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Early Priority Setting Activities

Prior to publishing the proposed approach in December 2002 for the selection of the initial list of chemicals for Tier 1 screening, EPA conducted various activities which contributed to the development of the approach. EPA anticipates that it will modify its chemical selection approach for subsequent Tier 1 Screening lists based on experience gained from the results of testing chemicals on the initial list, the feasibility of incorporating different categories of chemicals (e.g., non-pesticide substances), additional pathways of exposure, and the availability of new priority setting tools (e.g., HTPS or QSAR models).

EDSTAC Priority Setting Workgroup (1996 - 1998)

The need for priority setting originated from recommendations made in 1998 by a Federal advisory committee, the Endocrine Disruptor Screening and Testing Committee (EDSTAC). EDSTAC formed a Priority Setting Workgroup that was charged to address the following tasks:

EPA's Strawman Proposal (1998 - 1999)

EPA developed an initial "Strawman" proposal [PDF file, 27pp., 48KB, About PDF] for further defining and implementing a compartment-based system based on the framework and guiding principles recommended in the EDSTAC report. EPA held a public workshop to discuss the Strawman in January of 1999. A summary of the workshop is available. [PDF file, 26pp., 111KB, About PDF] out of date

EPA's Endocrine Disruptor Priority Setting Database (1999 - 2001)

Beginning in 1999, EPA also developed version 2 of the Endocrine Disruptor Priority Setting Database (EDPSD v.2). EDPSD v.2 was designed to assist EPA in setting priorities for chemical selection. EPA held two public workshops that discussed EDPSD. Summaries of the January 1999 [PDF file, 26pp., 140KB, About PDF] out of date and June 2000 [PDF file, 55pp., 111KB, About PDF] out of date workshops are available.

You will need the free Adobe Reader to view some of the files on this page. See EPA's PDF page to learn more. If you need help accessing these PDF documents, please contact William Wooge at 202-564-8476 or wooge.william@epa.gov for assistance.

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