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Extramural Research

2008 Level II Scientific and Technological Achievement Awards (STAA) Awarded Nominations

Grantee Research Project Results

Extramural Research Search

Level II awards - are for those who have accomplished a notably excellent research or technological effort that has qualities and values similar to, but to a lesser degree, than those described under Level I. Awarded research has timely consequences and contributes as an important scientific/technological achievement within its discipline or field of study.

Children  Aquatic study  Shoreline  Scientist at work

Nominations Recommended for a Level II Award ($5,000) -- Total of Eighteen
Nom. # Titles and Citations of Submitted Paper Eligible Authors* and Nominating Organization Ineligible Authors and Organization Citation
S08ER0013 (1) Progress towards development of an amphibian-based thyroid screening assay using "Xenopus laevis": Organismal and thyroidal responses to the model compounds 6-propylthiouracil, methimazole, and thyroxine
Toxicological Sciences, 87:353-364 (2005)
(2) Metamorphic inhibition of "Xenopus laevis" by sodium perchlorate: Effects on development and thyroid histology
Environmental Toxicology and Chemistry, 24:926-933 (2005)
Sigmund Degitz
Joseph Tietge
Gary Holcombe
Patricia Kosian
Kevin Flynn
Joseph Korte
Douglas Wolf
Leroy Anderson

NHEERL, Duluth, MN
Development of an Amphibian-Based Thyroid Screening Assay
S08ER0016 Evaluating effects of low quality habitats on regional population growth in "Peromyscus leucopus": Insights from field-parameterized spatial matrix models
Landscape Ecology, 22:45-60 (2007)
Jason Grear

NHEERL, Narragansett, RI
Catherine E. Burns - University of Maine Research into Methods of Assessing Localized Stressor Effects on Larger Scale Persistence of Wildlife Populations
S08ER0022 (1) Sources of bias in weighted average inferences of environmental conditions
Journal of Paleolimnology, 34:245-255 (2005)
(2) Using biological assemblage composition to infer the values of covarying environmental factors
Freshwater Biology, 52:1159-1175 (2007)
(3) Effects of measurement error inferences of environmental conditions
Journal of the North American Benthological Society, 26(1):152-163 (2007)
Lester L. Yuan

NCEA, Washington, DC
Developing New Analytical Methods That Identify the Causes of Impairment in Streams from Biological Assemblage Characteristics
S08HE0029 Identification of Estrogenic Compounds Emitted from the Combustion of Computer Printed Circuit Boards in Electronic Waste
Environmental Science and Technology, 41(24):8506-8511 (2007)
Vickie S. Wilson
Clyde V. Owens
Christy Lambright
Kathy Bobseine
Brian K. Gullett
L. Earl Gray, Jr.

NRMRL, Research Triangle Park, NC
Bryce Ryan Exceptional Research Demonstrating the Importance of Investigating Estrogens from Computer Printed Circuit Boards
S08HE0032 Transcriptional responses in thyroid tissues from rats treated with a tumorigenic and a non-tumorigenic triazole conazole fungicide
Toxicology and Applied Pharmacology, 233: (2007)
Susan D. Hester
Stephen C. Nesnow

NHEERL, Research Triangle Park, NC
An Exceptional Contribution That Applied Novel Bioinformatic Tools to Identify a Mode of Action for a Thyroid Tumorigenic Conazole Fungicide
S08HE0041 Chronic Arsenic Exposure and Cardiac Repolarization Abnormalities with QT Interval Prolongation in a Population-based Study
Environmental Health Perspectives (EHP), 115(5):690-694 (2007)
Judy Mumford

NHEERL, Research Triangle Park, NC
William E. Sanders - University of North Carolina, Chapel Hill
Kegong Wu - Inner Mongolia Center for Endemic Disease Control and Research
Richard Kwok - RTI International
Yajuan Xia - Inner Mongolia Center for Endemic Disease Conrtol and Research
Zhihui Yang - Ba Men Anti-Epidemic Station
James Foster - Wake Heart Associates
Linking Chronic Arsenic Exposure and Cardiac Effects on Electrical Signals in Humans
S08HE0045 Identification of interspecies concordance of mechanisms of arsenic-induced bladder cancer
Toxicology In Vitro, 21(8):1513-1529 (2007)
Banalata Sen
Susan D. Hester
Douglas C. Wolf

