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Formic acid (CASRN 64-18-6)

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0055

Formic acid; CASRN 64-18-6

Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data, as outlined in the IRIS assessment development process. Sections I (Health Hazard Assessments for Noncarcinogenic Effects) and II (Carcinogenicity Assessment for Lifetime Exposure) present the conclusions that were reached during the assessment development process. Supporting information and explanations of the methods used to derive the values given in IRIS are provided in the guidance documents located on the IRIS website.

STATUS OF DATA FOR Formic acid

File First On-Line 01/31/1987

Category (section)
Status
Last Revised
Oral RfD Assessment (I.A.) withdrawn 02/01/1996
Inhalation RfC Assessment (I.B.) no data  
Carcinogenicity Assessment (II.) no data 10/01/1991

_I.  Chronic Health Hazard Assessments for Noncarcinogenic Effects

_I.A. Reference Dose for Chronic Oral Exposure (RfD)

Substance Name — Formic acid
CASRN — 64-18-6

The RfD for formic acid has been withdrawn on 12/01/1990 pending further review by the RfD Work Group.

Screening-Level Literature Review Findings — A screening-level review conducted by an EPA contractor of the more recent toxicology literature pertinent to the RfD for Formic acid conducted in September 2002 did not identify any critical new studies. IRIS users who know of important new studies may provide that information to the IRIS Hotline at hotline.iris@epa.gov or (202)566-1676.

EPA Contacts:

Please contact the IRIS Hotline for all questions concerning this assessment or IRIS, in general, at (202)566-1676 (phone), (202)566-1749 (FAX) or hotline.iris@epa.gov (internet address).

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_I.B. Reference Concentration for Chronic Inhalation Exposure (RfC)

Substance Name — Formic acid
CASRN — 64-18-6

Not available at this time.

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_II.  Carcinogenicity Assessment for Lifetime Exposure

Substance Name — Formic acid
CASRN — 64-18-6

Not available at this time.

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_III.  [reserved]
_IV.  [reserved]
_V.  [reserved]


_VI.  Bibliography

Substance Name — Formic acid
CASRN — 64-18-6

Not available at this time.

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_VII.  Revision History

Substance Name — Formic acid
CASRN — 64-18-6

Date
Section
Description
03/31/1987 I.A.6. Documentation corrected
03/01/1988 I.A.1. Critical effect revised
03/01/1988 I.A.2. Text added paragraph 1
12/01/1990 I.A. Oral RfD withdrawn pending further review
10/01/1991 II. Carcinogenicity assessment now under review
01/01/1992 IV. Regulatory action updated
08/01/1995 I.A., II. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
02/01/1996 I.A. Contact changed
04/01/1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
12/03/2002 I.A. Screening-Level Literature Review Findings message has been added.

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_VIII.  Synonyms

Substance Name — Formic acid
CASRN — 64-18-6
Last Revised — 01/31/1987

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