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Inorganic Arsenic Meetings & Webinars

UPDATE: NRC released an Interim Report on inorganic arsenic - November 7, 2013.

EPA is announcing a series of public meetings and webinars on the Integrated Risk Information System (IRIS) Toxicological Review of Inorganic Arsenic. These events are designed to inform the planning for EPA’s toxicological review of chronic exposure to inorganic arsenic (iAs) (cancer and non-cancer effects), which EPA intends to post to the Integrated Risk Information System (IRIS) database.

  • Janice Lee, co-Chemical Manager
    Email: Lee.JaniceS@epa.gov
    Phone: (919) 541-9458
  • John Cowden, co-Chemical Manager
    Email: Cowden.John@epa.gov
    Phone: (919) 541-3667
Opportunities for Public Engagement

Or visit the links below for additional opportunities to get involved.

NRC Guidance and Review
of EPA's IRIS Assessment of Inorganic Arsenic

NRC iAs Project Information page Exit EPA disclaimer

Provide feedback on this project Exit EPA disclaimer

Start date Jul 17, 2012

Calendar of Events

There are no scheduled meetings at this time

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Schedule Dates


EPA’s Integrated Risk Information System (IRIS) Program is developing an updated assessment of inorganic arsenic.

What is arsenic? Arsenic is a metal that occurs naturally in the Earth's crust. It can leach from soil and rock into water. In the United States, arsenic is commonly found in groundwater in the southwest. Additionally, parts of New England, Michigan, Wisconsin, Minnesota, and the Dakotas have significant concentrations of naturally occurring arsenic.  Arsenic can also be released into the environment through industrial processes and emissions. Arsenic is used for hardening copper and lead alloys; in glass manufacturing as a decolorizing and refining agent; as a component of electrical devices; in the semiconductor industry; and as a catalyst in the production of ethylene oxide.  Arsenic compounds are also used in the textile industries, medicines, pesticides, pigments, and wood preservatives.

IRIS Assessment Development: Below is a list of milestones and associated products for developing the updated IRIS assessment of inorganic arsenic.

Step 1: Draft Development
  • EPA internal meeting on planning and scoping for the development of the inorganic arsenic IRIS assessment (Sep 2012)
  • EPA public meeting on planning and scoping for the development of the inorganic arsenic IRIS assessment (Jan 8-9, 2013)
  • EPA Arsenic Webinar Series

EPA History of Arsenic Assessments: EPA published an IRIS assessment of inorganic arsenic in 1988 and began updating the assessment in 2003. The update implemented recommendations from two National Research Council (NRC) reports (1999 and 2001) that evaluated EPA’s drinking water standards for inorganic arsenic. In 2005, the IRIS Program released a draft arsenic assessment (focused on cancer health effects following oral exposure to inorganic arsenic) for public comment and review by EPA’s Science Advisory Board (SAB). The SAB provided recommendations in 2007, and in 2010, EPA released a revised draft inorganic arsenic assessment (focused on cancer health effects following oral exposure to inorganic arsenic) for public comment and review by the SAB. In 2011, the SAB provided comments and recommendations on the 2010 draft. 

EPA is now working to develop an updated IRIS assessment of inorganic arsenic (focused on both cancer and noncancer health effects). EPA held an internal planning and scoping meeting (September 2012) and a public stakeholder workshop on planning and scoping (January 2013) to receive input from EPA program and regional offices and the public on their needs, the current state of the science for inorganic arsenic, and the potential impacts of an inorganic arsenic assessment.  To inform the development of the draft assessment, the NRC will hold a public workshop on scientific issues that may influence the health assessment of the cancer and noncancer effects of inorganic arsenic.  When a draft assessment has been developed, EPA will submit it for peer review by the NRC.

Providing Comments: If you would like to provide additional comments- outside the events listed on this web site, please use the IRIS Public Meetings Comment & Feedback Form. If you want to be contacted with a reponse, please include your full name; company/organization name; title; affiliation; sponsoring organization, if any; email address; and phone number.

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