NHEERL, Research Triangle Park, NC
Banalata Sen
Yaron Turpaz - Affymetrix
Andrej Bugrim - GeneGo, Inc.
Jacques Retief - Illumina
In Vitro-In Vivo and Interspecies Concordance of Mechanisms of Arsenic-Induced Bladder Cancer
S08HE0132 (1) Quantitative comparisons of the acute neurotoxicity of toluene in rats and humans
Toxicological Sciences, 100:146-155 (2007)
(2) A dosimetric analysis of the acute behavioral effects of inhaled toluene in rats
Toxicological Sciences, 99:181-189 (2007)
(3) Acute toluene exposure alters rat visual function in proportion to momentary brain concentration
Toxicological Sciences, 99:572-581 (2007)
Philip J. Bushnell
Vernon A. Benignus
William K. Boyes
Wendy M. Oshiro
Elaina M. Kenyon
Timothy J. Shafer
Tracey E. Samsam
Q. Todd Krantz
Mark Bercegeay
Ambuja Bale

NHEERL, Research Triangle Park, NC
Research Quantifying Animal-to-Human Extrapolation in Risk Assessment, Using Toluene as a Case Study
S08MM0060 A General Indication of the Contemporary Background Levels of PCDDs, PCDFs, and Coplanar PCBs in the Ambient Air over Rural and Remote Areas of the United States
Environmental Science and Technology, 41(5):1537-1544 (2007)
David H. Cleverly
Joseph Ferrario
Christian Byrne

NCEA, Washington, DC
Karen Riggs - Battelle Memorial Institute
Darrell Joseph - Battelle Memorial Institute
Pamela Hartford - Battelle Memorial Institute
The High-Quality Scientific Achievement of Successfully Measuring Dioxins and PCBs in Rural and Remote Areas of the U.S.
S08MM0062 (1) Metabolomic evaluation of rat liver and testis to characterize the toxicity of triazole fungicides
Metabolomics, 2(2):63-73 (2006)
(2) Raman spectroscopy-based metabolomics for differentiating exposures to triazole fungicides using rat urine
Analytical Chemistry, 79(19):7324-7332 (2007)
(3) NMR analysis of male fathead minnow urinary metabolites: A potential approach for studying impacts of chemical exposures
Aquatic Toxicology, 85(2):104-112 (2007)
Drew R. Ekman
Timothy W. Collette
Quincy Teng
David J. Dix
Gerald T. Ankley
Dan L. Villeneuve
Kathleen M. Jensen
John C. Rockett

NERL, Research Triangle Park, NC
Daniel P. Cherney - ExxonMobil Chemical Company
Hector C. Keun - Imperial College of Scinece, Technology and Medicine
Dalma Martinovic
Charles D. Eads - The Proctor and Gamble Company
Carrie M. Furnish - The Proctor and Gamble Company
Rachel N. Murrell - North Carolina State University
Establishing an Internationally Recognized Program in Environmental Metabolomics to Assess Chemical Exposure Risk
S08MM0067 (1) Mercury concentration in fish from streams and rivers throughout the western United States
Environmental Science & Technology, 41(1):58-65 (2007)
(2) Mercury concentration in frozen whole-fish homogenates is insensitive to holding time
Arch Environ Contam Toxicol, 53:411-417 (2007)
Spencer A. Peterson
John Van Sickle
David V. Peck

NHEERL, Corvallis, OR
Alan T. Herlihy - Oregon State University
Robert M. Hughes - Oregon State University
Improvement of Methods to Assess Regional Fish Tissue Mercury Contamination
S08MM0068 (1) Competitive Metagenomic DNA Hybridization Identifies Host-Specific Microbial Genetic Markers in Cow Fecal Samples
Applied and Environmental Microbiology, 72(6):4054-4060 (2006)
(2) Identification of Bacterial DNA Markers for the Detection of Human Fecal Pollution in Water
Applied and Environmental Microbiology, 73(8):2416-2422 (2007)
Orin C. Shanks
Jorge W. Santo Domingo
Catherine A. Kelty

