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List of IRIS Substances

For additional assistance or questions about IRIS, contact the IRIS Hotline at (202) 566-1676 (phone), (202) 566-1749 (FAX) or hotline.iris@epa.gov (email).

Tools & Databases

Web Site Description
Benchmark Dose Software EPA software used for benchmark dose modeling analysis. Available as a free download.
Health and Environmental Research Online (HERO) HERO is a database of scientific studies considered and cited in the development of EPA's science assessments, including IRIS Toxicology Reviews and Integrated Science Assessments of criteria air pollutants. HERO is part of the open government initiative to bring transparency to EPA's regulatory process and encourage public participation in the decision-making process.
SCIRUS Exit EPA Disclaimer A science-specific internet search engine.
Chemical Locators and Databases
CAL EPA's Department of Pesticide Regulation (DPR) Chemical/Product Database Queries page Permits a search for: a chemical ingredient by name, CAS number, or DPR chemical code, a chemical ingredient using multiple variables, or registrants by DPR chemical code or CAS Number. You can also search for pesticide products using multiple variables, and view a Report on Registered Active Ingredients.
ChemIDPlus A dictionary of many chemicals, together with their chemical properties and links to other databases and resources.
ChemFinder.com Exit EPA Disclaimer Commercial site for finding chemical structures with links to other databases and resources.
National Institute of Occupational Safety and Health -- NIOSH's databases Numerous NIOSH data resources are available on this Web site.
National Library of Medicine's Medical Subject Headings (MeSH) Browser NLM's controlled vocabulary thesaurus. Can be used to help you identify related terms for describing critical effects, precursor effects, and tumor types.
National Library of Medicine's TOXNET (TOXicology Data NETwork) contains a number of searchable Toxicology databases including the Hazardous Substance Databank (HSDB), Integrated Risk Information System (IRIS), Chemical Carcinogen Research Information System (CCRIS), Toxicology Literature search (TOXLINE), data on mutagenicity studies (GENE-TOX) Developmental and Reproductive Toxicity/Environmental Teratology Information Center (DART/ETIC), Toxics Release Inventory (TRI), and ChemIDPlus.
National Pesticide Information Retrieval System (NPIRS) Exit EPA Disclaimer Database developed by Perdue University and USDA to allow quick retrieval of current information on registered pesticides.
PubMed Provides access to over 11 million citations from MEDLINE and additional life science journals and includes links to many sites providing full text articles and other related resources.
Science Direct Exit EPA Disclaimer Access to scientific journals. Click on "browse A to Z journals" to see a complete list.
US EPA Distributed Structure-Searchable Toxicity (DSSTox) Database Network A project of EPA's Computational Toxicology Program, helping to build a public data foundation for improved structure-activity and predictive toxicology capabilities. The DSSTox website provides a public forum for publishing downloadable, standardized chemical structure files associated with toxicity data.
US EPA EMCI Chemical Reference Index Listing of chemicals monitored by EPA's major program systems: Air (AFS), Water (PCS), Hazardous Waste (RCRIS), Superfund (CERCLIS), and Toxics Release Inventory (TRI), including a complete listing of all chemical references.
US EPA ENVIROFACTS Master Chemical Integrator (EMCI) EMCI allows you to obtain the acronyms, chemical identification numbers, and chemical names reported by the Envirofacts databases (AFS, PCS, RCRAInfo, and TRI).
US EPA OPPTS Resources and Databases Links to a compilation of Office of Prevention, Pesticides and Toxic Substance's pesticide databases and resources.  
US EPA Science Inventory Listing of all EPA's Science and Research including project descriptions and a list of completed products. Powered by the Environmental Information Management System (EIMS).
US EPA Substance Registry System (SRS) EPA's central system for information about regulated and monitored substances; provides a common basis for identification of chemicals and biological organisms listed in EPA regulations and data systems, as well as substances of interest from other sources.
Web of Science Exit EPA Disclaimer Provides access to current and retrospective research journals and contains a unique search tool that allows for forward and backward searching through all available literature.

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