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Methyl Ethyl Ketoxime (MEKO) Test Results
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JITC Recommendation - Nineteenth Report
51 FR 41417; November 14, 1986
Proposed Test Rule (PRM)
53 FR 35838; September 15, 1988
Final Test Rule (FRM)
54 FR 37799; September 13, 1989
Corrections
54 FR 49844; December 1, 1989
Project Manager: R. Jones
Section Chief: F. Benenati
Status: Closed. All required tests have been completed. Test results have been forwarded to the Risk Assessment Division for review and disposition. Attachment A for information on voluntary Product Stewardship Program activities relating to this chemical.
Announced Receipt of Test Data
The Industry Health Foundation, Inc. (IHF) submitted an acute in-vivo cytogenetic assay in rats (56 FR 2924; January 25, 1991).
Industry Health Foundation, Inc. submissions included a supplementary probe 6-week inhalation toxicity study, a sex-linked recessive lethal test in Drosophila melanogaster, an acute motor activity study in rats, and an acute neurotoxicity study in rats (56 FR 22715; May 16, 1991).
IHF submitted a subchronic neurotoxicity study in rats (56 FR 33931; July 24, 1991).
A 2-generation reproductive study in rats was received from IHF (57 FR 17907; April 28, 1992).
IHF submitted a study described as “Inhalation oncogenicity study of MEKO in rats and mice; Part I - mice” that was received by EPA on November 9, 1993 (58 FR 65353; December 14, 1993).
IHF submitted a study described as “Inhalation oncogenicity study of MEKO in rats and mice; Part II - rats” that was received by EPA on March 24, 1994 (59 FR 23061; May 4, 1994).
Results of Testing Table