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FIFRA Scientific Advisory Panel; Notice of Public Meeting
Note: EPA no longer updates this information, but it may be useful as a reference or resource.
[Federal Register: May 31, 2002 (Volume 67, Number 105)]
[Notices]
[Page 38104-38106]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr31my02-89]
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ENVIRONMENTAL PROTECTION AGENCY
[OPP-2002-0083; FRL-7180-7]
FIFRA Scientific Advisory Panel; Notice of Public Meeting
AGENCY: Environmental Protection Agency (EPA).
ACTION: Notice.
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SUMMARY: There will be a 3-day meeting of the Federal Insecticide,
Fungicide, and Rodenticide Act (FIFRA) and Food Quality Protection Act
(FQPA) Scientific Advisory Panel (FIFRA SAP) to consider and review two
topics. The first topic is to update the FIFRA SAP
[[Page 38105]]
on the status of preliminary results from cumulative risk estimates for
organophosphate pesticides (OP) using alternative models (Calendex\TM\,
LifeLine\TM\, and CARES\TM\) and similar input data and parameters. The
second topic is review of cumulative risk assessments for OPs:
Susceptibility and age dependent sensitivity.
DATES: The meeting will be held from June 25-27, 2002, from 8:30 a.m.
to 5 p.m, eastern standard time.
For dates on requests to present oral comments, submission of
written comments, or requests for special seating arrangements, see
Unit I.C. of the SUPPLEMENTARY INFORMATION.
ADDRESSES: The meeting will be held at the Sheraton Crystal City Hotel,
1800 Jefferson Davis Hwy., Arlington, VA. The telephone number for the
Sheraton Crystal City Hotel is (703) 486-1111.
Requests to present oral comments, submission of written comments,
or requests for special seating arrangements may be submitted by mail,
electronically, or in person. Please follow the detailed instructions
for each method as provided in Unit I. of the SUPPLEMENTARY
INFORMATION. To ensure proper receipt by EPA, your request must
identify docket ID number OPP-2002-0083 in the subject line on the
first page of your response.
FOR FURTHER INFORMATION CONTACT: Olga Odiott, Designated Federal
Official (DFO), for topic 1 or Paul Lewis, DFO, for topic 2, Office of
Science Coordination and Policy (7202M), Environmental Protection
Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460; telephone
number: (202) 564-8450; fax number: (202) 564-8382; e-mail addresses:
olga.odiott@epa.gov or lewis.paul@epa.gov.
SUPPLEMENTARY INFORMATION:
I. General Information
A. Does this Action Apply to Me?
This action is directed to the public in general. This action may,
however, be of interest to persons who are or may be required to
conduct testing of chemical substances under the Federal Food, Drug,
and Cosmetic Act (FFDCA), FIFRA, and FQPA. Since other entities may
also be interested, the Agency has not attempted to describe all the
specific entities that may be affected by this action. If you have any
questions regarding the applicability of this action to a particular
entity, consult one of the DFOs listed under FOR FURTHER INFORMATION
CONTACT.
B. How Can I Get Additional Information, Including Copies of this
Document and Other Related Documents?
1. Electronically. You may obtain electronic copies of this
document, and certain other related documents that might be available
electronically, from the EPA Internet Home Page at http://www.epa.gov/.
To access this document, on the Home Page select ``Laws and
Regulations,'' ``Regulations and Proposed Rules,'' and then look up the
entry for this document under the ``Federal Register--Environmental
Documents.'' You can also go directly to the Federal Register listings
at http://www.epa.gov/fedrgstr/.
A meeting agenda and background documents relevant to this meeting
are now available. EPA's position paper, questions to the FIFRA SAP,
and the FIFRA SAP composition (i.e., members and consultants) will be
available as soon as possible, but no later than mid-June. In addition,
the Agency may provide additional background documents as the materials
become available. You may obtain electronic copies of these documents,
and certain other related documents that might be available
electronically, from the FIFRA SAP Internet Home Page at http://
www.epa.gov/scipoly/sap.
2. In person. The Agency has established an official record for
this meeting under docket ID number OPP-2002-0083. The official record
consists of the documents specifically referenced in this notice, any
public comments received during an applicable comment period, and other
material information, including any information claimed as Confidential
Business Information (CBI). This official record includes the documents
that are physically located in the docket, as well as the documents
that are referenced in those documents. In addition, the Agency may
provide additional background documents as the material becomes
available. The public version of the official record, which includes
printed, paper versions of any electronic comments that may be
submitted during an applicable comment period, is available for
inspection in the Public Information and Records Integrity Branch
(PIRIB), Rm. 119, Crystal Mall #2, 1921 Jefferson Davis Hwy.,
Arlington, VA, from 8:30 a.m. to 4 p.m., Monday through Friday,
excluding legal holidays. The PIRIB telephone number is (703) 305-5805.
C. How May I Participate in this Meeting?
You may submit requests to present oral comments, written comments,
or requests for special seating arrangements through the mail, in
person, or electronically. Do not submit any information in your
request that is considered CBI. To ensure proper receipt by EPA, it is
imperative that you identify docket ID number OPP-2002-0083 in the
subject line on the first page of your request.
1. Oral comments. Oral comments presented at the meetings should
not be repetitive of previously submitted oral or written comments.
