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Significant New Uses of Certain Chemical Substances

[Federal Register: December 17, 2003 (Volume 68, Number 242)]
[Rules and Regulations]               
[Page 70155-70184]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr17de03-16]                         

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ENVIRONMENTAL PROTECTION AGENCY

40 CFR Part 721

[OPPT-2002-0078; FRL-7307-3]
RIN 2070-AB27

 
Significant New Uses of Certain Chemical Substances

AGENCY: Environmental Protection Agency (EPA).

ACTION: Direct final rule.

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SUMMARY: EPA is promulgating significant new use rules (SNURs) under 
section 5(a)(2) of the Toxic Substances Control Act (TSCA) for 65 
chemical substances which were the subject of premanufacture notices 
(PMNs) and subject to TSCA section 5(e) consent orders issued by EPA. 
This action requires persons who intend to manufacture, import, or 
process these chemical substances for a significant new use to notify 
EPA at least 90 days before commencing the manufacturing or processing 
of the chemical substance for a use designated by this rule as a 
significant new use. The required notification will provide EPA with 
the opportunity to evaluate the intended

[[Page 70156]]

use, and if necessary, to prohibit or limit that activity before it 
occurs to prevent any unreasonable risk of injury to human health or 
the environment.

DATES: The effective date of this rule is February 17, 2004, without 
further notice, unless EPA receives adverse or critical comments, or 
notice of intent to submit adverse or critical comments before January 
16, 2004. This rule shall be promulgated for purposes of judicial 
review at 1 p.m. (e.s.t.) on December 31, 2003.
    If EPA receives adverse or critical comments or notice of intent to 
submit adverse or critical comments before January 16, 2004, on EPA's 
action in establishing a SNUR for one or more of the chemical 
substances subject to this rule, EPA will withdraw the SNUR before the 
effective date for the chemical substance for which the adverse or 
critical comment or notice of intent to submit adverse or critical 
comment is received and will issue a proposed SNUR providing a 30-day 
period for public comment.

ADDRESSES: Adverse or critical comments or notice of intent to submit 
adverse or critical comments may be submitted electronically, by mail, 
or through hand delivery/courier. Follow the detailed instructions as 
provided in Unit I. of the SUPPLEMENTARY INFORMATION.

FOR FURTHER INFORMATION CONTACT: For general information contact: 
Barbara Cunningham, Director, Environmental Assistance Division 
(7408M), Office of Pollution Prevention and Toxics, Environmental 
Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460-
0001; telephone number: (202) 554-1404; e-mail address: 
TSCA-Hotline@epa.gov.
    For technical information contact: James Alwood, Chemical Control 
Division (7405M), Office of Pollution Prevention and Toxics, 
Environmental Protection Agency, 1200 Pennsylvania Ave., NW., 
Washington, DC 20460-0001; telephone number: (202) 564-8974, e-mail 
address: alwood.jim@epa.gov.

SUPPLEMENTARY INFORMATION:

I. General Information

A. Does this Action Apply to Me?

    You may be potentially affected by this action if you manufacture, 
import, process, or use the chemical substances contained in this rule. 
Potentially affected entities may include, but are not limited to:

    [sbull] Chemical manufacturers (NAICS 325), e.g., Manufacturers, 
importers, processors, and users of chemicals
    [sbull] Petroleum and coal product industries (NAICS 324), e.g., 
Manufacturers, importers, processors, and users of chemicals

    This listing is not intended to be exhaustive, but rather provides 
a guide for readers regarding entities likely to be affected by this 
action. Other types of entities not listed in this unit could also be 
affected. The North American Industrial Classification System (NAICS) 
codes have been provided to assist you and others in determining 
whether this action might apply to certain entities. To determine 
whether you or your business may be affected by this action, you should 
carefully examine the applicability provisions in 40 CFR 721.5. If you 
have any questions regarding the applicability of this action to a 
particular entity, consult the technical person listed under FOR 
FURTHER INFORMATION CONTACT.

B. How Can I Get Copies of this Document and Other Related Information?

    1. Docket. EPA has established an official public docket for this 
action under docket identification (ID) number OPPT-2002-0078. The 
official public docket consists of the documents specifically 
referenced in this action, any public comments received, and other 
information related to this action. Although a part of the official 
docket, the public docket does not include Confidential Business 
Information (CBI) or other information whose disclosure is restricted 
by statute. The official public docket is the collection of materials 
that is available for public viewing at the EPA Docket Center, Rm. 
B102-Reading Room, EPA West, 1301 Constitution Ave., NW., Washington, 
DC. The EPA Docket Center is open from 8:30 a.m. to 4:30 p.m., Monday 
through Friday, excluding legal holidays. The EPA Docket Center Reading 
Room telephone number is (202) 566-1744 and the telephone number for 
the OPPT Docket, which is located in EPA Docket Center, is (202) 566-
0280.
    2. Electronic access. You may access this Federal Register document 
electronically through the EPA Internet under the "Federal Register" 
listings at http://www.gpo.gov/fdsys/search/home.action The OPPTS harmonized test guidelines referenced in this document are available at http://www.epa.gov/
opptsfrs/home/guidelin.htm/.

http://www.epa.gov/opptsfrs/home/guidelin.htm. A frequently updated 

electronic version of 40 CFR part 721 is available at http://www.access.gpo.gov/nara/cfr/cfrhtml_00/Title_40/40cfr721_00.html/
, a 

beta site currently under development.
    An electronic version of the public docket is available through 
EPA's electronic public docket and comment system, EPA Dockets. You may 
use EPA Dockets at http://www.epa.gov/edocket/ to submit or view public 

comments, access the index listing of the contents of the official 
public docket, and to access those documents in the public docket that 
are available electronically. Although not all docket materials may be 
available electronically, you may still access any of the publicly 
available docket materials through the docket facility identified in 
Unit I.B.1. Once in the system, select "search," then key in the 
appropriate docket ID number.
    Certain types of information will not be placed in the EPA Dockets. 
Information claimed as CBI and other information whose disclosure is 
restricted by statute, which is not included in the official public 
docket, will not be available for public viewing in EPA's electronic 
public docket. EPA's policy is that copyrighted material will not be 
placed in EPA's electronic public docket but will be available only in 
printed, paper form in the official public docket. To the extent 
feasible, publicly available docket materials will be made available in 
EPA's electronic public docket. When a document is selected from the 
index list in EPA Dockets, the system will identify whether the 
document is available for viewing in EPA's electronic public docket. 
Although not all docket materials may be available electronically, you 
may still access any of the publicly available docket materials through 
the docket facility identified in Unit I.B.1. EPA intends to work 
towards providing electronic access to all of the publicly available 
docket materials through EPA's electronic public docket.
    For public commenters, it is important to note that EPA's policy is 
that public comments, whether submitted electronically or in paper, 
will be made available for public viewing in EPA's electronic public 
docket as EPA receives them and without change, unless the comment 
contains copyrighted material, CBI, or other information whose 
disclosure is restricted by statute. When EPA identifies a comment 
containing copyrighted material, EPA will provide a reference to that 
material in the version of the comment that is placed in EPA's 
electronic public docket. The entire printed comment, including the 
copyrighted material, will be available in the public docket.
    Public comments submitted on computer disks that are mailed or 
delivered to the docket will be transferred to EPA's electronic public

[[Page 70157]]

docket. Public comments that are mailed or delivered to the docket will 
be scanned and placed in EPA's electronic public docket. Where 
practical, physical objects will be photographed, and the photograph 
will be placed in EPA's electronic public docket along with a brief 
description written by the docket staff.

