Chemical Prioritization | Community Practice | Research Activities | National Center for Computational Toxicology | US EPA

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EPA Communities of Practice
Presentation Documents

Community of Practice

Chemical Prioritization
- Improved quantitative models of chemical toxicity based on combined application of chemical and biological molecular descriptors HaoZhu and Alexander (09/24/09) (ppt, 50 pp. 2.1 MB)
- Developing Predictive Bioactivity Signatures of Carcinogenesis Using ToxCast HTS Data (09/14/09) (pdf, 31 pp. 1.53 MB)
- A Tiered Approach for the Use of Non-Testing Methods in the Regulatory Assessment of Chemicals (06/24/09) (ppt, 37 pp. 2.1 MB)
- The U.S. EPA's 2006 Inventory Update Reporting (IUR) Data on Chemical Substances (5/27/09) (pdf, 20 pp. 238 KB)
- Is ChAMP a Winning Strategy? (4/22/09) (pdf, 37 pp. 247 KB)
- The ToxCast 320 Chemical Library in Cultures of Primary Human Hepatocytes (11/18/08) (pdf, 40 pp. 4.04 MB)
- The ToxCast Chemical Universeand ACToR (10/17/08) (ppt, 23 pp. 1.34 MB)
- Screening for Chemical Effects on Neuronal Proliferation and Neurite Outgrowth Using High-Content/High-Throughput Microscopy (9/25/08) (pdf, 23 pp. 1.75 MB)
- Chemical Modulation of Gap Junctional Intercellular Communication in Toxicology (8/25/08) (pdf, 41 pp. 25.4 MB)
- Solidus Bioscience's MetaChip Technology for High- Throughput In Vitro Assessment of Chemical and Drug Candidate Toxicity (7/24/08) (pdf, 24 pp. 1.3 MB)
- U.S. EPA Use of QSAR and Category Approaches in Profiling Hazards of Industrial Chemicals (6/26/08) (pdf, 37 pp. 499 KB)
- Overview of the Contaminant Candidate List 3 (5/22/08) (pdf, 23 pp. 503 KB)
- Screening Chemicals in Commerce to Identify Possible Persistent and Bioaccumulative Chemicals: New Results and Future Work (04/24/08)
  (pdf, 27 pp. 211 KB)
- Chemical Prioritization and Risk Assessment in the 21st Century (03/27/08)
  (pdf, 31 pp., 1.4 MB)
- Collaboration on In Vitro Testing Proposal (02/28/08) (pdf, 37 pp., 6.8 MB)
- BioSeek ToxCast™ Presentation Summary (01/24/08) (pdf, 27 pp., 6.8 MB)
Exposure Science
- Prioritization in REACH (pdf, 32 pp., 166 KB)
- Exposure Science Research at the JRC Institute for Health and Consumer Protection (09/08/09) (pdf, 80 pp., 5.8 MB)
- Exposure Assessment for Chemicals Management (08/10/09) (pdf, 33 pp., 625 KB)
- Holistic Mass Balance Modeling Approach for Screening Chemical Inventories (07/14/09) (pdf, 50 pp., 425 KB)
- Connecting Environment, Biology, and Behavior for Human Exposure and Risk Assessment: Integrative Modeling Approaches (05/05/09) (pdf, 56 pp., 14.1 MB)
- GExFRAME A Web-Based Framework for Accessing Global Consumer Exposure Data, Scenarios, and Models (04/14/09) (pdf, 45 pp., 3.3 MB)
- Gene Expression Profiles: Biomarkers of Inter-Individual Susceptibility to Environmental Agents and Indicators of Exposure (03/10/09) (pdf, 109 pp., 3.9 MB)
- Biomonitoring Equivalents as Screening Tools for Interpretation of Human Biomonitoring Data (02/10/09) (pdf, 36 pp., 646 KB)
- Multimedia MultipathwayModeling of Emissions to Impacts: screening with USEtoxand advanced spatial modeling with IMPACT (01/13/09) (pdf, 36 pp., 3.2 MB)
- Prioritization of HPV Chemicals under the Chemical Assessment and Management Program (ChAMP) (12/08/08) (pdf, 39 pp., 387 KB)
- Assessing the Exposure-Dose-Toxicity Relationship within the EPA's ToxCast Program (11/04/08) (pdf, 36 pp., 2.1 MB)
- Chemical Exposure Priority Setting Tool (CEPST) (10/07/08) (pdf, 32 pp., 220 KB)
- Characterizing Exposure to Indoor VOCs and SVOCs using Simple Mass-Transfer Models (10/07/08) (pdf, 32 pp., 1 MB)
- European Centre for Ecotoxicology and Toxicology of Chemicals Targeted Risk Assessment (ECETOC TRA) Tool (09/09/08) (pdf, 37 pp., 1.24 MB)
- TOXICO-CHEMINFORMATICS: DSSTox and Chemical Structure Annotation for improved data access (08/12/08) (pdf, 62 pp., 3.7 MB)
- Considering Exposure in Priority Setting Categorization of the Domestic Substances List under the Canadian Environmental Protection Act (CEPA) (07/08/08) (pdf, 31 pp., 640 KB)
- Short Term Exposure Prioritization Needs for ToxCast™ (06/17/08 ) (pdf, 37 pp., 6.8 MB)
- Chemical Selection for ToxCast: EPA's Program for Predicting Toxicity and Prioritizing Chemical Testing (05/27/08) (pdf, 13 pp., 1.4 MB)

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