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RNAi White Paper Published in Advance of January 28 Scientific Advisory Panel Meeting

For Release: January 17, 2014

The EPA has posted a paper, "RNAi Technology as a Pesticide: Problem Formulation for Human Health and Ecological Risk Assessment," and the charge to the Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) for the January 28, 2014, SAP meeting.
 
The agency will consult with the SAP on the EPA’s approach to assess the risk of RNAi gene silencing technology for pesticidal purposes. In particular, the EPA is seeking advice on evaluating the general uncertainties concerning the pesticidal use of double-stranded RNAs (dsRNAs), including the potential fate of dsRNAs engineered into plants or other organisms in the environment and any avenues through which they may present risk to human health and/or the environment.
 
These background materials and details about the January 28 SAP meeting are available at www.regulations.gov under Docket ID No. EPA-HQ-OPP-2013-0485. Additional information on the SAP can be found at http://www.epa.gov/scipoly/sap/meetings/2014/.

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