Although requests to present oral comments are accepted until the
date of the meeting (unless otherwise stated), to the extent that time
permits, interested persons may be permitted by the Chair of the FIFRA
SAP to present oral comments at the meeting. Each individual or group
wishing to make brief oral comments to the FIFRA SAP is strongly
advised to submit their request to one of the DFOs listed under FOR
FURTHER INFORMATION CONTACT no later than noon, eastern standard time,
Thursday, June 20, 2002, in order to be included on the meeting agenda.
The request should identify the name of the individual making the
presentation, the organization (if any) the individual will represent,
and any requirements for audiovisual equipment (e.g., overhead
projector, 35 mm projector, chalkboard). Oral comments before the FIFRA
SAP are limited to approximately 5 minutes unless prior arrangements
have been made. In addition, the speaker should bring to the meeting 30
copies of the oral comments and presentation slides for distribution to
the FIFRA SAP at the meeting.
2. Written comments. Although submission of written comments are
accepted until the date of the meeting (unless otherwise stated), the
Agency encourages that written comments be submitted no later than
noon, eastern standard time, Thursday, June 20, 2002, to provide the
FIFRA SAP the time necessary to consider and review the written
comments. There is no limit on the extent of written comments for
consideration by the FIFRA SAP. Persons wishing to submit written
comments at the meeting should contact one of the DFOs listed under FOR
FURTHER INFORMATION CONTACT and submit 30 copies.
3. Seating at the meeting. Seating at the meeting will be on a
first-come basis. Individuals requiring special accommodations at this
meeting, including wheelchair access, should contact the DFOs at least
5 business days prior to the meeting using the information under FOR
FURTHER INFORMATION CONTACT so that appropriate arrangements can be
made.
[[Page 38106]]
Contact DFO, Olga Odiott, for topic 1 and DFO, Paul Lewis for topic 2.
4. Submission of requests and written comments--a. By mail. Submit
your request or written comments to: Public Information and Records
Integrity Branch (PIRIB), Information Resources and Services Division
(7502C), Office of Pesticide Programs (OPP), Environmental Protection
Agency, Pennsylvania Ave., NW., Washington, DC 20460.
b. In person or by courier. Deliver your request or written
comments to: Public Information and Records Integrity Branch (PIRIB),
Information Resources and Services Division (7502C), Office of
Pesticide Programs (OPP), Environmental Protection Agency, Rm. 119,
Crystal Mall #2, 1921 Jefferson Davis Hwy., Arlington, VA. The PIRIB is
open from 8:30 a.m. to 4 p.m., Monday through Friday, excluding legal
holidays. The PIRIB telephone number is (703) 305-5805.
c. Electronically. You may submit your request or written comments
electronically by e-mail to: opp-docket@epa.gov. Do not submit any
information electronically that you consider to be CBI. Use WordPerfect
9.0 or ASCII file format and avoid the use of special characters and
any form of encryption. Be sure to identify by docket ID number OPP-
2002-0083. You may also file a request online at many Federal
Depository Libraries.
II. Background
A. Purpose of the Meeting
The FIFRA SAP will meet to review two topics:
1. Update the FIFRA SAP on the status of preliminary results from
cumulative risk estimates for organophosphate pesticides (OP) using
alternative models (Calendex\TM\, LifeLine\TM\, and CARES\TM\) and
similar input data and parameters.
Cumulative risk estimates for OPs derived by EPA using the
Calendex\TM\ model (Novigen Sciences, Inc.) will be compared to
preliminary results derived by The LifeLine Group using the
LifeLine\TM\ model and the Sound Science Policy Alliance (SSPA) using
the CARES\TM\ model. The LifeLine\TM\ assessments were conducted under
contract to EPA. CARES\TM\ assessments were conducted by a group of OP
registrants and their consultants (SSPA). These preliminary results
will be presented to the FIFRA SAP by EPA for informational purposes
only. The FIFRA SAP will not be asked to formally review and comment on
these preliminary results.
2. Cumulative risk assessments for organophosphate pesticides:
Susceptibility and age dependent sensitivity. The FQPA instructs EPA,
in making its ``reasonable certainty of no harm'' finding, that in
``the case of threshold effects,...an additional tenfold margin of
safety for the pesticide chemical residue and other sources of exposure
shall be applied for infants and children to take into account
potential prenatal and postnatal toxicity and completeness of data with
respect to exposure and toxicity to infants and children.'' In
implementing the FQPA safety factor provision in the context of
assessing cumulative risk, the Agency has evaluated pertinent data
concerning the potential for prenatal and postnatal effects associated
with the common mechanism of toxicity for OP pesticides (namely,
inhibition of acetylcholinesterase), the completeness of the hazard
data with respect to common mechanism of toxicity to infants and
children, and the completeness of the exposure database. The Agency
seeks the FIFRA SAP's review on the interpretation of the available
laboratory studies on cholinesterase activity in fetal, neonatal and
juvenile rats. In addition, the FIFRA SAP is asked to consider the
mechanistic basis underlying the age dependent sensitivity of young to
cholinesterase inhibition caused by OP pesticides.
B. The FIFRA SAP Report
The FIFRA SAP will prepare a report of its recommendations to the
Agency in approximately 60 days. The report will be posted on the FIFRA
SAP web site or may be obtained by contacting the Public Information
and Records Integrity Branch at the address or telephone number listed
in Unit I. of the SUPPLEMENTARY INFORMATION.
List of Subjects
Environmental protection, Organophosphate pesticides, Pesticides
and pests.
Dated: May 22, 2002.
Sherell A. Sterling,
Director, Office of Science Coordination and Policy.
[FR Doc. 02-13522 Filed 5-30-02; 8:45 am]
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