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Technical Tools Used in the Derivation of AEGLs

Benchmark Dose Methodology and other tools - The Benchmark Dose Methodology estimates the threshold concentration corresponding to a level of benchmark response.

Ten Berge's Dose-Response application Exit EPA Disclaimer - calculates concentration-time response relationships at a specified response.

PBPK white paper - This document describes the methods for integrating physiologically based pharmacokinetic (PBPK) modeling in the development of AEGLs.


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