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IRIS Bimonthly Public Meeting (October 2013)

UPDATE: Due to the Federal Government shutdown, the IRIS Bimonthly Public Meeting originally scheduled for October 23rd has been cancelled. The chemicals scheduled for discussion at the October meeting have been added to the agenda for the next IRIS Bimonthly Public Meeting scheduled for December 12-13, 2013.

EPA originally announced a meeting to be held October 23-24, 2013, this was cancelled due to the Government shutdown and rescheduled to December 12-13, 2013. This meeting was planned to provide an opportunity for public input and discussion on preliminary materials for IRIS chemicals prior to the development of the assessments for the following chemicals:

This meeting would have also given an opportunity for the public to provide input and discussion on the draft assessment and charge to the peer review panel prior to external peer review for the following chemical:

Meeting Documents:

For 3 new chemicals, EPA has prepared draft literature searches and associated search strategies, evidence tables, and exposure response arrays for these chemicals to obtain input from stakeholders and the public prior to developing the draft IRIS assessments. Specifically, EPA is interested in comments on the following:

The literature search strategy, which describes the processes for identifying scientific literature (referred to as a systematic review of the scientific literature), contains the studies that EPA considered and selected to include in the evidence tables. The preliminary evidence tables and exposure-response arrays present the key study data in a standardized format. The evidence tables summarize the available critical scientific literature. The exposure-response figures provide a graphical representation of the responses at different levels of exposure for each study in the evidence table.

For 1 chemical, EPA has recently released a draft Toxicological Review and draft charge to the peer review panel for public review and comment. EPA is interested in comments on these documents prior to the external peer review of this assessment.

The chemicals and associated materials under discussion include:


ethyl tert-butyl ether (ETBE) - Chemical Manager: Keith Salazar


tert-butyl alcohol (tert-butanol) - Chemical Manager: Janice Lee


hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) - Chemical Manager: Louis D'Amico


ethylene oxide (EtO) - Chemical Manager: Jennifer Jinot

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