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Dr. Larry C. Butler
RESEARCH CHEMIST
Exposure and Dose Research Branch
Human Exposure and Atmospheric Sciences Division
EDUCATION/TRAINING
B.S. Chemistry, 1966, Lewis and Clark College, Portland, OR
Ph.D. Synthetic Organic Chemistry, 1972, University of Washington, Seattle, WA
PROFESSIONAL EXPERIENCE
Project Officer, NERL-HEASD-EDRB, Las Vegas, 8/95 – present
Project Officer, Contract Laboratory Program, EMSL-LV-QAD-QAB, Las Vegas, 4/83 – 8/95
Research Chemist, EPA-ORD-Environmental Research Laboratory, Gulf Breeze, FL, 1981-1983
Research Chemist, EPA, Pesticides Research Branch, Wenatchee, WA, 1974-1981
SELECTED AWARDS AND HONORS
U.S. EPA\ORD Silver Medal: Quality Assurance for the Contract Laboratory Program, 1984
U.S. EPA\ORD\NERL Awards Board, 2001-Present
U.S. EPA\ORD\ Sustained Superior Performance, 2005
U.S. EPA\ORD\ Sustained Superior Performance, 2004
Phi Beta Kappa\1966
SELECTED PUBLICATIONS: 1966 - present, (18 listed from 127 total publications)
Edo D. Pellizzari and Larry C. Butler, "Arizona Border Study - Analysis of Food Samples." Final Report, Exposure & Dose Research Branch, Human Exposure and Atmospheric Sciences Division, Las Vegas, NV, February 19, 1999.
Kent W. Thomas, Edo D. Pellizzari, and Larry C. Butler, "NHEXAS Comparability Studies." Final Report, Exposure & Dose Research Branch, Human Exposure and Atmospheric Sciences Division, Las Vegas, NV, September 22, 1997.
Dawn M. Boyer, Daniel C. Hillman, David E. Dobb, and Larry C. Butler, "Superfund Sample Preparation for Metals Analysis - Is a Separate Sample Necessary for Furnace AAS?," The Pittsburgh Conference Abstracts, Paper No. 345P, March (1995).
Laurine J. Ottmar, Dawn M. Boyer, Daniel C. Hillman, David E. Dobb, and Larry C. Butler, "An Evaluation of a New Trace Level ICP-MS Instrument for Determination of Furnace AAS Analytes under the Proposed Superfund Low Concentration SOW." The Pittsburgh Conference Abstracts, Paper No. 001P, March (1995).
D. E. Dobb, R. C. Metcalf, R. W. Gerlach, and L. C. Butler, "Optimizing Reactions for Preserving Mercury with Gold Chloride in environmental Water Samples," Emerging Technologies in Hazardous Waste Management VI, Vol. 2, pp. 1438-1441, September (1994).
David E. Dobb, J. T. Rowan, and D. Cardenas, and L. C. Butler, "Determination of Mercury by ICP-MS." U.S. Environmental Protection Agency, Las Vegas, NV 89119, "The 10th Annual Waste Testing and Quality Assurance Symposium, Washington, DC, July 11-15 (1994), pages 387-394.
D. C. Hillman, D. M. Boyer, and L. C. Butler, "An Evaluation of GFAA QC Criteria: Duplicate Injection Requirement." The 10th Annual Waste Testing and Quality Assurance Symposium, Washington, DC, July 1994.
Larry C. Butler, "Quality Assurance Research for Superfund." Quality Assurance and Methods Development Division (reorganized as the Analytical Sciences Division), Environmental Monitoring Systems Laboratory, Las Vegas, NV, EPA/600/X-94/022, (FY93), June 1994.
Larry C. Butler, "Quality Assurance Research for Superfund." Quality Assurance and Methods Development Division, Environmental Monitoring Systems Laboratory, Las Vegas, NV, EPA/600/X-93/065, (FY92), July (1993).
Larry C. Butler and Kenneth W. Brown, Robotics Technology in Environmental Sample Preparation, Fact Sheet, Environmental Protection Agency, Environmental Monitoring Systems Laboratory, Las Vegas, NV, August (1992).
Larry C. Butler, Daniel Hillman, and Piotr Nowinski, "Robotic - Microwave Digestion System for the Contract Laboratory Program." Proceedings: 201st National American Chemical Society Meeting, Vol. 31, No. 1, April (1991).
