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National Advisory Council for Environmental Policy and Technology (NACEPT)
Endocrine Disruptor Methods Validation Subcommittee (EDMVS)
Plenary Meeting - August 18 - 20, 2003

Table Mountain Inn
1310 Washington Avenue
Golden, CO 80401
(303) 216-8040

Proposed Agenda

Meeting Objectives:

1. Review and discuss the status/results of the prevalidation work on:

2. Provide input and advice on the:

3. Receive an update on the amphibian workshop conducted recently.

Monday, August 18, 2003

1:30 - 1:40 Welcome and Opening Comments
Joe Merenda, EDMVS Chair and Director, Office of Science Coordination and Policy (OSCP), EPA

1:40 - 2:00 Introduction, Agenda Review, and Review of Previous Meeting Summary
Paul De Morgan, Facilitator, RESOLVE

2:00 - 2:30 Review of EDMVS Work Plan
Jane Smith, EDMVS Designated Federal Official, OSCP, EPA

2:30 - 3:45 Presentation on Fish Screening Assays:
-- Results of the Survey of Vitellogenin Methods in Fathead Minnow
-- Results of the Survey of Vitellogenin Methods in Zebrafish and Medaka
Michael Blanton, Battelle

3:45 - 4:00 Break

4:00 - 4:45 Presentation on Fish Screening Assay: Results of the Comparative Evaluation of the Fathead Minnow
Michael Blanton, Battelle

4:45 - 5:15 Presentation on OECD Phase 1A: Feasibility to Demonstrate the Fish Screen (Nonspawning) Method
Dr. Hirofumi Yokota, Chemicals Evaluation and Research Institute (CERI), Japan

5:15 - 5:45 Public Comment
Members of the public will be given an opportunity to comment on any aspect of the EDMVS work. The amount of time given to each individual will depend on the number of people wishing to provide comment.

5:45 Adjourn

Tuesday, August 19, 2003

7:45 - 8:00 Settling In

8:00 - 9:30 Discussion of the Fish Screening Assay

9:30 - 10:00 Overview of Amphibian Workshop
Dr. Les Touart, OSCP, EPA

10:00 - 10:15 Break

10:15 - 12:30 Presentation and Discussion on Strain/Species
Dr. Sherry Parker, Research Triangle Institute (RTI)

12:30 - 1:30 Lunch

1:30 - 2:30 Update on Chemicals Used for EDSP’s Prevalidation and Validation
Gary Timm, OSCP, EPA

2:30 Adjourn

Wednesday, August 20, 2003

8:00 - 8:15 Settling In

8:15 - 10:15 Presentation and Discussion of Avian Detailed Review Paper
Dr. Les Touart, OSCP, EPA

10:15 - 10:30 Break

10:30 - 12:00 Issues Related to the Pubertal Assay
Jim Kariya, OSCP, EPA

12:00 - 1:00 Lunch

1:00 - 1:30 Presentation on Steroidogenesis Assay Optimized Protocol
Carol Sloan, RTI

1:30 - 2:30 Presentation and Discussion on Steroidogenesis Validation Study Plan
Gary Timm, OSCP, EPA

2:30 - 2:45 Break

2:45 - 3:15 Public Comment
Members of the public will be given an opportunity to comment on any aspect of the EDMVS work. The amount of time given to each individual will depend on the number of people wishing to provide comment

3:15 - 3:30 Next Steps and Agenda for Next Meeting

3:30 Adjourn


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