EDRI Federal Project Inventory:
Neural and Hormonal Substrates of Reproductive Behavior
- Sponsor Organization: NATIONAL SCIENCE FOUNDATION
- Project Title: NEURAL AND HORMONAL SUBSTRATES OF REPRODUCTIVE BEHAVIOR
- Project Focus: HUMAN HEALTH EFFECTS
- Description: Reproductive success in most species depends on both humoral and
neuralresponses acting coordinately. The majority of studies have
focused on the male asthe critical component for determining
successful outcomes, however, femalereproductive tract function is
also significant, and yet under investigated. In the presentwork,
Dr. Clemens will focus on the effects of hormones on uterine
contractions andthe role of these contractions in the initiation of
pregnancy. By recording electricalactivity of uterine muscles, it
will be possible to determine what stimuli are important forthe
induction of uterine activity around the time of ovulation and whether
theseresponses are associated with the release of hormones from the
ovary involved in theinitiation of pregnancy. The experiments will
provide new and exciting information onthe role of the female
reproductive system in pregnancy initiation and reproductivesuccess in
mammals.
- References:
- Category: MODELS
- Subcategory: BASIC RESEARCH
- Keywords for Experimental System/Species: RODENT, MAMMAL, IN VIVO, LABORATORY STUDY
- Keywords for Experimental Endpoints: NEUROLOGICAL, REPRODUCTIVE, HORMONE MEASURES, SEX STEROIDS, PEPTIDE
HORMONES,PHYSIOLOGY, BREEDING BEHAVIOR,
- Chemical Agents: Sex Steroids
- Performing Institution: Michigan State University
- Contact: Lynwood G Clemens, East Lansing, MI 48824 517 355-1855
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