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Peer Consultation Workshop on Research Needs Related to the IRIS Draft Toxicological Review of Naphthalene

 
[Federal Register: March 8, 2005 (Volume 70, Number 44)]
[Notices]
[Page 11240-11241]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr08mr05-81]

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ENVIRONMENTAL PROTECTION AGENCY
[FRL-7882-1]

Peer Consultation Workshop on Research Needs Related to the IRIS
Draft Toxicological Review of Naphthalene

AGENCY: Environmental Protection Agency.
ACTION: Notice of peer consultation workshop.

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SUMMARY: The U.S. Environmental Protection Agency (EPA) is announcing
that the Oak Ridge Institute of Science and Education (ORISE),
Department of Energy, under an Interagency Agreement with EPA, will
organize and conduct a workshop to seek expert opinion on the research
needs related to the mode of action of the inhalation carcinogenicity
of naphthalene. Meeting participants will be provided with the ``Final
Report on the External Peer Review for the IRIS Reassessment of the
Inhalation Carcinogenicity of Naphthalene (August 2004),'' the external
review draft document entitled, ``Toxicological Review of Naphthalene:
In Support of Summary Information on the Integrated Risk Information
System (IRIS)'' (NCEA-S-1707), and a list of recent naphthalene
publications. Members of the public may attend as observers. EPA will
consider the comments and recommendations from the expert panel in
determining a future course of action for assessing potential health
risks associated with naphthalene exposure.

DATES: The workshop will begin on April 7, 2005, at 9 a.m. and end at 4
p.m. To attend the meeting, register by April 1, 2005.

ADDRESSES: The workshop will be held at the Graduate School of Public
Health, 130 DeSoto Street, Room 109 Parran Hall, University of
Pittsburgh, Pittsburgh, PA 15261. Under an Interagency Agreement
between EPA and the Department of Energy, the Oak Ridge Institute of
Science and Education (ORISE) is organizing, convening, and conducting
the workshop. To attend the meeting, register by April 1, 2005, by
contacting ORISE, P.O. Box 117, MS 17, Oak Ridge, TN 37831-0117, at
(865) 241-5784 or (865) 241-3168 (facsimile). Interested parties may
also register on-line at: http://www.orau.gov/naphthalene. Exit Disclaimer 
Space is limited, and reservations will be accepted on a first-come, 
first-served basis.
    The documents related to the workshop, ``Final Report on the
External Peer Review for the IRIS Reassessment of the Inhalation
Carcinogenicity of Naphthalene (August 2004)'', ``Draft Toxicological
Review of Naphthalene: In Support of Summary Information on the
Integrated Risk Information System (IRIS) (NCEA-S-1707),'' and ``List
of Recent Naphthalene Literature,'' are available in limited paper
copies by contacting the IRIS Hotline at (202) 566-1676 or (202) 566-
1749 (facsimile), hotline@iris.gov (e-mail). If you are requesting
paper copies, please provide your name, mailing address, and the
document title and number, if applicable. Copies are not available from
ORISE.

FOR FURTHER INFORMATION CONTACT: Questions regarding registration and
logistics should be directed to Leslie Shapard, ORISE, P.O. Box 117, MS
17, Oak Ridge, TN 37831-0117, at (865) 241-5784 or (865) 241-3168
(facsimile), shapardl@orau.gov (e-mail).
    If you have questions about the workshop documents, contact Lynn
Flowers, IRIS Staff, National Center for Environmental Assessment, 1200
Pennsylvania Avenue, NW. (8601 D), Washington, DC 20460; telephone:
202-564-1537; facsimile: 202-565-0075; flowers.lynn@epa.gov (e-mail).

SUPPLEMENTARY INFORMATION:

Integrated Risk Information System (IRIS)

    IRIS is a database that contains information on the potential
adverse human health effects that may result from chronic (or lifetime)
exposure to specific chemical substances found in the environment. The
database (available on the Internet at http://www.epa.gov/iris)
contains qualitative and quantitative health effects information for
more than 500 chemical substances that may be used to support the first
two steps (hazard identification and dose-response evaluation) of the
risk assessment process. When supported by available data, the database
provides oral reference doses (RfDs) and inhalation reference
concentrations (RfCs) for chronic health effects, and oral slope
factors and inhalation unit risks for carcinogenic effects. Combined
with specific exposure information, government and private entities use
IRIS to help characterize public health risks of chemical substances in
a site-specific situation and thereby support risk management decisions
designed to protect public health.
    EPA's IRIS program is developing a health assessment on naphthalene
carcinogenicity. A draft assessment was peer reviewed in July, 2004.
One of the topics discussed at the peer review workshop was the need
for further research to elucidate naphthalene's carcinogenic mode of
action. The Agency has decided to hold a peer consultation workshop on
this topic before determining a course of action on the IRIS assessment
of naphthalene. This action provides public notice of the workshop.

EPA's E-Docket

    EPA has established an official public docket for this action under
Docket ID No. ORD-2005-0008. The official public docket consists of the
documents specifically referenced in this action and other information
related to this action. Although a part of the official docket, the
public docket does not include Confidential Business Information (CBI)
or other information whose disclosure is restricted by statute. The
official public docket is the collection of materials that is available
for public viewing at the Office of Environmental Information (OEI)
Docket in the Headquarters EPA Docket Center, (EPA/DC) EPA West
Building, Room B102, 1301 Constitution Ave., NW., Washington, DC. The
EPA Docket Center Public Reading Room is open from 8:30 a.m. to 4:30
p.m., Monday through Friday, excluding legal

[[Page 11241]]

holidays. The telephone number for the Public Reading Room is 202-566-
1744, and the telephone number for the OEI Docket is 202-566-1752;
facsimile: 202-566-1753; or e-mail: ORD.Docket@epa.gov.
    An electronic version of the public docket is available through
EPA's electronic public docket and comment system, EPA Dockets. You may
use EPA Dockets at http://www.regulations.gov/ to access the index
listing of the contents of the official public docket. Once in the
system, select ``search,'' then key in the appropriate docket
identification number.
    Certain types of information will not be placed in the EPA Dockets.
Information claimed as CBI and other information whose disclosure is
restricted by statute, which is not included in the official public
docket, will not be available for public viewing in EPA's electronic
public docket. EPA's policy is that copyrighted material will not be
placed in EPA's electronic public docket but will be available only in
printed, paper form in the official public docket.

    Dated March 2, 2005.
Peter W. Preuss,
Director, National Center for Environmental Assessment.
[FR Doc. 05-4472 Filed 3-7-05; 8:45 am]
BILLING CODE 6560-50-P 

 
 

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