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Endocrine Disruptor Methods Validation Subcommittee (EDMVS)

Third Plenary Meeting - March 25-27, 2002


PDF File [3pp., 31KB, About PDF] HTML File [16KB]

Federal Register Notices Announcing Meeting | Copy for Public Comment

Endocrine Disruptor Method Validation Subcommittee Under the National Advisory Council for Environmental Policy and Technology; Notice of Public Meeting [PDF file, 3pp., 45KB, About PDF]

Background Documents and Corresponding Presentation(s)

In Utero through Lactation Protocol

Validation of the In Utero/Lactational Exposure Screening Protocol with Methoxychlor [PDF file, 41pp., 480KB, About PDF]

Anticipated Effects of Various Endocrine-Active Chemicals in the IUL Screening Protocol [PDF file, 6pp., 48KB, About PDF]

IUL Study Plan Questions [PDF file, 1pp., 64KB, About PDF]

Fish Assays

A Short-Term Test Method for Assessing the Reproduction Toxicity of Endocrine-Disrupting Chemicals Using the Fathead Minnow by US EPA National Health and Environmental Effects Research Laboratory (NHEERL), Midcontinent Ecology Division - Not available electronically - SEE Docket ID: EPA-HQ OPPTS - 42212F.

Draft Detailed Review Paper on Fish Screening Assay for Endocrine Disruption (Introduction and Questions) [PDF file, 1pp., 62KB, About PDF]

Draft Detailed Review Paper for Endocrine Disruption [PDF file, 123pp., 992KB, About PDF]

Draft Study Plan for the Comparative Evaluation of Fathead Minnow Assays for Detecting Endocrine-Disrupting Chemicals (Introduction and Questions) [PDF file, 1pp., 66KB, About PDF]

Draft Study Plan: Comparative Evaluation of Fathead Minnow Study Plan for Detecting Endocrine-Disrupting Chemicals [PDF file, 31pp., 362KB, About PDF]

Presentation: Comparative Evaluation of Fathead Minnow Assays [PPT file, 5pp., 49KB]

Draft Study Plan for the Comparative Evaluation of Vitellogenin Methods (Introduction and Questions) [PDF file, 1pp., 65KB, About PDF]

Draft Study Plan: Comparative Evaluation of Vitellogenin Methods [PDF file, 9pp., 171KB, About PDF]

Presentation: Comparative Evaluation of Vitellogenin Methods [PPT file, 5pp., 49KB]

Short-term Fish Reproduction Assay - Not available electronically.

Presentation: Short-term Fish Screening Assay Detailed Review Paper [PPT file, 22pp., 213KB]

Avian Assays

Draft Study Plan (Introduction and Questions) [PDF file, 1pp., 72KB, About PDF]

Dosing Study Plan [PDF file, 44pp., 527KB, About PDF]

Presentation: Special Study: Tier 2 Avian Dosing Study [PPT file, 3pp., 212KB]

Aromatase Assay

Revised Detailed Review Paper [PDF file, 85pp., 998KB, About PDF]

Questions Regarding Aromatase [PDF file, 1pp., 59KB, About PDF]

Steroidogenesis Assay

Presentation: Detailed Review Paper [PPT file, 27pp., 394KB]

Other Topics

Presentation: Chemicals Used in Prevalidation of EDSP-Related Assays [PPT file, 22pp., 423KB]

EPA's approach to Addressing Low Dose Issues [PDF file, 1pp., 23KB, About PDF]

Presentation: EDMVS Workplan [PPT file, 24pp., 95KB]

Presentation: Overview of Ecotoxicological Assays [PPT file, 17pp., 420KB]

Presentation: Practical Aspects of the Implementation of the Validation Process by EDSP [PPT file, 19pp., 59KB]

Presentation: Sources of Data Used in Assessing Human Effects [PPT file, 20pp., 98KB]

Public Comments

American Chemistry Council [PDF file, 4pp., 30KB, About PDF]

Crop Life of America [PDF file, 8pp., 456KB, About PDF]

World Wildlife Fund [PDF file, 18pp., 58KB, About PDF]

Meeting Summary

Meeting Summary [PDF file, 35pp., 54KB, About PDF]


Some of the documents presented may not be accessible using alternative access devices. If you need access to these documents please contact William Wooge at 202-564-8476. We will post accessible documents as soon as possible.

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