Larry C. Butler, John Nocerino, Edward Kantor, Michael Hiatt, Jimmie Petty, Robert Newberry, and Harold Vincent, "Quality Assurance in Support of Superfund." Quality Assurance and Methods Development Division, Environmental Monitoring Systems Laboratory, Las Vegas, NV, EPA/600/X-90/033, (FY89), February (1990).
SELECTED PRESENTATIONS
“Learning from the East in the EPA,” by Larry Butler, Drew Pilant, Debdas Mukerjee, Edwin Furtaw, Amy Zhao, William Engelmann, Armah de la Cruz, and Fred Kawahara, Earth Day Presentation, University of Nevada - Las Vegas, April 22, 2003.
"WinCADRE Inorganic (Windows Computer-Aided Data Review and Evaluation)," Larry C. Butler, William A. Coakley, Vijaya D. Dandge, and J. Randy Caldwell, Pittsburgh 2001 Conference, New Orleans, LA, March 3-10, 2001.
"WinCADRE Volatiles (Computer Aided-Data Review and Evaluation)," Larry C. Butler, William A. Coakley, Vijaya D. Dandge, John R. Caldwell, and Vasu D. Desican, Pittsburgh 2000 Conference, New Orleans, LA, March 12-17, 2000.
S. C. Hern, G. L. Robertson, L. C. Butler, W. H. Engelmann, E. J. Kantor, J. J. Quackenboss, J. V. Behar, and M. D. Pandian, "Reaching THERdbASE in Human Exposure Research." The 214th American Chemical Society Meeting, September 7-11, Las Vegas, NV (1997).
Larry C. Butler and K. W. Thomas, "National Human Exposure Assessment Survey (NHEXAS) Interlaboratory Comparability Study." Gulf Coast Conference, September 8-12, Houston, TX (1997).
J. M. Kaushik, D. K. Dandge, D. H. Hewetson, F. C. Garner, K. R. York, and L. C. Butler, "Diagnose: A System for Evaluation of Semi-Volatile Organic Analyses." Division of Environmental Chemistry, American Chemical Society, Orlando, FL (1996).
NARRATIVE
Dr. Larry C. Butler received multi-disciplinary training in various branches of chemistry leading to a research and teaching career and came to EPA as a Research Pesticide Chemist in 1974. His publications included environmental studies of pesticides by taking his own human exposure field samples, working these up in the laboratory and doing his own instrumental analyses. He published 127 papers and presentations. Later, Dr. Butler spent many years as a Quality Assurance Expert for the EPA Contract Laboratory Program, which included 128 laboratories. Dr. Butler performed on-site laboratory evaluations and was the Supervisor of Performance Evaluation Program, which provided Performance Evaluation (PE) samples, audit, and method research as one phase of the EMSL-LV Quality Assurance support of the Office of Emergency and Remedial Response (OERR), Superfund Contract Laboratory Program (CLP). He managed a program staff of 17, which included chemists, data auditors, statisticians, and clerical aides. Organic, inorganic, and dioxin Performance Evaluation samples were provided for CLP laboratories nationwide with the assistance of the EPA Regions. Data returned were scored statistically and audited for deliverables. Results were provided to Superfund (OERR), Regions and states, and the contract laboratories for corrective actions. PE results were also provided to assist on-site teams. Dr. Butler served as an on-site laboratory evaluation Team Leader. Examples of methods R&D included laboratory robotics, the development of ICP-MS for the CLP, extraction/pH studies, metals microwave digestion studies, and statistical analyses.
His last 15 years at EPA produced over 50 additional publications in Quality Assurance and Analytical Chemistry, while being an expert Project Officer for the Quality Assurance and Methods Development Division, Quality Assurance Research Branch, which was later changed to the Human Exposure and Atmospheric Sciences Division and the Exposure and Dose Research Branch.
The ORD reorganization in August 1994 reformulated the research at EPA Las Vegas and Dr. Butler, as Project Leader, entered the Human Health research area in the new Human Exposure Research Branch. He took on the work that had been started on the Total Human Exposure Research data base and Advanced Simulation Environment (THERdbASE) as well as performing expert Public Outreach as part of the Web Response Team.
Recently, he has collaborated with a Region 4 coworker on a Triad Fact Sheet regarding only the analytical chemistry methods for this Brownfield site.
Very recently, he has provided database development and management oversight for “Models and Modeling Methods for Assessing Human Exposure and Dose to Toxic Chemicals and Pollutants,” using ERDEM. He has managed a biomarker database in SPSS where exposure-dose interpretations in PBPK/PD modeling are supported.