C. How and to Whom Do I Submit Comments?

    You may submit comments electronically, by mail, or through hand 
delivery/courier. To ensure proper receipt by EPA, identify the 
appropriate docket ID number in the subject line on the first page of 
your comment. Please ensure that your comments are submitted within the 
specified comment period. Comments received after the close of the 
comment period will be marked "late." EPA is not required to consider 
these late comments. If you wish to submit CBI or information that is 
otherwise protected by statute, please follow the instructions in Unit 
I.D. Do not use EPA Dockets or e-mail to submit CBI or information 
protected by statute.
    1. Electronically. If you submit an electronic comment as 
prescribed in this unit, EPA recommends that you include your name, 
mailing address, and an e-mail address or other contact information in 
the body of your comment. Also include this contact information on the 
outside of any disk or CD ROM you submit, and in any cover letter 
accompanying the disk or CD ROM. This ensures that you can be 
identified as the submitter of the comment and allows EPA to contact 
you in case EPA cannot read your comment due to technical difficulties 
or needs further information on the substance of your comment. EPA's 
policy is that EPA will not edit your comment, and any identifying or 
contact information provided in the body of a comment will be included 
as part of the comment that is placed in the official public docket, 
and made available in EPA's electronic public docket. If EPA cannot 
read your comment due to technical difficulties and cannot contact you 
for clarification, EPA may not be able to consider your comment.
    i. EPA Dockets. Your use of EPA's electronic public docket to 
submit comments to EPA electronically is EPA's preferred method for 
receiving comments. Go directly to EPA Dockets at http://www.epa.gov/edocket/
, and follow the online instructions for submitting comments. 

Once in the system, select "search," and then key in docket ID number 
OPPT-20027-0078. The system is an "anonymous access" system, which 
means EPA will not know your identity, e-mail address, or other contact 
information unless you provide it in the body of your comment.
    ii. E-mail. Comments may be sent by e-mail to oppt.ncic@epa.gov, 
Attention: Docket ID Number OPPT-2002-0078. In contrast to EPA's 
electronic public docket, EPA's e-mail system is not an "anonymous 
access" system. If you send an e-mail comment directly to the docket 
without going through EPA's electronic public docket, EPA's e-mail 
system automatically captures your e-mail address. E-mail addresses 
that are automatically captured by EPA's e-mail system are included as 
part of the comment that is placed in the official public docket, and 
made available in EPA's electronic public docket.
    iii. Disk or CD ROM. You may submit comments on a disk or CD ROM 
that you mail to the mailing address identified in Unit I.C.2. These 
electronic submissions will be accepted in WordPerfect or ASCII file 
format. Avoid the use of special characters and any form of encryption.
    2. By mail. Send your comments to: Document Control Office (7407M), 
Office of Pollution Prevention and Toxics (OPPT), Environmental 
Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460-
0001.
    3. By hand delivery or courier. Deliver your comments to: OPPT 
Document Control Office (DCO) in EPA East Bldg., Rm. 6428, 1201 
Constitution Ave., NW., Washington, DC. Attention: Docket ID Number 
OPPT-2002-0078. The DCO is open from 8 a.m. to 4 p.m., Monday through 
Friday, excluding legal holidays. The telephone number for the DCO is 
(202) 564-8930.

D. How Should I Submit CBI to the Agency?

    Do not submit information that you consider to be CBI 
electronically through EPA's electronic public docket or by e-mail. You 
may claim information that you submit to EPA as CBI by marking any part 
or all of that information as CBI (if you submit CBI on disk or CD ROM, 
mark the outside of the disk or CD ROM as CBI and then identify 
electronically within the disk or CD ROM the specific information that 
is CBI). Information so marked will not be disclosed except in 
accordance with procedures set forth in 40 CFR part 2.
    In addition to one complete version of the comment that includes 
any information claimed as CBI, a copy of the comment that does not 
contain the information claimed as CBI must be submitted for inclusion 
in the public docket and EPA's electronic public docket. If you submit 
the copy that does not contain CBI on disk or CD ROM, mark the outside 
of the disk or CD ROM clearly that it does not contain CBI. Information 
not marked as CBI will be included in the public docket and EPA's 
electronic public docket without prior notice. If you have any 
questions about CBI or the procedures for claiming CBI, please consult 
the technical person listed under FOR FURTHER INFORMATION CONTACT.

E. What Should I Consider as I Prepare My Comments for EPA?

    We invite you to provide your views on the various options in this 
document, new approaches we haven't considered, the potential impacts 
of the various options (including possible unintended consequences), 
and any data or information that you would like the Agency to consider 
during the development of the final action. You may find the following 
suggestions helpful for preparing your comments:
    1. Explain your views as clearly as possible.
    2. Describe any assumptions that you used.
    3. Provide copies of any technical information and/or data you used 
that support your views.
    4. If you estimate potential burden or costs, explain how you 
arrived at the estimate that you provide.
    5. Provide specific examples to illustrate your concerns.
    6. Offer alternative ways to improve the rule.
    7. Make sure to submit your comments by the deadline in this 
document.
    8. To ensure proper receipt by EPA, be sure to identify the docket 
ID number assigned to this action in the subject line on the first page 
of your response. You may also provide the name, date, and Federal 
Register citation.

II. Background

A. What Action is the Agency Taking?

    EPA is promulgating this SNUR using direct final procedures. This 
SNUR will require persons to notify EPA at least 90 days before 
commencing manufacturing, importing, or processing a chemical substance 
for any activity designated by this SNUR as a significant new use. The 
supporting rationale and background to this rule are more fully set out 
in the preamble to EPA's first direct final SNUR published in the 
Federal Register of April 24, 1990 (55 FR 17376). Consult that preamble 
for further information on the objectives, rationale, and procedures 
for the rules and on the basis for significant new use designations 
including provisions for developing test data.

[[Page 70158]]

B. What is the Agency's Authority for Taking this Action?

    Section 5(a)(2) of TSCA (15 U.S.C. 2604(a)(2)) authorizes EPA to 
determine that a use of a chemical substance is a "significant new 
use." EPA must make this determination by rule after considering all 
relevant factors, including those listed in TSCA section 5(a)(2). Once 
EPA determines that a use of a chemical substance is a significant new 
use, TSCA section 5(a)(1)(B) requires persons to submit a notice to EPA 
at least 90 days before they manufacture, import, or process the 
chemical substance for that use. The mechanism for reporting under this 
requirement is established under 40 CFR 721.5.

C. Applicability of General Provisions

    General provisions for SNURs appear under subpart A of 40 CFR part 
721. These provisions describe persons subject to the rule, 
recordkeeping requirements, exemptions to reporting requirements, and 
applicability of the rule to uses occurring before the effective date 
of the final rule. Provisions relating to user fees appear at 40 CFR 
part 700. Persons subject to this SNUR must comply with the same notice 
requirements and EPA regulatory procedures as submitters of PMNs under 
TSCA section 5(a)(1)(A). In particular, these requirements include the 
information submission requirements of TSCA section 5(b) and 5(d)(1), 
the exemptions authorized by TSCA section 5(h)(1), (h)(2), (h)(3), and 
(h)(5), and the regulations at 40 CFR part 720. Once EPA receives a 
SNUR notice, EPA may take regulatory action under TSCA section 5(e), 
5(f), 6, or 7 to control the activities on which it has received the 
SNUR notice. If EPA does not take action, EPA is required under TSCA 
section 5(g) to explain in the Federal Register its reasons for not 
taking action.
    Persons who intend to export a chemical substance identified in a 
proposed or final SNUR are subject to the export notification 
provisions of TSCA section 12(b). The regulations that interpret TSCA 
section 12(b) appear at 40 CFR part 707. Persons who intend to import a 
chemical substance identified in a final SNUR are subject to the TSCA 
section 13 import certification requirements, which appear at 19 CFR 
12.118 through 12.127 and 127.28. Such persons must certify that they 
are in compliance with SNUR requirements. The EPA policy in support of 
the import certification appears at 40 CFR part 707.

