National Advisory Council for Environmental Policy and Technology (NACEPT)
Endocrine Disruptor Methods Validation Subcommittee (EDMVS)
Meeting by Conference Call - December 4, 2002 (10:00 a.m. - 12:00 noon EST)
Members of the public may join this conference call in person at the conference room in the RESOLVE offices at 1255 23rd St. NW, Suite 275, Washington, DC. To register to participate by phone, please contact Jane Smith, designated federal official for the EDMVS, at firstname.lastname@example.org or (202) 564-8476. Also note that members of the public who would like to make comments during the conference call need to contact Ms. Smith prior to the
- Provide comments and advice on the Fish Lifecycle DRP (Tier II).
10:00 - 10:05 Phoning in
10:05 - 10:10 Welcome and Opening Comments
- Roll Call
- Overview of FACA Requirements
10:10 - 10:30 Fish Lifecycle DRP (Tier II) Presentation
Dr. Les Touart, Office of Science Coordination and Policy (OSCP), EPA
10:30 - 11:40 Discussion on Fish Lifecycle DRP
The purpose of this DRP is to define the basis and purpose of the proposed two generation test for evaluating endocrine effects. The DRP summarizes, explains, and documents decisions regarding the relevant principles, methods, and techniques recommended for an initial protocol with four candidate species of fish (fathead minnow, zebrafish, medaka, and sheepshead minnow), and identifies issues that might require prevalidation studies to adequately address information gaps. Please use the following questions as a guide for your feedback to EDSP:
- Does the EDMVS agree that the two-generation method recommended and
applicable to four species of fish is appropriate?
- Does the EDMVS agree that prevalidation should evaluate the increased
sensitivity of a two-generation design over the existing fish full life-cycle
- Does the EDMVS agree that prevalidation should demonstrate the sensitivity
and reproducibility for each species in the recommended protocol?
- Does the EDMVS have suggestions to improve the DRP?
11:40 - 11:55 Public Comment
Members of the public who would like to make comments during the conference call must contact Jane Smith, designated federal official for the EDMVS, at email@example.com or (202) 564-8476. Members of the public are requested to focus their comments on issues related to the Fish Lifecycle DRP to the extent possible.
11:55 - 12:00 Next Steps