NRMRL, Cincinnati, OH
James E. Graham - University of Louisville School of Medicine
Jingrang Lu
Regina Lamendella
Scientific and Technical Achievement in the Field of Water Quality Monitoring and Indicators of Fecal Pollution
S08OR0080 (1) Characterizing residue transfer efficiencies using a fluorescent imaging technique
Journal of Exposure Analysis and Environmental Epidemiology now the Journal of Exposure Science and Environmental Epidem, 15(3):261-270 (2005)
(2) Measuring potential dermal transfer of a pesticide to children in a daycare center
Environmental Health Perspectives, 114(2):264-269 (2006)
(3) Comparing surface residue transfer efficiencies to hands using polar and non-polar fluorescent tracers
Environmental Science & Technology, : (2007)
Elaine A. Cohen Hubal
Peter P. Egeghy
Jack C. Suggs
Kelly W. Leovic

NCCT, Research Triangle Park, NC
Marcia G. Nishioka - Battelle Memorial Institute
Gerald G. Akland
William A. Ivancic - Battelle Memorial Institute
M. Morara - Battelle Memorial Institute
Research That Improves Our Understanding of Children's Exposure to Pesticides in the Residential Environment
S08RA0087 The importance of the Montreal Protocol in protecting climate
Proceedings of the National Academy of Sciences, 104(12):4814-4819 (2007)
Stephen O. Andersen

OAR, Washington, DC
Guus J.M. Velders - Netherlands Environmental Assessment Agency
John S. Daniel - National Oceanic and Atmospheric Administration
David W. Fahey - National Oceanic and Atmospheric Administration
Mack McFarland - DuPont Fluoroproducts
Synthesis and Communication of Stratospheric Ozone and Climate Science
Linked with S08RA0100
Drowning in disinfection byproducts? Assessing swimming pool water
Environmental Science & Technology, 41(2):363-372 (2007)
Susan D. Richardson
David M. DeMarini

NERL, Research Triangle Park, NC
Christian Zwiener - Engler-Bunte-Institute
Tamara Grummt - Federal Environmental Agency
Thomas Glauner - Engler-Bunte-Institute
Fritz H. Frimmel - Engler-Bunte-Institute
Summarizing the Water Chemistry and Health Effects Associated with Disinfection By-Product Exposure Via Swimming
S08RA0097 The Effectiveness of Voluntary Environmental Programs--A Policy at a Crossroads?
Policy Studies Journal, 35(4):689-722 (2007)
Dinah Koehler

NCER, Washington, DC
Greatly Increasing the Agency's Understanding of the Effectiveness of Voluntary Environmental Programs
Linked with S08RA0092
Occurrence, genotoxicity, and carcinogenicity of regulated and emerging disinfection by-products in drinking water: A review and roadmap for research
Mutation Research--Reviews, 636(1-3):178-242 (2007)
Susan D. Richardson
David M. DeMarini
Rita Schoeny

NERL, Research Triangle Park, NC
Elizabeth D. Wagner - University of Illinois at Urbana-Champaign
Michael J. Plewa - University of Illinois at Urbana-Champaign
Creating a Roadmap for Research on Regulated, and Emerging, Unregulated, Disinfection By-Products in Drinking Water
Key to Acronyms used in the above Table
OA Office of the Administrator
NERL National Exposure Research Laboratory
NHEERL National Health and Environmental Effects Laboratory
NRMRL National Risk Management Research Laboratory
OAQPS Office of Air Quality Planning and Standards
OPP Office of Pesticide Programs
ORIA Office of Radiation and Indoor Air
ORCR Office of Resource Conservation and Recovery
OSCP Office of Science Coordination and Policy
*Note: The percentages given after name represent the current percent of the total level of effort as documented in the EPA nomination.

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