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Bacillus subtilis Strain QST 713 (006479) Fact Sheet

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Issued: 6/00

  1. Description of the Active Ingredient
  2. Use Sites, Target Pests, and Application Methods
  3. Assessing Risks to Human Health
  4. Assessing Risks to the Environment
  5. Regulatory Information
  6. Producer Information
  7. Additional Contact Information

Summary

Bacillus subtilisstrain QST 713 is a naturally occurring widespread bacterium that can be used to control plant diseases and fungal pathogens including: blight, scab, gray mold, and several types of mildew. Based on available information, the bacterium appears to have no adverse effects on humans or the environment. However, additional data are needed to ensure that products containing this bacterium are safe for honey bees, wasps, fish, and aquatic invertebrates.


  1. Description of the Active Ingredient
  2. Bacillus subtilis strain QST 713 is a widespread bacterium found in soil, water, and air. Bacillus subtilis strain QST 713 controls the growth of certain harmful bacteria and fungi, presumably by competing for nutrients, growth sites on plants, and by directly colonizing and attaching to fungal pathogens.

  3. Use Sites, Target Pests, and Application Methods
  4. Top of Page

  5. Assessing Risks to Human Health
  6. No harmful health effects to humans are expected from use of B. subtilis strain QST 713. Appropriate tests found no evidence that the bacterium is infectious or significantly toxic to humans. However, contact with B. subtilis strain QST 713 products may cause redness or irritation to the skin. To minimize the risk of adverse reactions in applicators and handlers, EPA is requiring these workers to use appropriate personal protective equipment.

  7. Assessing Risks to the Environment
  8. Available studies show that no adverse effects are expected to non-target organisms, with the possible exception of honey bees, when products containing B. subtilis strain QST 713 are used in accordance with label instructions. However, because of some difficulties associated with interpreting the results of these studies, EPA is requiring additional tests to confirm that use of pesticide products with B. subtilis strain QST 713 will not infect or otherwise harm honey bees, wasps, shrimp and other aquatic invertebrates. Meanwhile, to minimize the risk to honey bees, applicators are not allowed to spray areas where bees are actively foraging. After the results of the additional studies become available, EPA will decide whether this use restriction can be lifted.

  9. Regulatory Information
  10. B. subtilis strain QST 713 was registered (licensed for sale) in June 2000 for a two-year period ending July 1, 2002. At that time, EPA will evaluate the new data that the registrant has submitted, and decide whether to issue a registration without an expiration date.

  11. Producer Information
  12. AgraQuest, Inc.,
    1530 Drew Ave.,
    Davis, CA 95616

  13. Additional Contact Information
Ombudsman, Biopesticides and Pollution Prevention Division (7511P)
Office of Pesticide Programs
Environmental Protection Agency
1200 Pennsylvania Avenue, NW
Washington, D.C. 20460

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