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David C. Bencic

My current research focuses on using molecular methods, specifically changes in gene and protein expression, for the identification of ecological aquatic exposure indicators. I serve as a NERL lead for a computational toxicology project entitled, "Linkage of Exposure and Effects Using Genomics, Proteomics, and Metabolomics in Small Fish Models." I participate in the microarray and quantitative polymerase chain reaction (QPCR) analysis of zebrafish (Danio Rerio) and fathead minnow (Pimephales promelas) samples. In addition, I perform two dimensional polyacrylamide gel electrophoresis (2-D PAGE), specifically the fluorescence-based DIGE technology, for this project. Finally, I also use these molecular-based expression tools to collaborate with other EERD and EPA scientists to identify indicators of exposure to a variety of other chemicals, including emerging contaminants and pesticide/pesticide mixtures, in both laboratory and field experiments.

Biographical Information

Name: David C. Bencic
Title: Research Biologist

Contact Info:

Ecological Exposure Research Division
National Exposure Research Laboratory
Environmental Protection Agency
26 W. Martin Luther King Jr. Dr. (MD579)
Cincinnati, OH 45268

Phone: 513-569-7201


  • Ph.D. in Zoology, 1999, University of Idaho
  • B.A. in Biology, 1993, Kalamazoo College

Professional Experience:

  • Research Biologist, USEPA, ORD/NERL, 2004 to Present
  • Post-Doctoral Fellow, Duke University, Integrated Toxicology Program, 2002 to 2004
  • Post-Doctoral Fellow, University of North Carolina, 2000 to 2002
  • Post-Doctoral Fellow, University of Idaho, 2000

Selected Awards and Honors:

  • USEPA, ORD Honor Award for Teamwork for the Small Fish Computational Toxicology Team, 2010
  • USEPA, STAA Award, Level III, for Investigation of the Adaptive Capabilities of Biological Systems and Their Dynamic Responses to Chemical Stressors, 2010
  • USEPA, STAA Award, Level III, for Applying Mechanistic Toxicology to Ecological Risk Assessment of Endocrine-Active Chemicals, 2010
  • USEPA, STAA Award, Honorable Mention, for Work Which Aided States and US EPA Regional Laboratories in Estrogenic Exposure Assessments of Aquatic Ecosystems, 2008
  • USEPA, ORD Honor Award for Exceptional/Outstanding ORD Technical Assistance to Regions or Program Offices, 2007

Publications and Presentations

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