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Meeting the Challenges of Particulate Matter Air Pollution: EPA’s PM Research Centers

Tuesday, September 28, 2004 · Hotel Washington · 515 15th Street, NW, Washington DC

PM Centers and EPA present and discuss recent research results

9:00 Welcome
9:05 - 11:05 Theme: Particle toxicity and mechanisms
What characteristics of particles produce toxicity – size, composition, interactive effects, nature of the matrix, primary v. secondary? What is the relationship between mode of formation and toxicity? Can we reach some preliminary conclusions about mechanisms?

Centers each provide 20 minute presentations addressing some aspects of these questions. Each followed by 10 minute discussion.

9:05 - 9:25 “Three Tiers of Oxidative Stress in Response to Particulate Air Pollution”
Andre Nel, Southern California Particle Center And Supersite - Presentation (PDF, 43 pp., 1.32 MB, about PDF)
9:35 - 9:55 "Particle toxicity and pollutant gas/particle interactions in a rat model
of myocardial infarction"

John Godleski, Harvard University - Presentation (PDF, 18 pp., 645 KB, about PDF)

10:05-10:25 "In search of mechanisms for ultrafine/fine PM induced cardiovascular

Günter Oberdörster, University of Rochester - Presentation (PDF, 25 pp., 2.78 MB, about PDF)
10:35-10:45 General Discussion of Above Theme
10:45-11:00 Break
New Research From Other Centers
11:00-11:20 “Detroit Exposure Aerosol Research Study”
Linda Sheldon, U.S. EPA - Presentation (PDF, 20 pp., 262 KB, about PDF)
11:30-11:50 “Exhaled Nitric Oxide in Children with Asthma”
Jane Koenig, University of Washington - Presentation (PDF, 15 pp., 146 KB, about PDF)
12:00-12:20 “Subchronic CAPs Exposures in Mice: Biological Endpoints and Exposure Assessment”
Lung Chi Chen, New York University - Presentation (PDF, 32 pp., 2.15 MB, about PDF)

12:30-12:50 Wrap-up and closing remarks – EPA


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