III. Substances Subject to this Rule

    EPA is establishing significant new use and recordkeeping 
requirements for the following chemical substances under 40 CFR part 
721, subpart E. In this unit, EPA provides a brief description for each 
chemical substance, including its PMN number, chemical name (generic 
name if the specific name is claimed as CBI), CAS number (if assigned 
for non-confidential chemical identities), basis for the action taken 
by EPA in the TSCA section 5(e) consent order or as a non-section 5(e) 
SNUR for the chemical substance (including the statutory citation and 
specific finding), toxicity concern, and the CFR citation assigned in 
the regulatory text section of this rule. The specific uses which are 
designated as significant new uses are cited in the regulatory text 
section of this document by reference to 40 CFR part 721, subpart E 
where the significant new uses are described in detail. Certain new 
uses, including production limits and other uses designated in the rule 
are claimed as CBI. The procedure for obtaining confidential 
information is set out in Unit VII.
    Where the underlying TSCA section 5(e) consent order prohibits the 
PMN submitter from exceeding a specified production limit without 
performing specific tests to determine the health or environmental 
effects of a chemical substance, the tests are described in this unit. 
As explained further in Unit VI., the SNUR for such chemical substances 
contains the same production limit, and exceeding the production limit 
is defined as a significant new use. Persons who intend to exceed the 
production limit must notify the Agency by submitting a significant new 
use notice (SNUN) at least 90 days in advance. In addition, this unit 
describes tests that are recommended by EPA to provide sufficient 
information to evaluate the chemical substance, but for which no 
production limit has been established in the TSCA section 5(e) consent 
order. Descriptions of recommended tests are provided for informational 
purposes.
    Data on potential exposures or releases of the chemical substances, 
testing other than that specified in the TSCA section 5(e) consent 
order for the chemical substances, or studies on analogous chemical 
substances, which may demonstrate that the significant new uses being 
reported do not present an unreasonable risk, may be included with 
significant new use notification. Persons submitting a SNUN must comply 
with the same notice requirements and EPA regulatory procedures as 
submitters of PMNs, as stated in 40 CFR 721.1(c), including submission 
of test data on health and environmental effects as described in 40 CFR 
720.50.
    EPA is not publishing SNURs for PMNs 99-255, 99-314, 99-350/351/
352/353, 99-534,99-848, 00-277/278/280, 00-281-285, 00-286-292, 00-502/
503/504, 00-574/575/576/577/608,00-901, 00-1085, 00-1093, 01-558, 01-
584, 01-629, 01-728, 01-757, 01-776, 02-16, 02-195, 02-415, 02-536, 02-
609, and 02-700, which are subject to a final TSCA section 5(e) consent 
order. The TSCA section 5(e) consent orders for these chemical 
substances are derived from an exposure finding based solely on 
substantial production volume and significant or substantial human 
exposure and/or release to the environment of substantial quantities. 
For these cases there were limited or no toxicity data available for 
the PMN substances. In such cases, EPA regulates the new chemical 
substances under TSCA section 5(e) by requiring certain toxicity tests. 
For instance, chemical substances with potentially substantial releases 
to surface waters would be subject to toxicity testing of aquatic 
organisms and chemicals with potentially substantial human exposures 
would be subject to health effects testing for mutagenicity, acute 
effects, and subchronic effects. However, for these chemical 
substances, the short-term toxicity testing required by the TSCA 
section 5(e) consent order is usually completed within 1 to 2 years of 
notice of commencement (NOC). EPA's experience with exposure-based 
SNURs requiring short-term testing is that the SNUR is often revoked 
within 1 to 2 years when the test results are received. Rather than 
issue and revoke SNURs in such a short span of time, EPA will defer 
publication of exposure-based SNURs until either a NOC or data 
demonstrating risk are received unless the toxicity testing required is 
long-term. EPA is issuing this explanation and notification as required 
in 40 CFR 721.160(a)(2) as it has determined that SNURs are not needed 
at this time for these chemical substances which are subject to a final 
section 5(e) consent order under TSCA.

PMN Number P-97-1108
Chemical name: (generic) Polycarboxylic acid ester.
CAS number: Not available.
Basis for action: The PMN substance will be used as a plasticizer. 
Based on structural analogy to esters, EPA is concerned that toxicity 
to aquatic organisms may occur at a concentration as low as 1 part per 
billion (ppb) of the PMN substance in surface waters. Since

[[Page 70159]]

environmental releases are not expected as described in the PMN, EPA 
has not determined that the proposed manufacturing, processing, and use 
of the PMN substance may present an unreasonable risk. EPA has 
determined, however, that release of the PMN substance to surface 
waters may cause significant adverse environmental effects. Based on 
this information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish chronic toxicity 
study (OPPTS 850.1400 test guideline), a daphnid chronic toxicity study 
(OPPTS 850.1300 test guideline), and an algal toxicity study (OPPTS 
850.5400 test guideline) would help to characterize the environmental 
effects of the PMN substance. A porous pot study (OPPTS 835.3220 test 
guideline) would help to characterize possible environmental effects of 
the PMN substance as well.
CFR citation: 40 CFR 721.3110.
PMN Number P-98-848

