HPV Challenge Program
More on Managing Existing Chemicals
- HPV Challenge Program
- HPVIS - Making HPV Available Online
- Inventory Update Reporting
- Chemical Nanoscale Materials
- Managing Potential PFOA Risks
- Potential Chemical Risks to Children
- Section 21 Petitions
- Using TSCA Section 8(e)
- TSCA Section 12(b) Export Notifications
- International Work
- OECD HPV Chemicals Program
Under Goal Four of EPA's Strategic Plan, EPA has committed, by 2011, to eliminate or effectively manage risks associated with 100 percent of High Production Volume (HPV) chemicals for which unreasonable risks have been identified through EPA risk assessments. (Baseline: EPA screening of data obtained through the HPV Challenge Program commenced in 2006; actions to obtain additional information needed to assess risks will commence as chemicals are identified as priority concerns through the screening process.)
The purpose of the High Production Volume (HPV) Challenge Program is to ensure that basic health and environmental effects data on HPV chemicals are made available to the public. HPV chemicals are considered to be those manufactured or imported in amounts equal to or greater than 1 million pounds per year. A basic premise of the program is that the public has a right to know about the hazards associated with chemicals in their environment and that this information helps them to make wise choices in selecting which chemicals or consumer products to use.
EPA is expanding its HPV Challenge Program work and is extending its efforts to moderate production volume (MPV) chemicals. These efforts will be implemented under the new Chemical Assessment and Management Program (ChAMP). For more information about this program, read the ChAMP section of this report.
Since the HPV Challenge Program's inception in 1998, industry chemical manufacturers and importers have participated by sponsoring nearly 2,250 chemicals. Sponsorship involves a commitment to develop data summaries of relevant existing information and to conduct testing to fill any data gaps. More than 350 companies and 100 consortia have sponsored 1,386 chemicals directly in the program, and an additional 857 chemicals have been sponsored indirectly in an international counterpart to the HPV Challenge Program: the International Council of Chemical Associations (ICCA) HPV Initiative. EPA issued an interim report entitled Status and Future Directions of the High Production Volume (HPV) Challenge Program in November 2004 that includes background and a description of the program.
In an effort to increase accessibility to HPV data, OPPT launched the HPV Information System (HPVIS) Web database in 2006 to allow users to easily and comprehensively search for specific HPV chemical property data, and OPPT continues its effort to fully populate the Web database.
OPPT also has contributed to the development and release of the Organization for Economic Cooperation and Development’s eChemPortal, which also provides public access to information on the properties, hazards and risks of chemicals.
In 2007, EPA began focusing its efforts on how to use the collected HPV Challenge Program data by developing screening-level hazard characterizations. These hazard characterizations give the public an objective evaluation of the quality, completeness, and significance of the data. By June 2008, the Agency posted hazard characterizations for 275 chemicals to its Web site.
In addition to hazard characterizations, in 2007, EPA began developing screening-level exposure characterizations and risk characterizations that were used to produce initial risk-based prioritization documents for HPV chemicals. By June 2008, the Agency posted risk-based prioritizations for 19 chemicals to its Web site and will continue to develop and post prioritizations for additional chemicals.
In March 2008, EPA created the Chemical Assessment and Management Program (ChAMP), broadening its HPV Challenge Program and extending its efforts to include moderate production volume chemicals, which are those produced in quantities greater than 25,000 pounds and less than 1 million pounds per year. ChAMP is the program that encompasses hazard characterizations and prioritizations on chemicals for possible risk management actions. Read the ChAMP section of this report for more information about the program. For information on the progress of these documents, visit the ChAMP Web site.
- As part of its HPV Challenge Program and HPVIS database outreach, EPA staffed a booth in 2007 at conferences, including the Society of Toxicology conference in Charlotte, N.C., and the Society of Environmental Toxicology and Chemistry conference in Milwaukee, Wisc.
- By the end of June 2008, data for 1,008 of the approximately 1,400 chemicals sponsored directly in the program had been entered into HPVIS. Read the HPVIS section of this report for more information.
- The Agency is currently addressing 15 chemicals that have been sponsored but for which test plans or completed data summaries have not been submitted to EPA.
To further address "orphan" chemicals that were eligible for sponsorship but are not sponsored, EPA developed a second HPV test rule in 2007, and this proposed rule is scheduled for publication in 2008.
- Data are also being developed from industry for an additional 208 orphan chemicals covered under the TSCA 8(a) Preliminary Assessment Information Reporting (PAIR) and TSCA 8(d) Health and Safety Data Reporting Rules that were published in 2006. The Agency has received PAIR reports for 86 of the 208 chemicals, and has received health and safety study submissions for 54 of the 208 chemical substances; for both rules, EPA is evaluating the collected information.