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David L. Lattier

I am involved with research that spans an array of molecular and cellular disciplines, and methods development within those scientific areas that will lead to immediate and transferable bioindicators central to a program in exposure science. I currently serve as a delegate to the USEPA Genomics Task Force, which was responsible for promulgating the Interim Policy on Genomics and publishing a work on the implications, and potential applications, of genomics research at the USEPA, including research needs in the area of toxicogenomics and risk assessment. Additionally, currently Co-Chair of the Genomics Framework Performance Based Quality Assurance Workgroup, a group appointed by USEPA Science Policy Council. The joint genomics framework workgroups (six total) have composed interim guidance for microarray based approaches that outlines the Agency’s acceptance criteria for genomics data in support of regulatory claims.

Following three years in development, an epigenetic approach to monitoring Mode of Action (MOA)-specific biotic exposures in aquatic systems, developed in EERD by DL Lattier, is currently undergoing laboratory validation. This method, which precedes any such investigative undertaking within USEPA ORD, is predicated on epigenomics, and aims to characterize discernible, MOA-specific regions, differentially revealed in exposed methylomes of eukaryotic organisms. Our application of this protocol will target freshwater aquatic organisms across subphyla, Vertebrata and Urochordata.

Biographical Information

Name: David L. Lattier
Title:Research Molecular Biologist

Contact Info:

Ecological Exposure Research Division
National Exposure Research Laboratory
Environmental Protection Agency
26 W. Martin Luther King Jr. Dr. (MD579)
Cincinnati, OH 45268

Phone: 513-569-7976
Email: lattier.david@epa.gov

Education

  • Ph.D. in Developmental Molecular Biology, 1989, University of Cincinnati, College of Medicine and Cincinnati Children’s Hospital, Institute for Developmental Research
  • B.S., Biology and Mathematics, 1984, University of Cincinnati

Professional Experience

  • Senior Scientist and Research Molecular Biologist, USEPA, ORD/NERL, 2007 to Present
  • Research Molecular Biologist, USEPA, ORD/NERL, 1997 to 2007
  • Fellow, Oak Ridge Institute for Science and Education, USEPA, ORD/NERL, 1994 to 1997
  • New Investigator, National Institutes of Health (NIH), National Institute of Heart, Lung and Blood Program, University of Cincinnati, College of Medicine and Cincinnati Children’s Hospital, 1989 to 1993

Selected Honors and Awards

  • USEPA/ORD Teamwork Award; Small Fish Computational Toxicology Team, 2010
  • USEPA, Office of Water, Science and Technology Achievement Award, 2009
  • USEPA, Promotion to Senior Scientist, Technical Qualification Board, 2007
  • USEPA/ORD, Honor Award, 2007
  • USEPA, Science and Technology Achievement Award, Honorable Mention, 2006
  • USEPA/ORD, Bronze Medal, Efforts in Technology Transfer, 2003
  • USEPA, Science and Technology Achievement Award, Level II, 1998
  • Appointment with confirmation by the National Institutes of Health (NIH), to Cincinnati Children's Hospital Medical Center, Institutional Biosafety and Review Committee.

Publications and Presentations

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