Inert (other) Pesticide Ingredients in Pesticide Products - Categorized List of Inert (other) Pesticide Ingredients
- Inert (other) Ingredients in Pesticides Products
- About Tolerance Reassessment
- Reassessment Status List
- Categorized List of Inert (other) Pesticide Ingredients
- Federal Register and Pesticide Registration Notices on Inert (other)
- Guidance for Supporting the Inert Ingredients Subject to the Revocation Notice of 8/9/2006 (250KB, 5pp., PDF)
- Tips for Inert Ingredients (DRAFT) (230KB, 4pp., PDF)
- Fragrance Notification Pilot Program(41KB, 6pp., PDF)
- Fragrance Ingredient List(2MB, 45pp., PDF)
- Fragrance Formula Sheet (19KB, .xls file)
- Joint Inerts Task Force (JITF) Formed to Support Revoked Inert Ingredients (24KB, 1pp., PDF)
Inerts Ingredient Assessment Branch, Inerts Team
For an inert ingredient to be included in a food-use pesticide product, a tolerance exemption must be established in the appropriate section of 40 CFR 180 subpart D.
Categorized Lists - OPP published a policy statement on inert ingredients in 1987. 52 FR 13305, Inert Ingredients in Pesticide Products Policy Statement (04/22/87)). The policy established four categories of toxicological concern for the inert ingredients in existence at that time. In 1989, List 4 "Inerts of Minimal Concern" was subdivided into List A and List 4B (see 54 FR 48314, Inert Ingredients in Pesticide Products; Policy Statement; Revision and Modification List (11/22/89)).
NOTE: You will need Adobe Acrobat Reader, available as a free download, to view the files in this list. See EPA's PDF page to learn more about PDF, and for a link to the free Acrobat Reader.
Note: This information is provided for reference purposes only. Although the information provided here was accurate and current when first created, it is now outdated.
The following contains a listing of all the "inert" or "other ingredients" found in pesticide products registered by EPA.
This is the complete list sorted by CAS Number (311KB, PDF) or chemical name (440KB, PDF).
List 1: Inert Ingredients of Toxicological Concern.
- Classified on the basis of peer-reviewed studies which demonstrated carcinogenicity, adverse reproductive effects, neurotoxicity or other chronic effects, developmental toxicity (birth defects), ecological effects or the potential for bioaccumulation.
- Products containing a List 1 inert ingredient must include the label statement "This product contains the toxic inert ingredient (name of inert)."
- Sorted by chemical abstract service number (11KB, 2pp., PDF)
- Sorted by chemical name (49KB, 2pp., PDF)
- Original listing of List 1 inert ingredients contained over 50 chemical substances. Today approximately 10 of these substances are still used in pesticide products.
List 2: Potentially Toxic Other Ingredients/High Priority for Testing inerts.
- Many List 2 inert ingredients are structurally similar to chemicals known to be toxic; some have data suggesting a concern.
- Sorted by chemical abstract service number (91KB, 2pp., PDF)
- Sorted by chemical name (25KB, 4pp., PDF)
List 3: Inerts of unknown toxicity.
- An inert ingredient was placed on List 3 if there was no basis for listing it on any of the other lists. The Agency will continue to evaluate these chemical substances, as additional information becomes available, to determine if reclassification to List 1, 2, or 4 is appropriate.
- Sorted by chemical abstract service number (200KB, 39pp., PDF)
- Sorted by chemical name (202KB, 39pp., PDF)
List 4A: Minimal risk inert ingredients.
- The determination that a chemical is minimal risk would be based on a recognition of the overall safety of the chemical (such as very low toxicity or practically non-toxic) considering the widely available information on the chemical's known properties, and a history of safe use under reasonable circumstances.
- Minimal risk (List 4A) substances are recognized as safe for use in all pesticide products subject only to good agricultural or good manufacturing practices since the Agency does not establish any restrictions on use patterns (how, where, when or in what manner the substance can be used) or limit the amount of a List 4A chemical substance that can be used as an inert ingredient in a pesticide product. It is noted that for a food-use application, the necessary tolerance exemption must be established. The substances on List 4A are the only inert ingredients that can be used in Federal Insecticide, Fungicide and Rodenticide Act (FIFRA) section 25(b) deregulated or exempted products (see 40 CFR 152.25(f)(2)). Under FIFRA 25(b) the Agency does not review and evaluate the labeling for these products, and therefore cannot require the use of protective equipment.
- Sorted by chemical abstract service number (48KB, 7pp., PDF)
- Sorted by chemical name list 4A (46KB, 7pp., PDF)
List 4B: Other ingredients for which EPA has sufficient information to reasonably conclude that the current use pattern in pesticide products will not adversely affect public health or the environment.
- In making a List 4B determination, the Agency evaluates not only the toxicity of the chemical substance, but also considers the particular exposures that could occur and the need for any restrictions.
- The two critical distinctions between List 4A minimal risk substances and List 4B substances, are that while the Agency does not establish a use pattern or use limitation for a List 4A chemical substance, a List 4B may have such restrictions. Also, List 4 chemicals that are chemicals of higher acute toxicity are generally classified as List 4B, so that the Agency can evaluate the labeling and require the use of protective equipment.The substances on List 4B have no relevance to the provisions in FIFRA 25(b) for deregulated or exempted products.
- Sorted by chemical abstract service number (159KB, 18pp., PDF)
- Sorted by chemical name list 4B (189KB, 18pp., PDF)