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HHRA Research

Models, Databases, and Tools

Scientists in ORD are translating new research in molecular biology and computational sciences into practical applications for developing hazard and dose-response assessments – a critically important step for advancing risk assessment. This work impacts not only the development of Integrated Risk Information System (IRIS), Integrated Science Assessments (ISAs), and Provisional Peer Reviewed Toxicity Values (PPRTV) assessments, but also helps the Agency to quickly assess and address emerging problems.  ORD scientists create models that are used by risk assessors to develop state-of-the-science risk assessments.  Additionally, ORD develops and maintains tools and databases that inform the development of risk assessments.  EPA also conducts computational toxicology research within ORD, by funding academic centers through the Science to Achieve Results (STAR) grants program, and through collaborations with other Federal partners.  Collectively, this work helps foster efficiency and effectiveness in EPA’s risk assessments.

Additional HHRA Models, Databases, and Tools Links

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