Chemical name: Silicic acid 
(H6SiO2O7), magnesium strontium 
salt(1:1:2), dysprosium and europium-doped.
CAS number: 181828-07-9.
Effective date of section 5(e) consent order: June 1, 2000.
Basis for section 5(e) consent order: The order was issued under 
section 5(e)(1)(A)(i) and section 5(e)(1)(A)(ii)(I) of TSCA based on a 
finding that the PMN substance may present an unreasonable risk to 
human health.
Recommended testing: EPA has determined that a 90-day subchronic 
inhalation study (OPPTS 870.3465 test guideline) and a 2-year bioassay 
(OPPTS 870.4200) would help to characterize the human health effects of 
the PMN substance.
CFR citation: 40 CFR 721.9511.
PMN Number P-98-1033/1034/1035
Chemical name: (generic) Halogen substituted oxetanes.
CAS number: Not available.
Effective date of section 5(e) consent order: April 6, 1999.
Basis for section 5(e) consent order: The order was issued under 
section 5(e)(1)(A)(i) and section 5(e)(1)(A)(ii)(II) of TSCA based on a 
finding that these PMN substances are expected to be produced in 
substantial quantities, there may be significant or substantial human 
exposure to the PMN substances, and the PMN substances may enter the 
environment in substantial quantities.
Recommended testing: EPA has determined that the following studies 
would help to characterize the health effects of these PMN substances: 
A 28-day oral toxicity study in rats (OPPTS 870.3050) that includes a 
neurotoxicity functional observational battery (National Technical 
Information Service (NTIS): PB 91-154617) for all test doses with the 
highest dose set at 1,000 milligram/kilogram (mg/kg), and for the 
highest test dose group only, histopathologic examination to include 
testes/ovaries and lungs; an in vivo mouse micronucleus assay 
(intraperitoneal) (OPPTS 870.5395); and an oral developmental toxicity 
study in one species (OPPTS 870.3700). EPA has determined that a fish 
acute toxicity study (OPPTS 850.1075), a daphnid acute toxicity study 
(OPPTS 850.1010), and an algal acute toxicity study (OPPTS 850.5400) 
would help to characterize the environmental effects of these PMN 
substances. The PMN submitter has agreed not to exceed the production 
volume limit without performing these toxicity studies using P-98-1033.
CFR citation: 40 CFR 721.5546.
PMN Number P-99-783
Chemical name: (generic) Chromate(2-), [3-hydroxy-4-[(2-hydroxy-1-
naphthenyl)azo]-7-nitro-1- substituted][N-[7-hydroxy-8-[(2-hydroxy-5-
nitrophenyl)azo]-1-substituted]-, salt.
CAS number: Not available.
Basis for action: The PMN substance will be used for the dyeing of wool 
fiber. Based on structural analogy to anionic dyes, EPA is concerned 
that toxicity to aquatic organisms may occur at a concentration as low 
as 7 part per billion (ppb) of the PMN substance in surface waters. 
Since significant environmental exposure is not expected as described 
in the PMN, EPA has not determined that the proposed manufacturing, 
processing, and use of the PMN substance may present an unreasonable 
risk. EPA has determined, however, that release of the PMN substance to 
surface waters in significant amounts from domestic manufacture may 
cause significant adverse environmental effects. Based on this 
information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii).
Recommended testing: EPA has determined that a daphnid acute toxicity 
study (OPPTS 850.1010 test guideline), and an algal toxicity study 
(OPPTS 850.5400 test guideline) would help to characterize the 
environmental effects of the PMN substance. A stock solution should be 
prepared and its pH adjusted to 7.0 prior to testing. The dilution 
water of the daphnid acute toxicity test should have a hardness of less 
than 180.0 mg/liter(L) as CaCO3 and a total organic carbon 
(TOC) concentration of less than 2.0 mg TOC/L. The green algal growth 
medium should also have a TOC of less than 2.0 mg TOC/L. The daphnid 
test should be done with a flow-through method and measured 
concentrations. The algal toxicity test should be done with the static 
method and measured concentrations.
CFR citation: 40 CFR 721.5288.
PMN Number P-99-817
Chemical name: (generic) Salt of an acrylic acid - acrylamide 
terpolymer
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogy to polyanionic polymers, EPA has 
identified concerns for lung toxicity from respiratory overload if the 
PMN substance is inhaled. Since significant human exposure is unlikely 
when the PMN substance is used as described in the PMN, EPA has not 
determined that the proposed manufacturing, processing, and use of the 
PMN substance may present an unreasonable risk. EPA has determined, 
however, that use of the PMN substance as a solid may result in 
significant human exposure. Based on this information, the PMN 
substance meets the concern criteria at Sec.  721.170(b)(3)(ii).
Recommended testing: EPA has determined that the 90-day inhalation 
toxicity study with a 60-day holding period (OPPTS 870.3465 test 
guideline) would help to characterize the human health effects of the 
PMN substance. Attention should be given to the lungs, including 
histopathology of the lungs (inflamation, epithelial hyperplasia, and 
fibrosis), bronchoalveolar lavage (BAL) analysis for markers of lung 
injury, and lung burden analysis for clearance of the test material 
(EPA-748-R-96-001). The neurotoxicity components and examination of 
organs other than the lungs are not required.
CFR citation: 40 CFR 721.9640.
PMN Number P-99-897
Chemical name: (generic) Substituted benzothiazole-azo-substituted 
benzoquinoline nickel complex.
CAS number: Not available
Basis for action: The PMN substance will be used as a material for 
optical disks. Based on analogy to nickel, EPA is concerned that 
toxicity to aquatic organisms may occur at a concentration as low as 5 
ppb of the PMN substance in surface waters. Since environmental 
releases are not expected as described in the PMN, EPA has not 
determined that the proposed manufacturing, processing, and use of the 
PMN substance may present an unreasonable risk. EPA has determined, 
however, that release of the PMN substance to surface waters may cause 
significant adverse environmental effects. Based on this

[[Page 70160]]

information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline), a daphnid acute toxicity study 
(OPPTS 850.1010 test guideline), and an algal toxicity study (OPPTS 
850.5400 test guideline) would help to characterize the environmental 
effects of the PMN substance.
CFR citation: 40 CFR 721.5340.
PMN Number P-99-920
Chemical name: Poly(oxy-1,2-ethanediyl), alpha-(9Z)-9-
octadecenyl-.omega.-hydroxy-, phosphate, ammonium salt.
CAS number: 58857-49-1
Basis for action: The PMN substance will be used as a dispersing agent 
for pigment pastes. Based on structural analogy to anionic surfactants, 
EPA is concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 8 ppb of the PMN substance in surface waters. 
Since significant environmental releases are not expected as described 
in the PMN, EPA has not determined that the proposed processing, and 
use of the PMN substance may present an unreasonable risk. EPA has 
determined, however, that domestic manufacture may result in release of 
the PMN substance to surface waters which may cause significant adverse 
environmental effects. Based on this information, the PMN substance 
meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline), a daphnid acute toxicity study 
(OPPTS 850.1010 test guideline), and an algal toxicity study (OPPTS 
850.5400 test guideline) would help to characterize the environmental 
effects of the PMN substance. Tests for fish and daphnids should be 
done with a flow through method and measured concentrations. The algal 
test can be done with a static method and measured concentrations. A 
stock solution of PMN substance should be prepared and adjusted to pH 7 
with either HCl or NaOH.
CFR citation: 40 CFR 721.5293.
PMN Number P-99-928
Chemical name: 2-propanol, 1,1',1'-nitrilotris-, compds. with ethanol 
2-[2-(C12-14-alkyloxy) ethoxy] derivs. hydrogen sulfates.
CAS number: 222975-06-6.
Basis for action: The PMN substance will be used as a surfactant in a 
toilet bowl cleaner. Based on structural analogy to anionic 
surfactants, EPA is concerned that toxicity to aquatic organisms from 
the PMN substance may occur at a concentration of 50 ppb in surface 
waters. Since significant environmental releases are not expected, as 
described in the PMN, EPA has not determined that the proposed 
manufacturing, processing, and use of the PMN substance may present an 
unreasonable risk. EPA has determined, however, that other uses of the 
PMN substance could result in releases to surface waters resulting in 
significant adverse environmental effects. Based on this information 
the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline), a daphnid acute toxicity study 
(OPPTS 850.1010 test guideline), and an algal toxicity study (OPPTS 
850.5400 test guideline) would help to characterize the environmental 
effects of the PMN substance. Fish and daphnid tests should be done 
with a flow-through method and measured concentrations. The algal test 
should also be done with measured concentrations of PMN substance.
CFR citation: 40 CFR 721.5358.
PMN Number P-99-951 and P-99-952
Chemical name: (generic) Polyisobutene epoxide.
CAS number: Not available.
Basis for action: The PMN substances will be used as described in the 
PMNs. Based on structural analogy to epoxides, EPA is concerned that 
toxicity to aquatic organisms from the PMN substances may occur at a 
concentration as low as 10 ppb in surface waters. Since significant 
environmental releases are not expected as described in the PMNs, EPA 
has not determined that the proposed manufacturing, processing, and use 
of the PMN substances may present an unreasonable risk. EPA has 
determined, however, that other uses of the PMN substances may result 
in releases that may cause significant adverse environmental effects. 
Based on this information, the PMN substances meet the concern criteria 
at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline), a daphnid acute toxicity study 
(OPPTS 850.1010 test guideline), and an algal toxicity study (OPPTS 
850.5400 test guideline) would help to characterize the environmental 
effects of the PMN substances. The fish and daphnid tests should be 
done using the flow-though method and measured concentrations. The 
algae test should be done using the static method and measured 
concentrations.
CFR citation: 40 CFR 721.2685.
PMN Number P-99-1075
Chemical name: 2-Propenoic acid, 2-methyl-, (octahydro-4,7-methano-1H- 
indene-5,?- diyl)bis(methylene) ester.
CAS number: 43048-08-4.
Basis for action: The PMN substance will be used as a coating agent for 
resin curing. Based on analogy to methacrylates and esters, EPA is 
concerned that toxicity to aquatic organisms from the PMN substance may 
occur at a concentration as low as 5 ppb in surface waters. EPA 
determined that use of the PMN substance as described in the PMN did 
not present an unreasonable risk because the PMN substance is imported 
and would not be released to surface waters. EPA has determined that 
domestic manufacturing and other uses of the PMN substance may result 
in releases to surface waters which exceed the concern concentration. 
Based on this information, the PMN substance meets the concern criteria 
at Sec.  721.170(b)(4)(ii)
Recommended testing: EPA has determined that a fish chronic toxicity 
study (OPPTS 850.1400 test guideline), a daphnid chronic toxicity study 
(OPPTS 850.1300 test guideline), and an algal toxicity study (OPPTS 
850.5400 test guideline) would help to characterize the environmental 
effects of the PMN substance.
CFR citation: 40 CFR 721.8485.
PMN Number P-99-1202
Chemical name: (generic) Sulfonyl azide intermediate.
CAS number: Not available
Basis for action: The PMN substance will be used as a reactive additive 
for polymers. Based on structural analogy to azides, EPA is concerned 
that toxicity to aquatic organisms may occur at a concentration as low 
as 1 ppb of the PMN substance in surface waters. Since environmental 
releases are not expected as described in the PMN, EPA has not 
determined that the proposed manufacturing, processing, and use of the 
PMN substance may present an unreasonable risk. EPA has determined, 
however, that any release of the PMN substance to surface waters may 
cause significant adverse environmental effects. Based on this 
information the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii). Also, based on submitted test data, EPA has 
identified concerns for blood, kidney and lung toxicity from inhalation 
exposure to the PMN substance. Since significant human exposure is 
unlikely when used as described in the PMN, EPA has not determined that 
the proposed manufacturing, processing, and use of the PMN substance 
may present an unreasonable risk. EPA has determined, however, that use 
of the

