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Statistical Analysis for Biological Methods
The Ecological Exposure Research Division (EERD) is providing four U.S. EPA statistical computer programs which are to be used to perform Dunnett's Procedure, Probit Analysis, the Trimmed Spearman-Karber Method and the Linear Interpolation (ICp) Method. The programs have been reviewed and tested on a series of aquatic toxicity data sets by scientists and statisticians in the EERD.
These programs should provide satisfactory analysis of most data sets. However, if upon usage of these programs, you suspect that the results are not in line with expectations or with results obtained using other software, our Division would appreciate knowing about your concerns. If you have any questions regarding these programs, please contact Jim Lazorchak or Don Klemm.
Dunnett's Procedure
Please read the User's Guide before running the program. The program and the user's guide are compressed. The User's Guide is formatted in ASCII, WP5.1.
Probit Analysis
Please read the User's Guide before running the program. The program and the user's guide are compressed. The User's Guide is formatted in ASCII, WP5.1.
Trimmed Spearman-Karber Method
Please read the User's Guide before running the program. The program and the user's guide are compressed. The User's Guide is formatted in ASCII, WP5.1.
If, while using the Trimmed Spearman-Karber program, the automatic trim is 0%, the resulting LC50 will be the same as if the Spearman-Karber method had been used.
Linear Interpolation (ICp) Method
Please read the User's Guide before running the program. The program and the user's guide are compressed. The User's Guide is formatted in WP5.1. If the format is inadequate please contact Teresa Norberg-King at the Environmental Research Laboratory - Duluth MN at (218) 720-5520 to request a hard copy of the ICP program's user's guide.