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Format, Headings and Codes for the Master Testing List

Note: EPA no longer updates this information, but it may be useful as a reference or resource.

The MTL is reflected in 2 complementary indices. The first index ("INDEX I. MASTER TESTING LIST") is a "master" index of all chemicals and categories currently on the MTL as well as those chemicals/categories that have been removed from the MTL since 1992. The second index ("INDEX II. CHEMICALS REMOVED FROM THE MTL") includes only those chemicals that have been removed from the MTL since 1992 and provides the rationale for their removal. All of the chemicals on the MTL indices are ordered by ascending Chemical Abstract Service (CAS) Registry Numbers. Those chemicals and categories that do not have CAS Numbers appear at the beginning of each index. A description of the index columns as they are ordered from left to right follows.

CAS Number:
This unique identifier of up to 9 digits is assigned to chemicals by the Chemical Abstract Service (CAS). CAS Numbers are not available for several chemical substances (e.g., commercial hexane) nor are they available for the categories listed on the MTL. As stated above, chemicals lacking CAS numbers, as well as categories (which have no CAS Numbers), are found at the beginning of each index.
Chemical Name:
The common chemical name used by EPA.
The chemicals/categories on the MTL have been recommended for testing by sources from within EPA, other Federal agencies, the TSCA Interagency Testing Committee (ITC), and the international toxics community. For a number of chemical substances, there are several sources of the testing recommendations identified. All of the sources are listed separately in each of the MTL indices and include the following:
U.S. Agency for Toxic Substances and Disease Registry
U.S. Consumer Product Safety Commission
U.S. Department of the Interior
TSCA Interagency Testing Committee (ITC). The ITC was created under section 4 of TSCA and is mandated to recommend chemical substances to EPA for testing consideratino. The ITC recommends these chemicals in twice-yearly formal reports to the EPA Administrator. This code also indicates the ITC Report number in which the chemical was designated for testing. For example, the source code "ITC/16" indicates that the subject chemical substance was designated for testing consideration in the ITC's 16th Report to the EPA Administrator.
Office of Air and Radiation, US EPA
Hazardous Air Pollutants
Oxygenated Fuel Additives
Organization for Economic Cooperation and Development. OECD member nations have agreed that certain international high production volume chemicals should have a "base set" of screening level test data. This base set is referred to as the Screening Information Data Set (SIDS).

  Further information about the OECD SIDS Testing Program

The table below identifies the OECD member country or countries sponsoring the international high production volume chemicals that have been selected for SIDS testing. Under this voluntary program, the sponsor first prepares a data summary or "Dossier" and then conducts testing designed to provide the missing SIDS data. Countries handling the chemicals are identified by 2-letter codes. These codes and their corresponding countries are listed in Table 1. For those chemicals being handled under the European Union's testing program, the code "EU" appears. For those chemicals selected for Post-SIDS testing, the acronym "BIAC" appears in place of the sponsoring country and refers to the OECD's "Business and Industry Advisory Committee."

OECD and EU Countries and Codes

Australia AU
Austria* AT
Belgium* BE
Canada CA
Switzerland CH
Germany* DE
Denmark* DK
Finland* FI
France* FR
Italy* IT
Japan JP
Netherlands* NL
Norway NO
Spain* SP
Sweden* SE
United Kingdom* UK
United States US
*European Union Members EU
Other EU Member Countries:

Greece, Ireland, Luxembourg, Portugal

Office of Pollution Prevention and Toxics, USEPA. OPPT has identified existing chemical substances and categories of chemicals in need of testing through its TSCA Existing Chemicals Program and also via its TSCA New Chemicals Program. Those chemicals and categories of chemicals of specific interest to OPPT are found in the following testing actions that are listed on the MTL:
Aniline/Substituted Anilines
Carpet/Carpet Products
Dioxins/Furans in Organic Chemicals Rule
Dioxins/Furans in Pulp and Paper Mill Sludge
Endocrine Disruptors
Interior Architectural Coatings
Machining Fluids
Neurotoxicity Endpoint Rule
New Chemicals Program - Categories of Concern
      CFCS :
Chlorofluorocarbon Substitutes
Fluorescent Whitening Agents
Vinyl Esters
Nonyl Phenol
Paint Strippers - DBE - DiBasic Esters
Persistent Bioaccumulators
Reproductive/Developmental Toxicity Endpoint Rule
Respirable Fibers
Toxic Release Inventory Chemicals
Office of Water, USEPA.
Office of Drinking Water Chemicals
Year Added or Removed:
The year in which a chemical substance or category was added to or removed from the MTL.
One of the following program status codes accompanies each of the chemicals or categories listed on the MTL:
Testing Needs Development Underway - indicates that EPA is in the process of determining the testing needs for a given chemical or chemicals within a listed category. Upon identification of specific
testing needs, EPA initiates development of a testing action for the subject chemical(s) or category as described in the following paragraph.
esting Action Development Underway - indicates that EPA is initiating development of a testing action via TSCA Section 4 Final Rule-Making (FRM), a TSCA Section 4 Enforceable Consent Agreement (ECA), or a Voluntary Testing Agreement (VTA).
Chemical Testing Program Underway - CTPU indicates that the chemical testing program is currently underway by way of an FRM, ECA, or VTA.
Removed: Removed from MTL:
"Removed" indicates that the subject chemical substance or category has been deleted from the MTL and the year of the removal. If Index I. indicates that a chemical or category has been removed from the MTL, Index II. (which is a list of those chemicals or categories removed from the MTL since 1992) should be consulted for the specific rationale for that removal. The rationale and additional comments regarding the subject chemical appear in the far right columns in Index II.
Testing Needs:
The last 3 columns of Index I. indicate specific testing needs for health effects (Health), environmental effects (Environ) and environmental fate/exposure (Fate). The table below lists the codes for specific testing needs for the individual chemicals and categories listed on the MTL.

Testing Need Codes

Health Effects
Environmental Effects
Environmental Fate
ACUTE Acute Toxicity ACUTE Acute Toxicity BIOC
CARC Carcinogenicity CHR Chronic Toxicity DEGR
CHR Chronic Toxicity SIDS Screening Data MONIT
DEVEL Developmental Toxicity OTHR Other PCHM
DNEURO Developmental Neurotoxicity TSPT
EPID Epidemiology SIDS
IMMUN Immunotoxicity
MUTA Mutagenicity
NEURO Neurotoxicity OTHR
PK Pharmocokinetics
PCHR Prechronic Toxicity/14-28 day
REPRO Reproductive
SCHR Subchronic toxicity/90 day
SIDS Screening Data
Skin Absorption Rate

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