[[Page 70161]]

PMN substance as a powder may result in significant human exposure. 
Based on this information, the PMN substance meets the concern criteria 
at Sec.  721.170(b)(3)(i).
Recommended testing: EPA has determined that a fish chronic toxicity 
study (OPPTS 850.1400 test guideline), a daphnid chronic toxicity study 
(OPPTS 850.1300 test guideline), and an algal toxicity study (OPPTS 
850.5400 test guideline) would help to characterize the environmental 
effects of the PMN substance. The fish and daphnid tests should use a 
flow-through method and measured concentrations. The algal toxicity 
test should use the static method and measured concentrations. A 90-day 
inhalation toxicity study (OPPTS 870.3465 test guideline) would help to 
characterize the human health effects of the PMN substance.
CFR citation: 40 CFR 721.983.
PMN Number P-99-1288
Chemical name: (generic) Substituted anilino halobenzamide.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogues for anilines and phenols, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 1 ppb of the PMN substance in surface waters. 
Since environmental releases are not expected as described in the PMN, 
EPA has not determined that the proposed manufacturing, processing, and 
use of the PMN substance may present an unreasonable risk. EPA has 
determined, however, that domestic manufacture may result in release of 
the PMN substance to surface waters which may cause significant adverse 
environmental effects. Based on this information, the PMN substance 
meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline), a daphnid acute toxicity study 
(OPPTS 850.1010 test guideline), and an algal toxicity study (OPPTS 
850.5400 test guideline) would help to characterize the environmental 
effects of the PMN substance. The fish and daphnid tests should be 
performed with a flow-through method and measured concentrations. The 
algal test should be done with measured concentrations. A stock 
solution of the PMN substance should be prepared and its pH adjusted to 
pH 7 with either HCl or NaOH.
CFR citation: 40 CFR 721.4096.
PMN Number P-99-1295
Chemical name: (generic) Chlorohydroxyalkyl butyl ether.
CAS number: Not available
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogy to halo alcohols, EPA is concerned 
that toxicity to aquatic organisms may occur at a concentration as low 
as 3 ppb of the PMN substance in surface waters. Since environmental 
releases are not expected as the PMN substance is not released to 
surface waters above 3 ppb, as described in the PMN, EPA has not 
determined that the proposed manufacturing, processing, and use of the 
PMN substance may present an unreasonable risk. EPA has determined, 
however, that other uses of the PMN substance resulting in release to 
surface waters above 3 ppb may cause significant adverse environmental 
effects. Based on this information, the PMN substance meets the concern 
criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline), a daphnid acute toxicity study 
(OPPTS 850.1010 test guideline), and an algal toxicity study (OPPTS 
850.5400 test guideline) would help to characterize the environmental 
effects of the PMN substance. The fish and daphnid tests should be 
performed under flow through conditions with measured concentrations. 
The algal test should be performed under static conditions with 
measured concentrations.
CFR citation: 40 CFR 721.3438.
PMN Number P-99-1304
Chemical name: (generic) Substituted benzenesulfonic acid salt.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogy to anionic surfactants, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 2 ppb of the PMN substance in surface waters. 
Since significant environmental releases are not expected, as described 
in the PMN, EPA has not determined that the proposed manufacturing, 
processing, and use of the PMN substance may present an unreasonable 
risk to the environment. EPA has determined, however, that other uses 
of the PMN substance resulting in release to surface waters in 
significant amounts, may cause significant adverse environmental 
effects. Based on this information the PMN substance meets the concern 
criteria at Sec.  721.170(b)(4)(ii). Also, based on structural 
analogues, EPA has identified concerns for lung effects from inhalation 
exposure to the PMN substance. Since significant human exposure is 
unlikely for the use described in the PMN, EPA has not determined that 
the proposed manufacturing, processing, and use of the PMN substance 
may present an unreasonable risk to human health. EPA has determined, 
however, that other uses of the PMN substance, may result in 
significant human exposure. Based on this information, the PMN 
substance meets the concern criteria at Sec.  721.170(b)(3)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline), a daphnid acute toxicity study 
(OPPTS 850.1010 test guideline), and an algal toxicity study (OPPTS 
850.5400 test guideline) would help to characterize the environmental 
effects of the PMN substance. The fish and daphnid tests should be 
conducted with flow through methods and measured concentrations. The 
algal test should be conducted with static methods and measured 
concentrations. A stock solution should be prepared and its pH adjusted 
to 7.0 with either HCl or NaOH. A 90-day inhalation toxicity study 
(OPPTS 870.3465 test guideline) would help to characterize the human 
health effects of the PMN substance.
CFR citation: 40 CFR 721.1648.
PMN Number P-99-1341
Chemical name: 2-Naphthalenecarboxylic acid, 4,4'-methylenebis [3-
hydroxy-, strontium salt.
CAS number: 235083-90-6.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogy to phenols, anionic surfactants, and 
inorganic metal salts, EPA is concerned that toxicity to aquatic 
organisms may occur at a concentration as low as 3 ppb of the PMN 
substance in surface waters. Since significant environmental exposure 
is not expected as the PMN substance is not released to surface water 
above10 ppb, as described in the PMN, EPA has not determined that the 
proposed manufacturing, processing, and use of the PMN substance may 
present an unreasonable risk. EPA has determined, however, that other 
uses of the PMN substance resulting in release to surface waters above 
10 ppb may cause significant adverse environmental effects. Based on 
this information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline); a daphnid acute toxicity study 
(OPPTS 850.1010 test guideline), an algal toxicity study (OPPTS 
850.5400 test guideline) would help to characterize the environmental 
effects of the PMN substance. All studies should use the

