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Nanotechnology: Toxicity
Highlights
February 12, 2008 - Read the Federal Register notice about EPA's Nanotechnology Research Strategy and meeting to review public comment:
- FR Notice Requesting Public comment on EPA's Nanotechnology Research Strategy and comment review meeting (PDF) (3 pp, 53 K)
- EPA's draft Nanotechnology Research Strategy (PDF) (76 pp, 1.10 MB)
 |
Nanotechnology Search
As nanotechnology progresses from research and development to commercialization and use, it is likely that manufactured nanomaterials and nanoproducts will be released into the environment. EPA is charged with protecting human health and the environment, as well as ensuring that the application of engineered nanotechnology products occur without unreasonable harm to human health or the environment. The unique features of manufactured nanomaterials and a lack of experience with these materials hinder the risk evaluation that is needed to inform decisions about pollution prevention, environmental clean-up and other control measures, including regulation. Beyond the usual concerns for most toxic materials, such as physical and chemical properties, uptake, distribution, absorption, and interactions with organs, the immune system and the environment, the adequacy of current toxicity tests for chemicals needs to be assessed to develop an effective approach for evaluating the toxicity of nanomaterials. To the extent that nanoparticles are redox active or elicit novel biological responses, these concerns need to be accounted for in toxicity testing to provide relevant information needed for risk assessment to inform decision making.
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20 abstract(s) are listed.
| Search Phrase: Nanotechnology Implications: Toxicity |
| # | Identifier | Abstract | Principal Investigator | Annual/ Final Reports | Pubs Count | Institution | Grant Representative | Grant Amount | Project Period | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| << STAR GRANTS AND STAR CENTERS >> | |||||||||||||
| 1 |
R833772 Grant |
Safety/Toxicity Assessment of Ceria (A Model Engineered NP) to the Brain |
Yokel, Robert A. Butterfield, Allan Graham, Ursula M. Grulke, Eric Tseng, Michael T. |
2009
|
Total Pubs:
10 -- No Journals -- -- No Books -- |
University of Kentucky,University of Louisville |
Karn, Barbara |
$2,000,000 |
April 2008 - March 2012 |
||||
| 2 |
R833319 Grant |
Innate Immune Response of an Aquatic Vertebrate Model to Manufactured Nanoparticles Assessed Using Genomic Markers |
Klaper, Rebecca Chen, Jian Goetz, Frederick |
2008
|
Total Pubs:
2 -- No Journals -- -- No Books -- |
University of Wisconsin |
Karn, Barbara |
$398,810 |
April 2008 - March 2010 |
||||
| 3 |
R833325 Grant |
Genomics-based Determination of Nanoparticle Toxicity: Structure-function Analysis |
Bakalinsky, Alan T. Li, Qilin |
Oregon State University,Rice University |
Shapiro, Paul |
$199,993 |
May 2007 - May 2009 |
||||||
| 4 |
R833333 Grant |
Ecotoxicology of Underivatized Fullerenes (C60) in Fish |
Henry, Theodore B. Compton, Robert N. Menn, Fu-Min Sayler, Gary S. |
University of Tennessee - Knoxville |
Krishnan, Bala S. |
$396,807 |
May 2007 - May 2010 |
||||||
| 5 |
R833336 Grant |
Effects of Ingested Nanoparticles on Gene Regulation in the Colon |
Moos, Philip J. Cutler, Ned S. Veranth, John |
2007
|
University of Utah |
Shapiro, Paul |
April 2007 - April 2009 |
||||||
| 6 |
R833316 Grant |
Aquatic Toxicity of Carbon-Based Nanomaterials at Sediment-Water Interfaces |
Deng, Baolin Ingersoll, Chris Li, Hao Wang, Ning |
2007
|
University of Missouri - Columbia,Columbia Environmental Research Center, USGS |
Karn, Barbara |
$399,506 |
April 2007 - March 2010 |
|||||
| 7 |
R833339 Grant |
Nanoparticle Toxicity in Zebrafish |
Mayer, Gregory D. Nadeau, Jay L. Nohe, Anja Smorodin, V. |
University of Maine,McGill University |
Krishnan, Bala S. |
$398,298 |
October 2006 - September 2009 |
||||||
| 8 |
R833320 Grant |
A Rapid In Vivo System for Determining Toxicity of Manufactured Nanomaterials |
