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Exposure and Dose Research Branch
Dr. Curtis C. Dary, Branch ChiefThe Exposure and Dose Research Branch (EDRB), located in Las Vegas, conducts research to define, quantify, and reduce the uncertainty associated with the exposure and risk assessment process. EDRB develops improved methods to accurately measure exposure and dose. EDRB explores the formation of multimedia, multipathway, and multiroute models to predict exposure and dose, and the design and implementation of measurement studies to increase EPA's knowledge and understanding of exposure.
This is accomplished through: Exposure Assessment Research; development of models describing and predicting Dose resulting from exposure; developing computer platforms, such as TEM (Total Exposure Model); ERDEM (Exposure-Related Dose-Estimating Model); developing enhanced Mathematical and Computational Modeling Methods; design of Exposure Field Studies; Survey Design Support; analysis of data from field studies (HEDS) and the development and application of new and innovative Field-Applicable Exposure Monitoring Technologies, such as immunoassays and biosensors.
| Visiting Las Vegas | Detailed Map of Local Las Vegas Area [PDF, 1 pp., 276 KB, About PDF] |
| Federal Staff |
Specialties |
| Dr.
Curtis C. Dary, Branch Chief |
Toxicology;
dermal exposure
assessment, Computational Toxicology |
| Mathematics;
pharmacokinetic
dose modeling; risk assessment |
|
| Chemistry;
data base management; exposure assessment field studies; quality
assurance/quality control;
HEDS |
|
| Dr. Daniel T. Chang | Computational chemistry; high performance computing; electronic structure calculations, solvation models; quantum effects, chemical dynamics; quantitative structure and activity relationships (QSAR) |
Virtual high throughput screening; molecular docking, in silico chemical genomics, computational toxicology; Modeling metabolic parameters; BBPK models of complex-phases, non-ideal materials and multi-component mixtures; QM theory-assisted structural elucidation |
|
| Chemistry;
high performance computing (HPC) applications for PBPK modeling
|
|
| Quality Assurance Branch Representative; model verification;
risk assessment |
|
| Chemical
engineering; exposure and dose modeling; cellular, immune, and
physiologic system modeling; Computational
Toxicology |
|
Computational chemistry; medicinal chemistry; 3-dimensional quantitative structure activity relationships (3D-QSAR); docking, high performance computing (HPC). |
|
| Chemistry;
biosensors |
|
| Pharmacokinetic
dose modeling (Research Triangle Park, NC); Computational
Toxicology |
|
| Ilene Sue Ruhoy, MD | Dissertation project; disposal of pharmaceuticals in the environment; accumulation and Waste of Pharmaceuticals |
Janet Barbour |
Secretary |
| Support Staff (SEEP*) |
Specialties |
| Howard
H. Weetall |
Chemistry;
biosensors |
| * SEEP-NAHE =
Senior Environmental Employment Program-National Association
of Hispanic Elderly ...more
details |