[[Page 70162]]

static method and nominal concentrations.
CFR citation: 40 CFR 721.5253.
PMN Number P-99-1342
Chemical name: 2-Naphthalenecarboxylic acid, 4,4'-methylenebis [3-
hydroxy-, zinc salt
CAS number: 235083-88-2.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogy to phenols, anionic surfactants, and 
inorganic metal salts, EPA is concerned that toxicity to aquatic 
organisms may occur at a concentration as low as 3 ppb of the PMN 
substance in surface waters. Since significant environmental exposure 
is not expected as the PMN substance is not released to surface water 
above 10 ppb, as described in the PMN, EPA has not determined that the 
proposed manufacturing, processing, and use of the PMN substance may 
present an unreasonable risk. EPA has determined, however, that other 
uses of the PMN substance resulting in release to surface waters above 
10 ppb may cause significant adverse environmental effects. Based on 
this information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline), a daphnid acute toxicity study 
(OPPTS 850.1010 test guideline), and an algal toxicity study (OPPTS 
850.5400 test guideline) would help to characterize the environmental 
effects of the PMN substance. All studies should use the static method 
and nominal concentrations.
CFR citation: 40 CFR 721.5252.
PMN Number P-00-7
Chemical name: D-Glucuronic acid, polymer with 6-deoxy-L-mannose and D-
glucose, acetate, calcium magnesium potassium sodium salt.
CAS number: 125005-87-0.
Basis for action: The PMN substance will be used as an oilfield 
drilling fluid, an oilfield spacer fluid, in oilfield cementing, in 
cementitious packaged products, in concrete applications, and in foam 
applications. Based on structural analogues and submitted test data, 
EPA has identified concerns for lung effects from inhalation exposure 
to the PMN substance. Since significant inhalation exposure is unlikely 
when used as described in the PMN, EPA has not determined that the 
proposed manufacturing, processing, and use of the PMN substance may 
present an unreasonable risk. EPA has determined, however, that use of 
the PMN substance other than as described in the PMN may result in 
significant human exposure. Based on this information, the PMN 
substance meets the concern criteria at Sec.  721.170(b)(3)(i) and 
(b)(3)(ii).
Recommended testing: EPA has determined that the 90-day inhalation 
toxicity study with a 60-day holding period (OPPTS 870.3465 test 
guideline) would help to characterize the human health effects of the 
PMN substance. Attention should be given to the lungs, including 
histopathology of the lungs (inflamation, epithelial hyperplasia, and 
fibrosis), (BAL) analysis for markers of lung injury, and lung burden 
analysis for clearance of the test material (EPA-748-R-96-001). The 
neurotoxicity components and examination of organs other than the lungs 
are not required in the 90-day study.
CFR citation: 40 CFR 721.2076.
PMN Number P-00-368
Chemical name: (generic) Benzenesulfonamide, 
alkylphenylsubstitutedphenyl substituted carbonyl-.
CAS number: Not available.
Effective date of section 5(e) consent order: March 28, 2001.
Basis for section 5(e) consent order: The Order was issued under 
section 5(e)(1)(A)(i) and (e)(1)(A)(ii)(I) of TSCA based on a finding 
that the PMN substance may present an unreasonable risk of injury to 
human health and the environment.
Recommended testing: EPA has determined that a subchronic inhalation 
toxicity study (OPPTS 870.3465) would help to characterize the 
potential health effects of the PMN substance. EPA has also determined 
that a fish chronic toxicity study (OPPTS 850.1400) and a daphnid 
chronic toxicity test (OPPTS 850.1300) would help to characterize 
potential environmental effects.
CFR citation: 40 CFR 721.1620.
PMN Number P-00-636
Chemical name: (generic) Alkylated nitroso-phenylenediamine.
CAS number: Not available.
Basis for action: The PMN substance will be used as a polymerization 
inhibitor. Based on test data for the PMN substance and analogy to 
structurally similar compounds, EPA has identified human health 
concerns for systemic effects, reproductive effects, and cancer from 
dermal exposure to the PMN substance. Since significant worker exposure 
is unlikely when the PMN substance is used as described in the PMN, EPA 
has not determined that the proposed manufacturing, processing, and use 
of the PMN substance may present an unreasonable risk. EPA has 
determined, however, that use of the PMN substance without dermal 
protection could result in worker exposures which may cause significant 
adverse human health effects. Based on this information the PMN 
substance meets the concern criteria at Sec.  721.170(b)(3)(i), 
(b)(3)(ii), and (b)(1)(i)(C).
Recommended testing: The Agency has determined that the results of a 2-
generation reproduction/fertility effects study (OPPTS 870.3800 test 
guideline) and a carcinogenicity study (OPPTS 870.4200 test guideline) 
would help to characterize possible human health effects of the PMN 
substance.
CFR citation: 40 CFR 721.5935.
PMN Number P-00-838
Chemical name: (generic) Substituted alkyl sulfonamide.
CAS number: Not available.
Basis for action: The PMN substance will be used for a contained use in 
an article. Based on structural analogy to neutral organic compounds, 
EPA is concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 1 ppb of the PMN substance in surface waters. 
Since significant environmental exposure is not expected as the PMN 
substance is not released to surface waters above 1 ppb, EPA has not 
determined that the proposed processing and use of the PMN substance 
may present an unreasonable risk. EPA has determined, however, that 
releases to surface waters above 1 ppb may cause significant adverse 
environmental effects. Based on this information, the PMN substance 
meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: The Agency has determined that the results of a 
fish chronic toxicity study (OPPTS 850.1400 test guideline) would help 
to characterize possible environmental effects of the PMN substance. 
This test should be conducted with flow-through conditions and measured 
concentrations.
CFR citation: 40 CFR 721.9572.
PMN Number P-00-912
Chemical name: (generic) Epoxy resin containing phosphorus.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. EPA has identified health concerns for carcinogenicity, 
reproductive toxicity in males, and developmental toxicity based on 
structural analogy to epoxides. EPA also identified health and 
environmental concerns because the PMN substance may be persistent, 
bioaccumulative, and potentially toxic based on physical/chemical 
properties of the PMN substance as described in the New Chemical 
Program's Persistent, Bioiaccumulative, and Toxic (PBT) Category (64 FR 
60194, FRL-6907-7, November 4, 1999). Since significant worker and 
environmental exposure is

[[Page 70163]]

