Integrated Risk Information System (IRIS)
EPA's Integrated Risk Information System (IRIS) is a human health assessment program that evaluates information on health effects that may result from exposure to environmental contaminants. Through the IRIS Program, EPA provides the highest quality science-based human health assessments to support the Agency's regulatory activities. The IRIS database is web accessible and contains information on more than 550 chemical substances. Learn more.
What's New in IRIS
- 5/14: New Schedule for IRIS Acrylonitrile Assessment Announced
- 5/7: IRIS announces the IRIS 2012 agenda and is requesting scientific information on health effects that may result from exposure to the chemical substances on this agenda, including assessments that EPA is starting this year. [Federal Register Notice May 7, 2012]
- 4/6: IRIS announces the availability of literature searches for acetaldehyde (75-07-0) and 1,2,3-trimethlybenzene (526-73-8) and ask the public for any additional scientific information on health effects that may result from exposure to these chemical substances.
- 3/8: Update on Ramazzini Institute data in IRIS assessments
- 2/28: New Schedule for IRIS Hexavalent Chromium Assessment Announced
- 2/21: A new Summary for Tetrahydrofuran and a new accompanying Toxicological Review (PDF) (207 pp, 1.22M) have been added to the IRIS website. The Interagency Science Discussion Draft of the Tetrahydrofuran IRIS assessment has also been released.
- 2/17: A new Summary for 2,3,7,8-Tetrachlorodibenzo-p-dioxin and a new accompanying Support Document have been added to the IRIS Web site. The Interagency Science Discussion Draft of the 2,3,7,8-Tetrachlorodibenzo-p-dioxin IRIS assessment has also been released.
- 2/10: A new Summary for Tetrachloroethylene (Perchloroethylene) and a new accompanying Toxicological Review (PDF) (1,077 pp, 14.4M) have been added to the IRIS Web site. The Interagency Science Discussion Draft of the Tetrachloroethylene (Perchloroethylene) IRIS assessment has also been released.
- 02/06: External Peer Review Meeting for Toxicological Review of Vanadium Pentoxide (External Review Draft) scheduled for March 7, 2012. [Federal Register Feb 6, 2012]
Draft Assessments under External Peer Review
- Biphenyl (09/30)
- Vanadium Pentoxide (09/30)
- 1,4-Dioxane (Inhalation) (09/09)
- n-Butanol (09/08)
- Libby Amphibole Asbestos (08/25)
- Acrylonitrile (06/30)
- Methanol (Non-Cancer) (04/18)
Recent Final Assessments
- Tetrahydrofuran (02/21)
- 2,3,7,8-Tetrachlorodibenzo-p-dioxin (02/17)
- Tetrachloroethylene (Perchloroethylene) (02/10)
- Dichloromethane (11/18)
- Trichloroacetic acid (09/30)
- Trichloroethylene (09/28)
- Hexachloroethane (09/23)
- Urea (07/13)