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Chlorpyrifos (CASRN 2921-88-2)

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Chlorpyrifos; CASRN 2921-88-2

Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data, as outlined in the IRIS assessment development process. Sections I (Health Hazard Assessments for Noncarcinogenic Effects) and II (Carcinogenicity Assessment for Lifetime Exposure) present the conclusions that were reached during the assessment development process. Supporting information and explanations of the methods used to derive the values given in IRIS are provided in the guidance documents located on the IRIS website.

STATUS OF DATA FOR Chlorpyrifos

File First On-Line 01/31/1987

Category (section)
Status
Last Revised
Oral RfD Assessment (I.A.) message 03/24/2011
Inhalation RfC Assessment (I.B.) message
Carcinogenicity Assessment (II.) message

_I.  Chronic Health Hazard Assessments for Noncarcinogenic Effects

_I.A. Reference Dose for Chronic Oral Exposure (RfD)

Substance Name — Chlorpyrifos
CASRN — 2921-88-2
Last Revised — 03/24/2011

Not available at this time.

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_I.B. Reference Concentration for Chronic Inhalation Exposure (RfC)

Substance Name — Chlorpyrifos
CASRN — 2921-88-2

Not available at this time.

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_II. Carcinogenicity Assessment for Lifetime Exposure

Substance Name — Chlorpyrifos
CASRN — 2921-88-2

This substance/agent has not undergone a complete evaluation and determination under US EPA's IRIS program for evidence of human carcinogenic potential.

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_III. [reserved]
_IV. [reserved]
_V. [reserved]


_VI. Bibliography

None.

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_VII.  Revision History

Substance Name — Chlorpyrifos
CASRN — 2921-88-2

Date
Section
Description
03/01/1988 I.A.5. Core grades added
11/01/1989 VI. Bibliography on-line
01/01/1992 IV. Regulatory actions updated
04/01/1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
02/22/2001 I.A., II. This chemical is being reassessed under the IRIS Program.
02/09/2004 I.A., II. This chemical is no longer being reassessed under the IRIS Program. See Federal Register February 9, 2004 (Volume 69, Number 26).
03/24/2011 I.A. The RfD for this chemical was removed.

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_VIII. Synonyms

Substance Name — Chlorpyrifos
CASRN — 2921-88-2
Last Revised — 01/31/1987

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