unlikely when used as described in the PMN, EPA has not determined that 
the proposed manufacturing, processing, and use of the PMN substance 
may cause significant adverse effects. EPA has determined, however, 
that use of the PMN substance other than as described in the PMN could 
result in exposures which may cause serious chronic effects and 
significant environmental effects. Based on this information, the PMN 
substance meets the concern criteria at Sec.  721.170 (b)(l)(i)(C), 
(b)(3)(ii), and (b)(4)(ii).
Recommended testing: EPA has determined that the results of the tiered 
testing as described in the New Chemical Program's PBT Category would 
help to characterize the PBT properties of the PMN substance. EPA has 
also determined that a fish chronic toxicity study (OPPTS 850.1400 test 
guideline), a daphnid chronic toxicity study (OPPTS 850.1300 test 
guideline), and an algal toxicity study (OPPTS 850.5400 test guideline) 
would help to characterize the environmental effects of the PMN 
substance. The fish and daphnid tests should be conducted with flow-
through methods and measured concentrations The algal test should be 
conducted with static methods and measured concentrations. In addition, 
a 2-year, two-species oral carcinogenicity study (OPPTS 870.4200 test 
guideline) and a 90-day oral subchronic in rats (OPPTS 870.3100 test 
guideline), with attention to pathology of the reproductive organs, 
would help to characterize the health effects of the PMN substance.
CFR citation: 40 CFR 721.2752.
PMN Number P-00-966
Chemical name: (generic) Haloarylalkylketoester.
CAS number: Not available.
Basis for action: The PMN substance will be used as an agricultural 
product intermediate. Toxicity data on structurally similar esters 
indicate that the PMN substance may cause toxicity to aquatic 
organisms. Based on this data, EPA expects toxicity to aquatic 
organisms to occur at a concentration as low as 200 ppb of the PMN 
substance in surface waters. Since environmental releases to surface 
waters are not expected to exceed 200 ppb, EPA has not determined that 
the proposed processing and use of the PMN substance may present an 
unreasonable risk. EPA has determined, however, that if releases to 
surface waters were to exceed a concentration of 200 ppb, the PMN 
substance may cause significant adverse environmental effects. Based on 
this information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii).
Recommended testing: The Agency has determined that an algal toxicity 
test (OPPTS 850.5400 test guideline), an aquatic invertebrate acute 
toxicity test (OPPTS 850.1010 test guideline), and a fish acute 
toxicity test (OPPTS 850.1075 test guideline) would help to 
characterize possible environmental effects of the PMN substance. Ready 
biodegradation testing (OPPTS 835.3110 test guideline) would help to 
characterize possible environmental effects of the PMN substance as 
well. The aquatic toxicity tests should be conducted with flow-through 
conditions and measured concentrations.
CFR citation: 40 CFR 721.3062.
PMN Number P-00-991
Chemical name: Formaldehyde, polymer with (chloromethyl) oxirane and 
phenol, reaction products with 6H-dibenz[c,e][1,2]oxaphosphorin-6-
oxide.
CAS number: 300371-38-4.
Basis for action: The PMN substances will be used in the manufacturing 
of composites. Based on structural analogy to epoxides, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 6 ppb of the PMN substances in surface waters. 
Since significant environmental exposure is not expected, as the PMN 
substances are not released to surface waters above 6 ppb, as described 
in the PMNs, EPA has not determined that the proposed manufacturing, 
processing, and use of the PMN substances may present an unreasonable 
risk. EPA has determined, however, that other uses of the PMN 
substances resulting in release to surface waters above 6 ppb may cause 
significant adverse environmental effects. Based on this information, 
the PMN substances meet the concern criteria at Sec.  
721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline), a daphnid acute toxicity study 
(OPPTS 850.1010 test guideline), and an algal acute toxicity study 
(OPPTS 850.5400 test guideline) would help to characterize the 
environmental effects of the PMN substances.
CFR citation: 40 CFR 721.5560
PMN Number P-00-1055
Chemical name: (generic) Sulfonated-copper phthalocyanine salt of a 
triarylmethane dye
CAS number: Not available.
Basis for action: The PMN substance will be used as a shading additive 
for ink. Based on analogy to cationic dyes, EPA is concerned that 
toxicity to aquatic organisms may occur at a concentration as low as 1 
ppb of the PMN substance in surface waters. Since significant 
environmental exposure is not expected as the PMN substance is not 
released to surface waters above 1 ppb, as described in the PMN, EPA 
has not determined that proposed manufacturing, processing, and use of 
the use of the PMN substance may present an unreasonable risk. EPA has 
determined, however, that other uses of the PMN substance resulting in 
release to surface waters above 1 ppb may cause significant adverse 
environmental effects. Also, based on analogy to triarylmethane 
pigments and dyes, EPA has identified health concerns for mutagenicity 
and cancer effects from inhalation exposure to the PMN substance. Since 
significant inhalation exposure is unlikely when the PMN substance is 
used described in the PMN, EPA has not determined that the proposed 
manufacturing, processing, and use of the PMN substance may present an 
unreasonable risk. EPA has determined, however, that use of the PMN 
substance in the form of a powder may result in significant human 
exposure. Based on this information, the PMN substance meets the 
concern criteria at Sec.  721.170(b)(4)(ii) and (b)(l)(i)(C).
Recommended testing: EPA has determined that a developmental toxicity 
study with two species (rats and mice) by gavage (OPPTS 870.3700 test 
guideline), a 2-generation reproductive and toxicity study (OPPTS 
870.3800 test guideline), an Ames assay/salmonella study (OPPTS 
870.5100 test guideline), a micronucleus assay (OPPTS 870.5395 test 
guideline), and a carcinogenicity study in rats (OPPTS 870.4200 test 
guideline) would help to characterize human health effects. In 
addition, a fish acute toxicity study (OPPTS 850.1075 test guideline), 
a daphnid acute toxicity study (OPPTS 850.1010 test guideline), and an 
algal acute toxicity study (OPPTS 850.5400 test guideline) would help 
to characterize the environmental effects.
CFR citation: 40 CFR 721.9674.
PMN Number P-00-1205
Chemical name: (generic) 6-Methoxy-1H-benz[de]isoquinoline-2 [3H]-dione 
derivative.
CAS number: Not available.
Basis for action: The PMN substance will be used as an intermediate in 
the manufacture of aqueous dyes. Toxicity data on structurally similar 
chemicals indicate that the PMN substance may cause toxicity to aquatic 
organisms. Based on this data, EPA expects toxicity to aquatic 
organisms to occur at a concentration of 30 ppb of the PMN substance in 
surface waters. Since significant environmental exposure is not 
expected as the PMN substance is not released to surface waters above 
30 ppb, EPA has not determined that the

[[Page 70164]]