Tanguay, Robert L. Harper, Stacey |
2008
|
Total Pubs:
16 Journals: 4 -- No Books -- |
Oregon State University |
Karn, Barbara |
$400,000 |
September 2006 - August 2009 |
||||
| 9 |
R832843 Grant |
Effects of Nanomaterials on Human Blood Coagulation |
Perrotta, Peter L. Gouma, Pelagia-Irene |
2006
|
Total Pubs:
11 Journals: 2 -- No Books -- |
West Virginia University,SUNY at Stony Brook |
Shapiro, Paul |
$375,000 |
February 2006 - January 2009 |
||||
| 10 |
R832534 Grant |
Microbial Impacts of Engineered Nanoparticles |
Alvarez, Pedro J. Wiesner, Mark R. |
2006
|
Total Pubs:
16 Journals: 12 Books: 3 |
Rice University,Duke University |
Karn, Barbara Lasat, Mitch |
$375,000 |
December 2005 - December 2008 |
||||
| 11 |
R832536 Grant |
Structure-function Relationships in Engineered Nanomaterial Toxicity |
Colvin, Vicki L. |
2007
|
Total Pubs:
15 Journals: 6 -- No Books -- |
Rice University |
Karn, Barbara |
$375,000 |
December 2005 - November 2008 |
||||
| 12 |
R832527 Grant |
Chemical Fate, Biopersistance, and Toxicology of Inhaled Carbonaceous Nanoscale Materials |
McDonald, Jacob D. Dix, Kelly J. Gigliotti, Andrew Seagrave, Jean Clare VanderWal, Randall L. |
Final
|
Total Pubs:
2 Journals: 1 -- No Books -- |
Lovelace Respiratory Research Institute,NASA-Glenn |
Karn, Barbara |
$350,000 |
December 2005 - November 2008 |
||||
| 13 |
R832525 Grant |
Cellular Uptake and Toxicity of Dendritic Nanomaterials: An Integrated Physicochemical and Toxicogenomics Study |
Diallo, Mamadou S. Goddard, William A. Riechmann, Jose Luis |
2006
|
California Institute of Technology,Howard University |
Savage, Nora |
$375,000 |
November 2005 - November 2008 |
|||||
| 14 |
R832842 Grant |
Acute and Developmental Toxicity of Metal Oxide Nanoparticles in Fish and Frogs |
Theodorakis, Christopher Carraway, Elizabeth Cobb, George |
2006
|
Southern Illinois University - Edwardsville,Clemson University,Texas Tech University |
Krishnan, Bala S. |
$375,000 |
October 2005 - October 2008 |
|||||
| 15 |
R832528 Grant |
Role of Particle Agglomeration in Nanoparticle Toxicity |
Gordon, Terry Chen, Lung Chi Cohen, Beverly S. |
2006
|
Total Pubs:
4 -- No Journals -- -- No Books -- |
New York University: Nelson Institute of Environmental Medicine -Tuxedo |
Karn, Barbara |
$375,000 |
October 2005 - September 2008 |
||||
| 16 |
R832635 Grant |
Assessment of the Environmental Impacts of Nanotechnology on Organisms and Ecosystems |
Bonzongo, Jean-Claude J. Bitton, Gabriel Kopelevich, Dmity |
2006
|
Total Pubs:
2 Journals: 1 -- No Books -- |
University of Florida |
Lasat, Mitch |
$375,000 |
October 2005 - September 2008 |
||||
| 17 |
R831717 Grant |
Impacts of Manufactured Nanomaterials on Human Health and the Environment - A Focus on Nanoparticulate Aerosol and Atmospherically Processed Nanoparticulate Aerosol |
Grassian, Vicki H. O'Shaughnessy, Patrick Thorne, Peter S. |
2005
|
Total Pubs:
17 Journals: 2 -- No Books -- |
University of Iowa |
Krishnan, Bala S. |
$335,000 |
October 2004 - September 2007 |
||||
| 18 |
R831715 Grant |
Evaluating Nanoparticle Interactions with Skin |
Monteiro-Riviere, Nancy A. Riviere, Jim E. |
2005
|
Total Pubs:
119 Journals: 16 Books: 5 |
North Carolina State University |
Savage, Nora |
$328,972 |
September 2004 - September 2007 |
||||
| 19 |
R831719 Grant |
Physical and Chemical Determinants of Nanofiber/Nanotube Toxicity |
Hurt, Robert H. Kane, Agnes B. |
2005
|
Total Pubs:
22 Journals: 5 -- No Books -- |
Brown University |
Savage, Nora |
$335,000 |
August 2004 - July 2007 |
||||
| 20 |
R831714 Grant |
Health Effects of Inhaled Nanomaterials |
Pinkerton, Kent E. Guo, Ting |
2005
|
Total Pubs:
3 Journals: 1 -- No Books -- |
University of California - Davis |
Savage, Nora |
$334,998 |
July 2004 - June 2007 |
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| About Your Results | |
| Total Number of Abstracts: | 20 |
| Total Number of Abstracts, excluding Center sub-projects: | 20 |
| Total Number of Progress Reports: | 25 |
| Total Number of Final Reports: | 4 |
| Total Number of Publications: | 239 |
| Total Number of Journal Articles: | 50 |