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Recent Additions
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Find notifications (by year) of new IRIS Summary and Toxicological Review postings to IRIS, Federal Register notices, peer review meetings and other announcements about the IRIS Program and Web site. If you like to receive notifications of Recent Addition items, please contact us.
Federal Register Notices about IRIS are also available on the US Government Printing Office (GPO) website.
24 May 2012
Notice: Availabilty of final reports from the peer review meetings of vanadium pentoxide and 1,4-dioxane (inhalation)
On March 7 and then on March 19, 2012 , separate external peer review panel meetings were hosted by an independent contractor for the review of Toxicological Review of Vanadium Pentoxide: In Support of the Summary Information in the Integrated Risk Information System (IRIS) and the Toxicological Review of 1,4-Dioxane (Inhalation): In Support of the Summary Information in the Integrated Risk Information System (IRIS) respectfully. Completing these reviews, a final report of the comments from each of these workshop were collected and are now available.
16 May 2012
EPA announced that the National Academy of Sciences (NAS) will conduct a comprehensive review of the agency’s IRIS program’s assessment development process. This is a follow-up to when in April 2011, NAS recommended several ways to improve the development of IRIS assessments. EPA has embraced these recommendations and is implementing them using a phased approach. Future draft IRIS assessments released for public comment and peer review will demonstrate the progress EPA has made in implementing the NAS recommendations. [ Press Release May 16, 2012]
14 May 2012
[Update] New Schedule for IRIS Acrylonitrile Assessment Announced
EPA has developed a new schedule for completing the IRIS Acrylonitrile assessment, which can be found in IRIS Track (IRISTrack - Acrylonitrile). EPA has decided to make further revisions to the acrylonitrile assessment to more fully address scientific issues in the assessment. The revised draft acrylonitrile assessment will be released for public comment and rigorous, independent expert peer review. EPA will seek to have the peer review performed by the new Chemical Assessment Advisory Committee that is being formed under the auspices of the Science Advisory Board.
7 May 2012
Announcement of 2012 Agenda for IRIS
IRIS announces the IRIS 2012 agenda and is requesting scientific information on health effects that may result from exposure to the chemical substances on this agenda, including assessments that EPA is starting this year. [Federal Register Notice May 7, 2012]
6 April 2012
IRIS posts 2 new Literature Searches for public comment
IRIS announces the availability of literature searches for acetaldehyde (75-07-0) and 1,2,3-trimethlybenzene (526-73-8) and ask the public for any additional scientific information on health effects that may result from exposure to these chemical substances. [Federal Register Notice April 6, 2012]
8 March 2012
Update on Ramazzini Institute data in IRIS assessments EPA announces an update on the use of data from an Italy-based lab, known as the Ramazzini Institute or RI. This decision will impact IRIS assessments under development for methanol, MTBE and ETBE. The draft assessment for acrylonitrile is not affected, as EPA relied on data from sources other than the Ramazzini Institute to complete this draft assessment.
2 March 2012
Notice: IRIS Toxicological Review of Biphenyl (External Peer Review Meeting Announcement)
EPA announces an external peer review meeting for the review of the draft report, IRIS Toxicological Review of Biphenyl (External Review Draft) to be held on April 3, 2012 in Arlington, VA. [Federal Register March 2, 2011]
28 February 2012
[Update] New Schedule for IRIS Hexavalent Chromium Assessment Announced
EPA has developed a new schedule for completing the IRIS hexavalent chromium assessment, which can be found in IRIS Track (IRISTrack - hexavalent chromium). Based on the recommendations of the external peer review panel, which met in May 2011 to review the draft IRIS assessment for hexavalent chromium (oral exposure only), EPA will consider the results of recently and soon to be completed peer-reviewed primary research on the chemical before finalizing the IRIS assessment. The oral assessment will be revised to address the peer review comments and combined with the inhalation assessment, which is currently in draft development. EPA anticipates that the draft assessment for hexavalent chromium (oral and inhalation) will be released for public comment and external peer review in 2013.
21 February 2012
A new Summary for Tetrahydrofuran and a new accompanying Toxicological Review (PDF) (207 pp, 1.22M) have been added to the IRIS website. The Interagency Science Discussion Draft of the Tetrahydrofuran IRIS assessment has also been released.
17 February 2012
A new Summary for 2,3,7,8-Tetrachlorodibenzo-p-dioxin and a new accompanying Support Document have been added to the IRIS Web site. The Interagency Science Discussion Draft of the 2,3,7,8-Tetrachlorodibenzo-p-dioxin IRIS assessment has also been released. [More information on Dioxin can be found on the EPA consumer fact sheet on the Dioxin Science Assessment.]
13 February 2012
Notice: IRIS Toxicological Review of 1,4-Dioxane (External Peer Review Meeting Announcement)
EPA announces an external peer review meeting for the review of the draft report, IRIS Toxicological Review of 1,4-Dioxane (Inhalation) (External Review Draft) to be held on March 19, 2012 in Morrisville, NC. [Federal Register February 13, 2011]
10 February 2012
A new Summary for Tetrachloroethylene (Perchloroethylene) and a new accompanying Toxicological Review (PDF) (1,077 pp, 14.4M) have been added to the IRIS Web site. The Interagency Science Discussion Draft of the Tetrachloroethylene (Perchloroethylene) IRIS assessment has also been released. [More information on PERC can be found on the EPA fact sheet on Tetrachloroethylene/Perchloroethylene]
06 February 2012
Notice: IRIS Toxicological Review of Vanadium Pentoxide (External Peer Review Meeting Announcement)
EPA has announced that an independent public peer review meeting for the draft IRIS Toxicological Review of Vanadium Pentoxide has been scheduled for March 7, 2012 in Arlington, VA. [Federal Register February 6, 2011]
03 January 2012
Notice: SAB Review of IRIS Tox Review of Libby Amphibole Asbestos (External Review Draft)
EPA has announced a public face-to-face meeting of an SAB Panel to review EPA's draft Toxicological Review of Libby Amphibole Asbestos (August 2011). The meeting was held February 6 - 8, 2012 in Alexandria, VA. [Federal Register Notice December 23, 2011].