DSSTox

Distributed Structure-Searchable Toxicity (DSSTox) Database Network is a project of EPA's National Center for Computational Toxicology, helping to build a public data foundation for improved structure-activity and predictive toxicology capabilities. The DSSTox website provides a public forum for publishing downloadable, structure-searchable, standardized chemical structure files associated with toxicity data. More>

v 2.0

DSSTox Structure-Browser information Page

11 August 2009

NTPBSI: National Toxicology Program Bioassay On-line Database Structure-Index Locator File ** Updated to v4c
Corresponds to updated content of NTP website as of 28 July 2009.

27 March 2009

ARYEXP: European Bioinformatics Institute (EBI) ArrayExpress Repository for Gene Expression Experiments **Updated to v2a
Corresponds to updated content of EBI ArrayExpress website as of 20 January 2009.

GEOGSE: National Center for Biotechnology Information (NCBI) Gene Expression Omnibus (GEO) Series Experiments **Updated to v2a
Corresponds to updated content of NCBI GEO website as of 02 February 2009.

NTPHTS: National Toxicology Program High-Throughput Screening Structure-Index File **Updated to v2c
Minor modifications to 9 structures based on additional review.

19 February 2009

KIERBL: EPA Estrogen Receptor Ki Binding Study (Laws et al.) Database File ** New File
Includes experimental Estrogen Receptor (ER) binding IC50 and Ki results for 50 chemicals (17 binders) included in the Main Citation (Laws et al., 2006) and previously unpublished results for 228 structurally diverse environmental chemicals for which no ER binding was observed in initial screening studies.

ARYEXP: European Bioinformatics Institute (EBI) ArrayExpress Repository for Gene Expression Experiments **Updated to v2a
Corresponds to updated content of EBI ArrayExpress website as of 20 January 2009.

GEOGSE: National Center for Biotechnology Information (NCBI) Gene Expression Omnibus (GEO) Series Experiments **Updated to v2a
Corresponds to updated content of NCBI GEO website as of 02 February 2009.