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Thymol (5-methyl-2-isopropyl-1-phenol) (080402) Fact Sheet

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  1. Description of the Active Ingredient
  2. Use Sites, Target Pests, and Application Methods
  3. Assessing Risks to Human Health
  4. Assessing Risks to the Environment
  5. Regulatory Information
  6. Registrant Information
  7. Additional Contact Information

  1. Description of the Active Ingredient
  2. Active Ingredient Name: Thymol

    OPP Chemical Code: 080402 (CAS #: 89-83-8)

    Thymol is a constituent of oil of thyme, a naturally occurring mixture of compounds in the plant Thymus vulgaris (thyme).

  3. Use Sites, Target Pests, and Application Methods
  4. Assessing Risks to Human Health
  5. Mammalian laboratory studies show that thymol, at high concentrations, is corrosive to skin and eye, it is also a skin sensitizer. In any case, the public will not be exposed to thymol in the registered end use product. This is due to the fact that the end-use product is applied within bee hives. Every end-use product will be assessed for potential human exposure and toxicity. Workers are required to wear appropriate personal protective equipment to minimize their exposure.

  6. Assessing Risks to the Environment
  7. Thymol is toxic to aquatic invertebrates. Because thymol will be used on land (inside beehives) exposure to aquatic organisms is not expected. The label of the registered end-use product instructs users not to dispose of the product in bodies of water. For each potential end product, EPA will determine if additional non-target studies are needed.

  8. Regulatory Information
  9. Year the active ingredient was first registered: 1964

    Number of registered products as of March 2006: 1

    Product name: Apiguard

  10. Registrant Information
  11. VITA (Europe) Limited
    c/o Landis International

    P.O. Box 5126
    Valdosta, GA 31603
    Contact: Ronald Landis

  12. Additional Contact Information
  13. Ombudsman, Biopesticides and Pollution Prevention Division (7511P)
    Office of Pesticide Programs
    Environmental Protection Agency
    1200 Pennsylvania Avenue, NW
    Washington, D.C. 20460

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