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Dr. Andrew B. Lindstrom
RESEARCH PHYSICAL SCIENTIST
Exposure Measurements and Analysis Branch
Human Exposure and Atmospheric Sciences Division
EDUCATION/TRAINING
Ph.D., Environmental Health Sciences,The University of North Carolina at Chapel Hill, 1999
M.S., Biological Sciences, Wright State University, Dayton, Ohio, 1986
B.S., Biology, Winona State University, Winona, Minnesota, 1983
PROFESSIONAL EXPERIENCE
Research Physical Scientist, USEPA, ORD, NERL, HEASD, EMAB, RTP, NC; 1990 to present
Science Fellow, US Department of State, American Embassy, Tokyo, Japan, Oct. 2004 – Jan. 2005
Senior Scientist with NSI Technology Services Corporation, RTP, NC 1989 - 1990
Air Pollution Control Analyst for the Regional Air Pollution Control Agency, Dayton, OH 1986 -1989
SELECTED AWARDS AND HONORS
2008 ORD Honor Award, PFC research Team, for developing and establishing new methods for the measurement of the perfluorinated compounds (PFCs) in environmental and biological media, June 26, 2009.
2008 Scientific and Technological Achievement Award (STAA) Level I Award for “A Team Contribution to the Understanding of Early-Life Health Effects Following Perinatal Exposure to PFOA in Mice”.
Special Accomplishment Recognition, PFC-related research, August, 2007
ORD Honor Award, Perfluorinated Chemical Research Team, September 28, 2006.
Special Accomplishment Recognition, PFC-related research, September, 2006.
Special Accomplishment Recognition, PFC-related research, August 8, 2006.
Appointed to the Board of the International Association of Breath Research, Vienna, Austria, May, 2005
Special Accomplishment Recognition, September, 2004
Award for meritorious performance, April, 2004
Special Accomplishment Recognition, July, 2003
Award for meritorious performance, August, 2002
Member of the European Respiratory Society Task Force on Exhaled Biomarkers, Berlin, Sept. 2001.
ORD Long-Term Training/Sabbatical Program in 1995
SELECTED PUBLICATIONS (20 out of 38 from 1989 to present)
C. Lau, A.B. Lindstrom, and J. Seed, (2009) PFAA days II meeting report and highlights, Reproductive Toxicology, Jun;27(3-4):429-34
S.E. Fenton, J.L. Reiner, S.F. Nakayama, A.D. Delinsky, J.P. Stanko, E.P. Hines, S.S. White, A.B. Lindstrom, M.J. Strynar, and S.E. Petropoulou, (2009) Analysis of PFOA in Dosed CD-1 Mice Part 2: Disposition of PFOA in tissues and fluids from pregnant and lactating mice and their pups, Reproductive Toxicology. Jun;27(3-4):365-72.
J.L. Reiner, S.F. Nakayama, A.D. Delinsky, J.P. Stanko, S.E. Fenton, A.B. Lindstrom, and M.J. Strynar, (2008) Analysis of PFOA in dosed CD1 mice: Part 1. Methods development for the analysis of tissue and fluids from lactating mice and their pups, Reproductive Toxicology, Jun;27(3-4):360-4.
I. Lou, J.F. Wambaugh, C. Lau, R.G. Hanson, A.B. Lindstrom, M.J. Strynar, R. D. Zehr, R. W. Setzer, and H. A. Barton (2008) Modeling single and repeated dose pharmacokinetics of PFOA in mice, Toxicological Sciences, 107 (2):331-41.
X.Ye, H.L. Schoenfuss, N.D. Jahns, A.D. Delinsky, M.J. Strynar, J. Varns, S.F. Nakayama, and A.B. Lindstrom, (2008) Perfluorinated Compounds in Common Carp (Cyprinus carpio) Fillets from the Upper Mississippi River, Environment International, 34 (7) 932-938.
