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Simulating Metabolism of Xenobiotic Chemicals as a Predictor of Toxicity

Peer Reviewed Publications:

Mazur, C. S.; Kenneke, J. F. 2008. Cross-species comparison of conazole fungicide metabolites using rat and rainbow  trout (Onchorhynchus mykiss) hepatic microsomes and purified human CYP 3A4. Environmental Science and Technology, 42:947-954.

Mazur, C. S.; Kenneke, J.F.; Tebes-Stevens, C. Okino, M. S.; Lipscomb, J. C. 2007.  In vitro metabolism of the fungicide and environmental contaminant trans-bromuconazole and implications for risk assessment.  Journal of Toxicology and Environmental Health, Part A, 70:1241-1250.

Kenneke, J. F. 2006.  Environmental fate and ecological risk assessment for the reregistration of antimycin A (PC Code 006314), Appendix D: In vitro mammalian metabolism and Appendix G: Summary of antimycin hydrolysis research, U.S. EPA, Office of Pesticide Programs, Reregistration Eligibility Decision (RED) on Antimycin A

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