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National Advisory Council for Environmental Policy and Technology (NACEPT)
Endocrine Disruptor Methods Validation Subcommittee (EDMVS)
Plenary Meeting - December 10-12, 2003

DRAFT Agenda

RESOLVE
1255 23rd Street, N.W., Suite 275
Washington, DC 20037
(202) 944-2300

Meeting Objectives

  1. Discuss the pubertal assay and aromatase assay prevalidation results and recommend next steps.
  2. Receive introductory presentation on adult intact male assay.
  3. Receive updates on:

Wednesday, December 10, 2003

1:00 - 1:10 Welcome and Opening Comments

Joe Merenda, EDMVS Chair and Director, Office of Science Coordination and Policy (OSCP), EPA

1:10 - 1:30 Introduction, Agenda Review, and Review of Previous Meeting Summary

Paul De Morgan, Facilitator, RESOLVE

1:30 - 2:00 Review of EDMVS Work Plan

Jane Smith, EDMVS Designated Federal Official, OSCP, EPA

2:00 - 3:00 Update on Androgen Receptor Binding Assay

Presenter TBD

3:00 - 3:15 Break

3:15 - 4:15 Update on Reference Chemicals

Gary Timm, OSCP, EPA

4:15 - 4:45 Public Comment

Members of the public will be given an opportunity to comment on any aspect of the EDMVS work. The amount of time given to each individual will depend on the number of people wishing to provide comment.

4:45 Adjourn

Thursday, December 11, 2003

8:30 - 8:45 Settling In

8:45 - 11:45 (with break) Presentation and Discussion of Reproductive Endpoints of the Pubertal Assay

L. Earl Gray, Ph.D., Reproductive Toxicology Division, National Health and Environmental Effects Research Laboratory (NHEERL), Office of Research and Development (ORD), EPA

11:45 - 1:00 Lunch

1:00 - 1:45 Presentation of the Pubertal Assay Thyroid Endpoints

Susan Laws, Ph.D., Reproductive Toxicology Division, NHEERL, ORD, EPA

1:45 - 3:45 Discussion of Issues Associated with the Pubertal Assays and Interlaboratory Variability

Jim Kariya, OSCP, EPA

3:45 - 4:30 Presentation of Aromatase Assays

Presenter TBD

4:30 - 5:00 Public Comment

Members of the public will be given an opportunity to comment on any aspect of the EDMVS work. The amount of time given to each individual will depend on the number of people wishing to provide comment

5:00 Adjourn

Friday, December 12, 2003

8:30 - 8:45 Settling In

8:45 - 9:45 Discussion of Aromatase Assays

Gary Timm, OSCP, EPA

9:45 - 10:45 Preliminary Presentation on the 14-Day Adult Intact Male Assay

Rick Becker, Ph.D., American Chemistry Council
Gary Timm, OSCP, EPA

10:45 - 11:00 Break

11:00 - 11:45 Update on OECD Ecotoxicity Activities

Les Touart, OSCP, EPA

11:45 - 12:00 Next Steps and Agenda for Next Meeting

12:00 Adjourn


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