endocrine system regulates ecdysis in moths and may beimportant
to this developmental process in all insects. This novel endocrine
systemappears to produce multiple hormones. The identification of
these hormones isparamount to Dr. Adams' research endeavor. Once
these factors have been chemical identified, reagents will be prepared
that allow the localization and quantification of thehormones in the
insect during development. Finally, the site and mechanism
ofecdysis- triggering hormone action will be elucidated. This unique
endocrine systemprovides opportunities to study the hormonal
regulation of development and behaviorfrom the molecular to the
organismal level including information regarding theregulation of
hormone synthesis, release and physiological action.
Furthermore,premature administration of ecdysis- triggering hormone
to early stages of larvae andpupae is lethal, these hormones may prove
to be of great commercial significance inthe biological control of
insect pests.
- References:
- Category: MODELS
- Subcategory: BASIC RESEARCH
- Keywords for Experimental System/Species: INVERTEBRATES, IN VIVO, LABORATORY STUDY
- Keywords for Experimental Endpoints: NEUROLOGICAL, REPRODUCTIVE, HORMONE MEASURES, PEPTIDE HORMONES,
BREEDINGBEHAVIOR, MOLECULAR, PHYSIOLOGY
- Chemical Agents: Peptide Hormones, Reproductive Steroids
- Performing Institution: University of California Riverside
- Contact: Michael E Adams, 900 University Avenue, Riverside, CA 92521-0101
714 787-1012, adams@mail.ucr.edu
|
|
