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Lepidopteran Pheromones Fact Sheet

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Issued: 09/01

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  1. Description of the Active Ingredient
  2. Use Sites, Target Pests, And Application Methods
  3. Assessing Risks to Human Health
  4. Assessing Risks to the Environment
  5. Regulatory Information
  6. Additional Contact Information
  7. Female moth mating pheromones approved as pesticides

Summary

Lepidopteran pheromones are used to disrupt the mating behavior of certain moths whose larvae destroy crops and trees. Data indicate that these compounds do not present any known risks to humans or the environment.

  1. Description of the Active Ingredient
  2. Pheromones are volatile chemicals produced by a given species to communicate with other individuals of the same species to change their behavior. For example, various species use pheromones to attract a mate, to mark territory, or to warn others of danger. Pheromones are usually effective in tiny amounts.

    The lepidopteran group of insects includes butterflies and moths. All of the lepidopteran pheromones that EPA has approved for pesticide use are chemicals produced by female moths to attract a mate. The pesticide products contain synthetic versions of these naturally occurring compounds. Sometimes the relative amounts of several pheromone chemicals in a pesticide product determine which specific pests are controlled.

    When the pesticide product releases pheromone into the air where males are looking for females, the males become confused and cannot easily locate the females. As a result, many of the females do not mate and lay eggs, and there are many fewer offspring than usual.

    A list of the currently approved lepidopteran pheromones is attached

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  3. Use Sites, Target Pests, And Application Methods
  4. Assessing Risks to Human Health
  5. Based on low toxicity in animal testing, and expected low exposure to humans, no risk to human health is expected from the use of these pheromones. During more than 10 years of use of lepidopteran pheromones as pesticides, no adverse effects have been reported.

    The safety record for lepidopteran pheromones has allowed the Agency to conclude that consumption of food containing residues of the pheromones presents no risk. In addition, these pheromones can be used experimentally without a permit on up to 250 acres, versus the 10-acre limit imposed on other pesticides.

  6. Assessing Risks to the Environment
  7. Adverse effects on non target organisms (mammals, birds, and aquatic organisms) are not expected because these pheromones are released in very small amounts to the environment and act on a select group of insects.

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  8. Regulatory Information
  9. As of November 1999, EPA had registered (licensed for sale) approximately 20 moth mating pheromones as pesticide active ingredients and more than 60 individual pesticide products containing these active ingredients. See below for examples).

  10. Additional Contact Information:
  11. Ombudsman, Biopesticides and Pollution Prevention Division (7511P)
    Office of Pesticide Programs
    Environmental Protection Agency
    1200 Pennsylvania Avenue, NW
    Washington, D.C. 20460

     

     

     

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    Female moth mating pheromones approved as pesticides

