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Staff Paper #8.1

EXECUTIVE SUMMARY OF FRAMEWORK
FOR REFINING FQPA SCIENCE POLICIES

The following science policy areas are described in the attached matrix. The matrix provides information on EPA's current approach to each issue in risk assessment, as well as plans for obtaining additional comment on the approach, and the timing of that comment process or completion of a relevant document. We are asking the TRAC to provide suggestions for improving transparency related to each area.

  1. Applying the FQPA 10-fold safety factor
  2. Exposure assessment--whether and how to use Monte Carlo analyses
  3. Exposure assessment--interpreting "no residues detected"
  4. Dietary exposure estimates
  5. Drinking water exposures
  6. Assessing residential exposure
  7. Aggregating exposures from all non-occupational sources
  8. How to conduct a cumulative risk assessment for organophosphates or other common mechanism pesticides

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updated June 19, 1998