X.Ye, M.J. Strynar, J. Varns, S. Nakayama, L. Helfant, J. Lazorchak, and A.B. Lindstrom, (2008) Perfluorinated Compounds in Whole Fish Homogenates from the Ohio, Missouri, and Upper Mississippi Rivers, USA. Environmental Pollution, 156 (3) 1227-1232.
B.D. Abbott, C.J. Wolf, K.P. Das, R.D. Zehr, J.E. Schmid, A.B. Lindstrom, M.J. Strynar, C. Lau, (2008) Developmental toxicity of perfluorooctane sulfonate (PFOS) is not dependent on expression of peroxisome proliferator activated receptor-alpha (PPARa) in the mouse, Reproductive Toxicology, Jun;27(3-4):258-65.
M.J. Strynar and A.B. Lindstrom, (2008) Perfluorinated Compounds in House Dust from Ohio and North Carolina, USA, Environmental Science and Technology, 42(10):3751-3756.
D.C. Wolf, T. Moore, B.D. Abbott, M.B. Rosen, K. Das, R.D. Zehr, A.B. Lindstrom, M.J. Strynar, and C. Lau, (2008) Comparative Hepatic Effects of Perfluorooctanoic Acid and WY 14,643 in PPARα-Knocked Out and Wild-type Mice, Toxicologic Pathology, 36(4) 632-639
S. Nakayama, M. Strynar, L. Helfant, P. Egeghy, X.Ye, and A.B. Lindstrom. 2007. Perfluorinated Compounds in the Cape Fear Drainage Basin in North Carolina. Environmental Science and Technology, 41:5271-5276.
B.D. Abbott, C.J. Wolf, J.E. Schmid, K. P. Das, R.D. Zehr, L. Helfant, S. Nakayama, A.B. Lindstrom, M.J. Strynar, C. Lau. 2007. Perfluorooctanoic Acid (PFOA)-induced developmental toxicity in the mouse is dependent on expression of Peroxisome Proliferator Activated Receptor-alpha (PPARa),Toxicological Sciences. Aug; 98(2):571-81.
S.S. White, A.M. Calafat, Z. Kuklenyik, L. Villanueva, D. Zehr, L. Helfant, M.J. Strynar, A. B. Lindstrom, J. R. Thibodeaux, C. Wood, and S.E. Fenton. 2006. Gestational PFOA Exposure of Mice is Associated with Altered Mammary Gland Development in Dams and Female Offspring. Toxicological Sciences, Mar; 96(1):133-44.
J.H. Offenberg, H.M. Stapleton, M.J. Strynar and A.B.Lindstrom (2006), Polybrominated Diphenyl Ethers in US soils. Organohalogen Compounds vol. 68, pp 1816-1819.
C. Lau, J.R. Thibodeaux, R.G. Hanson, M.G. Narotsky, J.M. Rogers, A.B. Lindstrom, and M.J. Strynar. 2006. Effects of perfluorooctanoic acid exposure during pregnancy in the mouse. Toxicological Sciences, 90(2):510-519.
A.B. Lindstrom, Recent Developments in Exhaled Breath Analysis and Human Exposure Research, Book Chapter in “Breath Analysis for Medical Diagnosis and Therapeutic Monitoring” edited by Anton Amann and David Smith, World Scientific (Singapore), May 2005.
S. Waidyanatha, M.A. Troester, A.B. Lindstrom, and S.M. Rappaport. 2002. Measurement of hemoglobin and albumin adducts of naphthalene-1,2-oxide, 1,2-naphthoquinone and 1,4-naphthoquinone after administration of naphthalene to F344 rats. Chemico-Biological Interactions, 141(3): 189-210.
M.A. Troester, A.B. Lindstrom, S. Waidyanatha, L.L. Kupper, and S.M. Rappaport. 2002. Stability of hemoglobin and albumin adducts of naphthalene oxide, 1,2-naphthoquinone, and 1,4-naphthoquinone.Toxicological Sciences, 68 (2): 314-321.
A.B. Lindstrom and J.D. Pleil. 2002. A review of the USEPA’s single breath canister (SBC) method for exhaled volatile organic biomarkers. Invited manuscript, Biomarkers, 7 (3):189-208.