    Pests Controlled Use Sites Chemical Name of Pheromone
    (OPP Chemical Code)
    Note: When 2 or more pheromones are listed in a cell, various mixtures of the pheromones have been approved for use against the pest)
    CAS Number
    Artichoke plume moth
    Artichokes
    53939-28-9
    Beet armyworm
    Alfalfa
    Cotton
    Strawberries
    Vegetables (various)
    Tobacco
    (Z,E) -9,12-Tetradecadienyl acetate (117203) BRAD (20 pages, 222 K, about PDF) (Z)-9-Tetradecen-1-ol (119409)
    31654-77-0
    35153-15-2
    Blackheaded fire worm
    Cranberries
    Fruit
    (Z)-11-Tetradecenyl acetate (128980)
    20711-10-8
    Codling moth
    Fruit
    Nuts
    Lauryl alcohol (001509)
    Myristyl alcohol (001510)
    (E,E) -8,10-Dodecadien-1-ol (129028)
    (Z) -11-Tetradecenyl acetate (128980)
    112-53-8
    112-72-1
    33956-49-9
    20711-10-8
    Codling moth
    Fruit
    Nuts
    Ornamental trees / shrubs
    Uncultivated agricultural areas
    (E,E) -8,10-Dodecadien-1-ol (129028)
    33956-49-9
    Diamondback moth
    Manufacturing use
    (Z)-11-Hexadecenyl Acetate (129071)
    34010-21-4
    Douglas fir tussock moth
    Douglas fir trees
    (Z)-6-Heneicosen-11-one (129060)
    54884-65-4
    Eastern Pine Shoot Borer
    Forest trees
    Woodland trees
    35148-19-7
    Grapeberry moth
    Grapes
    Vine fruit
    (Z)-9-Dodecenyl acetate (129004)
    16974-11-1
    Grapeberry moth
    Grapes
    (Z)-11-Tetradecenyl acetate (128980)
    (Z)-9-Dodecenyl acetate (129004)
    20711-10-8
    16974-11-1
    Gypsy moth
    Forest trees
    Ornamental evergreen trees and shrubs
    cis-7,8-Epoxy-2-methyloctadecane (114301)
    29804-22-6
    Hickory shuckworm
    Fruits
    Nuts
    Uncultivated agricultural areas
    (E,E) -8,10-Dodecadien-1-ol (129028)
    33956-49-9
    Hickory shuckworm
    Fruit
    Nuts
    Lauryl alcohol (001509)
    Myristyl alcohol (001510)
    (E,E) -8,10-Dodecadien-1-ol (129028)
    (Z) -11-Tetradecenyl acetate (128980)
    112-53-8
    112-72-1
    33956-49-9
    20711-10-8
    Koa seed worm
    Fruit
    Nuts
    (Z)-8-Dodecen-1-yl acetate (128906)
    (E)-8-Dodecen-1-yl-acetate (128907)
    (Z)-8-Dodecen-1-ol (128908)
    28079-04-1
    38363-29-0
    40642-40-8
    Leafrollers (various)
    Cranberries
    Fruit
    (Z)-11-Tetradecenyl acetate (128980)
    20711-10-8
    Macadamia nut borer
    Fruit
    Nuts
    (Z)-8-Dodecen-1-yl acetate (128906)
    (E)-8-Dodecen-1-yl-acetate (128907)
    (Z)-8-Dodecen-1-ol (128908)
    28079-04-1
    38363-29-0
    40642-40-8
    Navel Orangeworm
    Orange
    (Z,Z)-11,13-Hexadecadienal (000711)
    71317-73-2
    Obliquebanded leafroller
    Fruit
    Lauryl alcohol (001509)
    Myristyl alcohol (001510)
    (E,E) -8,10-Dodecadien-1-ol (129028)
    (Z) -11-Tetradecenyl acetate (128980)
    112-53-8
    112-72-1
    33956-49-9
    20711-10-8
    Omnivorous leafroller
    Fruit (deciduous)
    Grapes
    Kiwi
    Nuts
    (E)-11-Tetradecenyl acetate (129019)
    (Z)-11-Tetradecenyl acetate (128980)
    33189-72-9
    20711-10-8
    Oriental fruit moth
    Fruit
    Nuts
    (Z)-8-Dodecen-1-yl acetate (128906)
    (E)-8-Dodecen-1-yl-acetate (128907)
    28079-04-1
    38363-29-0
    40642-40-8
    Oriental fruit moth
    Fruit
    Nuts
    (E)-5-Decenyl acetate (117703)
    (E)-5-Decen-1-ol (078038)
    (Z)-8-Dodecen-1-yl acetate (128906)
    (E)-8-Dodecen-1-yl-acetate (128907)
    (Z)-8-Dodecen-1-ol (128908)
    38421-90-8
    56578-18-8
    28079-04-1
    38363-29-0
    40642-40-8
    Pandemis leafroller
    Fruit
    Lauryl alcohol (001509)
    Myristyl alcohol (001510)
    (E,E) -8,10-Dodecadien-1-ol (129028)
    (Z) -11-Tetradecenyl acetate (128980)
    112-53-8
    112-72-1
    33956-49-9
    20711-10-8
    Peach twig borer
    Fruit
    Nuts
    (E)-5-Decenyl acetate (117703)
    (E)-5-Decen-1-ol (078038)
    (Z)-8-Dodecen-1-yl acetate (128906)
    (E)-8-Dodecen-1-yl-acetate (128907)
    (Z)-8-Dodecen-1-ol (128908)
    38421-90-8
    56578-18-8
    28079-04-1
    38363-29-0
    40642-40-8
    Peach twig borer
    Fruit
    Nuts
    Agricultural crops (unspecified)
    (E)-5-Decen-1-ol acetate (117703)
    (E)-5-Decen-1-ol (078038)
    38421-90-8
    56578-18-8
    Pink bollworm
    Cotton
    7,11-Hexadecadien-1-ol acetate (114103)
    50933-33-0
    Pink bollworm
    Cotton
    (Z,E)-7,11-Hexadecadien-1-yl acetate (114101)
    (Z,Z)-7,11- Hexadecadien-1-yl acetate (114102)
    53042-79-8
    52207-99-5
    Sparganothis fruitworm
    Cranberries
    (E)-11-Tetradecen-1-ol acetate (129019)
    33189-72-9
    Tomato pinworm
    Eggplant
    Tomato
    Vegetables (fruiting)
    (Z)-4-Tridecen-1-yl acetate (121901)
    (E)-4-Tridecen-1-yl acetate (121902)
    65954-19-0
    72269-48-8
    Western Poplar Clearwing moth (Paranthrene robiniae)
    Poplars
    White Birch
    Willows
    Locust
    (E,Z)-3,13-octadecadien-1-ol
    (Z,Z)-3,13-octadecadien-1-ol
    66410-28-4
    66410-24-0

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