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Dicofol (CASRN 115-32-2)

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0324

Dicofol; CASRN 115-32-2

Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data, as outlined in the IRIS assessment development process. Sections I (Health Hazard Assessments for Noncarcinogenic Effects) and II (Carcinogenicity Assessment for Lifetime Exposure) present the conclusions that were reached during the assessment development process. Supporting information and explanations of the methods used to derive the values given in IRIS are provided in the guidance documents located on the IRIS website.

STATUS OF DATA FOR Dicofol

File First On-Line 08/22/1988

Category (section)
Status
Last Revised
Oral RfD Assessment (I.A.) no data  
Inhalation RfC Assessment (I.B.) no data  
Carcinogenicity Assessment (II.) withdrawn 07/01/1993

_I.  Chronic Health Hazard Assessments for Noncarcinogenic Effects

_I.A. Reference Dose for Chronic Oral Exposure (RfD)

Substance Name — Dicofol
CASRN — 115-32-2

Not available at this time.

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_I.B. Reference Concentration for Chronic Inhalation Exposure (RfC)

Substance Name — Dicofol
CASRN — 115-32-2

Not available at this time.

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_II.  Carcinogenicity Assessment for Lifetime Exposure

Substance Name — Dicofol
CASRN — 115-32-2

The carcinogen assessment summary for this substance has been withdrawn pending further review by the CRAVE Agency Work Group.

Agency Work Group Review — 06/03/1987, 06/24/1987, 08/05/1987, 12/04/1991, 06/02/1992

Screening-Level Literature Review Findings — A screening-level review conducted by an EPA contractor of the more recent toxicology literature pertinent to the cancer assessment for Dicofol conducted in September 2002 did not identify any critical new studies. IRIS users who know of important new studies may provide that information to the IRIS Hotline at hotline.iris@epa.gov or (202)566-1676.

EPA Contacts:

Please contact the IRIS Hotline for all questions concerning this assessment or IRIS, in general, at (202)566-1676 (phone), (202)566-1749 (FAX) or hotline.iris@epa.gov (internet address).

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_III.  [reserved]
_IV.  [reserved]
_V.  [reserved]


_VI.  Bibliography

Substance Name — Dicofol
CASRN — 115-32-2

Not available at this time.

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_VII.  Revision History

Substance Name — Dicofol
CASRN — 115-32-2

Date
Section
Description
08/22/1988 II. Carcinogen summary on-line
01/01/1990 VI. Bibliography on-line
01/01/1992 II. Carcinogen assessment noted as pending change
01/01/1992 IV. Regulatory Action section on-line
04/01/1992 II. Carcinogen assessment withdrawn pending further review
04/01/1992 IV. Withdrawn; no assessments on-line
04/01/1992 VI. Bibliography withdrawn; no assessments on-line
07/01/1992 II. Work group review dates added
07/01/1993 II. EPA contact changed
08/01/1995 II., IV.,VI. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
04/01/1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
12/03/2002 II. Screening-Level Literature Review Findings message has been added.

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_VIII.  Synonyms

Substance Name — Dicofol
CASRN — 115-32-2
Last Revised — 08/22/1988

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