A.B. Lindstrom and J.D. Pleil, Volatile organic compounds as exposure biomarkers. 2002. Book Chapter in "Disease Markers in Exhaled Breath; IOS Press, Amsterdam, Berlin, Oxford, Tokyo, Washington, DC; editors: N. Marczin & M.H. Yacoub; (first edition, September 25, 2002).
SELECTED PRESENTATIONS
A.B. Lindstrom, M.J. Strynar, S.F. Nakayama, A.D. Delinsky, and L. McMillian “Human Exposure to Persistent Perfluorinated Compounds” and chair session on PFC research, Japanese Society of Toxicology (JSOT) meeting, Morioka, Iwate, Japan, July, 2009.
A.B. Lindstrom, M.J. Strynar, S. Nakayama, A. Delinsky, J. Reiner, and L. Helfant, “U.S. Environmental Protection Agency Human Exposure Research for the Perfluorinated Compounds” Korean Society for Environmental Analysis (KSEA) meeting on November 6, 2008, Jeju, Korea.
A.B. Lindstrom, M.J. Strynar, S. Nakayama, A. Delinsky, J. Reiner, and L. Helfant, “U.S. Environmental Protection Agency Human Exposure Research for the Perfluorinated Compounds” Emerging Environmental Pollutants and POPs”, November 7 – 8, Dioxin Research Center of Pukyuong National University, Busan, Korea.
A.B. Lindstrom, M.J. Strynar, S. Nakayama, S. Petropoulou, A. Delinsky, J. Reiner, L. Helfant, and J. Varns, “Worldwide Interest in Perfluorinated Organic Compound Contamination” invited lecture at Agilent Technologies Japan, Hachioji, Tokyo Japan, July 2, 2007.
A.B. Lindstrom, M.J. Strynar, S. Nakayama, S. Petropoulou, A. Delinsky, J. Reiner, L. Helfant, and J. Varns, “Human Exposures to Persistent Perfluorinated Compounds in the Environment” invited lecture at the 34rd annual meeting of the Japanese Society of Toxicology, Tokyo, June 28, 2007.
A.B. Lindstrom and M. Strynar, Perfluorinated Organic Compound Exposure Assessment Research, Invited lecture, International Conference on Environmental and Genetical Damage, November 3 - 6, 2005, Chongqing, China.
A.B. Lindstrom and M. Strynar, Perfluorinated Organic Compound Exposure Assessment Research, Invited lecture, National Institute of Environmental Studies, Tsukuba, Japan, October 31, 2005.
A.B. Lindstrom, Recent Developments in Exhaled Breath Analysis and Human Exposure Assessment Research, Invited Lecture, at Breath Analysis for Medical Diagnosis and Therapeutic Monitoring,Innsbruck, Austria, May 26 -28, 2005.
A.B. Lindstrom and M. Strynar, Persistent Perfluorinated Organic Compounds Method Development Research at the U.S. Environmental Protection Agency, Invited Lecture, Center for Marine Environmental Studies Ehime University Matsuyama, Japan, January 11, 2005.
A.B. Lindstrom and M. Strynar, Persistent Perfluorinated Compounds in the Environment: a Brief Introduction to this Important New Class of Pollutants, Invited lecture, National Cancer Center, Research Center for Cancer Prevention and Screening, Epidemiology and Prevention Division, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan, December 21, 2004
A.B. Lindstrom and M. Strynar, Persistent Perfluorinated Organic Compounds Method Development Research at the U.S. Environmental Protection Agency, Invited Lecture, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan, December 9, 2004
A.B. Lindstrom and M. Strynar,Persistent Perfluorinated Compounds in the Environment: a New Challenge for the U.S. Environmental Protection Agency, Tokyo American Center, Embassy of the United States, Tokyo, Japan, Dec. 2, 2004.
NARRATIVE
Current research activities involve methods development for the detection of persistent perfluorinated organic compounds (PFCs) in biological and environmental media.