proposed processing and use of the PMN substance may present an 
unreasonable risk. EPA has determined, however, that other uses of the 
PMN substance resulting in release to surface waters above 10 ppb may 
cause significant adverse environmental effects. Based on this 
information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii).
Recommended testing: The Agency has determined that the results of a 
fish acute toxicity test (OPPTS 850.1075 test guideline) and a fish 
acute toxicity mitigated by humic acid (OPPTS 850.1085 test guideline), 
and an activated sludge sorption/desorption isotherm test (OPPTS 
835.1110 test guideline) would help to characterize environmental 
effects of the PMN substance.
CFR citation: 40 CFR 721.9078.
PMN Number P-00-1220
Chemical name: (generic) Phenol-biphenyl polymer condensate.
CAS number: Not available.
Basis for action: The PMN substance will be used as an electric 
molding. Based on structural analogy to phenols, EPA is concerned that 
toxicity to aquatic organisms may occur at a concentration as low as 1 
ppb of the PMN substance in surface waters. Since significant 
environmental exposure is not expected as the PMN substance is not 
released to surface water, EPA has not determined that the proposed 
manufacturing, processing, and use of the PMN substance may present an 
unreasonable risk. EPA has determined, however, that any release of the 
PMN substance to surface water may cause significant adverse 
environmental effects. Based on this information, the PMN substance 
meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline), a daphnid acute toxicity study 
(OPPTS 850.1010 test guideline), and an algal acute toxicity study 
(OPPTS 850.5400 test guideline) would help to characterize the 
environmental effects of the PMN substance.
CFR citation: 40 CFR 721.5713.
PMN Number P-01-1
Chemical name: (generic) Chloroformate.
CAS number: Not available
Basis for action: The PMN substance will be used as an intermediate. 
Based on analogy to acid halides and neutral organic compounds, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 2 ppb of the PMN substance and 70 ppb of the 
PMN substance's hydrolysis product in surface waters. EPA has not 
determined that the proposed manufacturing, processing, and use of the 
PMN substance may present an unreasonable risk as the PMN substance is 
not released to surface waters above 2 ppb. EPA has determined, 
however, that other uses of the PMN substance resulting in releases to 
surface waters above 2 ppb may cause significant adverse environmental 
effects. Based on this information, the PMN substance meets the concern 
criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a hydrolysis study at 25 
[deg]C and pH 7 (OPPTS 835.2120 test guideline), a ready 
biodegradability study (OPPTS 835.3110 test guideline), a fish acute 
toxicity study (OPPTS 850.1075 test guideline), a daphnid acute 
toxicity study (OPPTS 850.1010 test guideline), and an algal acute 
toxicity study (OPPTS 850.5400 test guideline) would help to 
characterize the environmental effects of the PMN substance.
CFR citation: 40 CFR 721.3835.
PMN Number P-01-7
Chemical name: (generic) Ethylenediaminetetraacetic acid mixed salt.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. EPA has identified concerns for reproductive toxicity in males and 
mutagenicity based on submitted test data, and carcinogenicity based on 
analogy to nitrilotriacetic acid. Since significant worker exposure is 
unlikely when the PMN substance is used as described in the PMN, EPA 
has not determined that the proposed processing and use of the PMN 
substance may present an unreasonable risk. EPA has determined, 
however, that domestic manufacture or use of the PMN substance in a 
powder form may cause serious health effects. Based on this 
information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(3)(i) and (b)(l)(i)(C).
Recommended testing: EPA has determined that a prenatal developmental 
toxicity study by the oral route in two species (OPPTS 870.3700) and a 
carcinogenicity study in rats (OPPTS 870.4200) would help to 
characterize the human health effects of the PMN substance.
CFR citation: 40 CFR 721.2098.
PMN Number P-01-9
Chemical name: (generic) Halogenated arylsilane.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. EPA has identified environmental concerns because the PMN 
substance may be persistent, bioaccumulative, and potentially toxic 
based on physical/chemical properties of the PMN substance as described 
in the New Chemical Program's PBT Category. Also, based on structural 
analogy to neutral organics, EPA expects toxicity to aquatic organisms 
at surface water concentrations as low as 1 ppb. Since significant 
environmental exposure is not expected, as the PMN substance is not 
released to surface waters, as described in the PMN, EPA has not 
determined that the proposed manufacturing, processing, and use of the 
PMN substance may present an unreasonable risk. EPA has determined, 
however, that release to surface water may cause significant adverse 
environmental effects. Based on this information, the PMN substance 
meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that the results of the tiered 
testing as described in the New Chemicals Program's PBT Category would 
help to characterize the PBT properties of the PMN substance. EPA has 
determined that the results of a fish chronic toxicity study (OPPTS 
850.1400), a daphnid chronic toxicity study (OPPTS 850.1300), and an 
algal toxicity study (OPPTS 850.5400) would help to characterize the 
environmental effects of the PMN substance. The fish and daphnid tests 
should be conducted with flow-through methods and measured 
concentrations The algal test should be conducted with static methods 
and measured concentrations.
CFR citation: 40 CFR 721.9506.
PMN Number P-01-22
Chemical name: Propanoic acid, 2-(trimethoxysilyl)-, ethyl ester.
CAS number: 137787-41-8.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogy to alkoxysilanes, EPA is concerned 
that toxicity to aquatic organisms may occur at a concentration as low 
as 10 ppb of the PMN substance in surface waters. Since significant 
environmental exposure is not expected as the PMN substance is not 
released to surface waters above 10 ppb, as described in the PMN, EPA 
has not determined that the proposed manufacturing, processing, and use 
of the PMN substance may present an unreasonable risk. EPA has 
determined, however, that other uses of the PMN substance resulting in 
release to surface waters above 10 ppb may cause significant adverse 
environmental effects. Based on this information, the PMN substance 
meets the concern criteria at Sec.  721.170(b)(4)(ii).

[[Page 70165]]

Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075), a daphnid acute toxicity study (OPPTS 
850.1010), and an algal toxicity study (OPPTS 850.5400) would help to 
characterize the environmental effects of the PMN substance. The fish 
and daphnid tests should be conducted with flow-through conditions and 
measured concentrations. The algae test should be conducted with static 
conditions and measured concentrations.
CFR citation: 40 CFR 721.7290.
PMN Number P-01-69
Chemical name: (generic) Substituted naphthalene hydrazide.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogy to phenols and hydrazines. EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 1 ppb of the PMN substance in surface waters. 
Since environmental releases are not expected as described in the PMN, 
EPA has not determined that the proposed manufacturing, processing and 
use of the PMN substance as described in the PMN may present an 
unreasonable risk. EPA has determined, however, that any release of the 
PMN substance to surface waters may cause significant adverse 
environmental effects. Based on this information, the PMN substance 
meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline), a daphnid acute toxicity study 
(OPPTS 850.1010 test guideline), and an algal toxicity study (OPPTS 
850.5400 test guideline) would help to characterize the environmental 
effects of the PMN substance. The fish and daphnid tests should be 
conducted with the flow-through method and measured concentrations. The 
algae test should be conducted with the static method and measured 
concentrations.
CFR citation: 40 CFR 721.4258.
PMN Number P-01-71
Chemical name: Phenol, 2,2'-[6-(2,4-dibutoxyphenyl)-1,3,5-triazine-2,4-
diyl]bis[5-butoxy-.
CAS number: 208343-47-9.
Basis for action: The PMN substance will be used as an ultraviolet 
absorber for use in photographic emulsions. Based on structural analogy 
to phenols, EPA is concerned that toxicity to aquatic organisms may 
occur at a concentration as low as 1 ppb of the PMN substance in 
surface waters. Since significant environmental exposure is not 
expected, as the PMN substance is not released to surface waters, as 
described in the PMN, EPA has not determined that the proposed 
manufacturing, processing and use of the PMN substance may present an 
unreasonable risk. EPA has determined, however, that any release to 
surface waters water may cause significant adverse environmental 
effects. Based on this information, the PMN substance meets the concern 
criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish chronic toxicity 
study (OPPTS 850.1400 test guideline), and a daphnid chronic toxicity 
study (OPPTS 850.1300 test guideline) would help to characterize the 
environmental effects of the PMN substance. The fish and daphnid 
studies should be conducted with flow-through method and measured 
concentrations.
CFR citation: 40 CFR 721.5718.
PMN Number P-01-77
Chemical name: (generic) Disubstituted benzenedicarboxcylic acid.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. EPA has identified health concerns for developmental toxicity 
based on structural analogy to phthalate esters. Since significant 
worker exposure is unlikely when the PMN substance is used as described 
in the PMN, EPA has not determined that the proposed manufacturing, 
processing, and use of the PMN substance may present an unreasonable 
risk. EPA has determined, however, that use of the PMN substance other 
than as an intermediate could result in exposures which may cause 
serious health effects. Based on this information, the PMN substance 
meets the concern criteria at Sec.  721.170(b)(3)(ii). Also, based on 
structural analogy to esters, EPA is concerned that toxicity to aquatic 
organisms may occur at a concentration as low as 12 ppb of the PMN 
substance in surface waters. Since significant environmental exposure 
is not expected, as the PMN substance is not released to surface 
waters, as described in the PMN, EPA has not determined that the 
proposed manufacturing, processing and use of the PMN substance as 
described in the PMN may present an unreasonable risk. EPA has 
determined, however, that other uses of the PMN substance resulting in 
release to surface water may cause significant adverse environmental 
effects. Based on this information, the PMN substance meets the concern 
criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a Combined Repeated Dose 
with Reproductive/Developmental Toxicity (OPPTS 870.3650) or a 
Reproductive/Development Toxicity Test (OPPTS 870.3550) would help to 
characterize the human health effects of the PMN substance. EPA has 
also determined that a fish acute toxicity study (OPPTS 850.1075), a 
daphnid acute toxicity study (OPPTS 850.1010), and an algal toxicity 
study (OPPTS 850.5400) would help characterize the environmental 
effects of the PMN substance. The fish and daphnid tests should be 
conducted with the flow-through conditions and measured concentrations. 
The algae test should be conducted with the static method and measured 
concentrations.
CFR citation: 40 CFR 721.2060.
PMN Number P-01-85
Chemical name: (generic) Mono esters from 2-propenoic acid.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogy to esters, EPA is concerned that 
toxicity to aquatic organisms may occur at a concentration as low as 1 
ppb of the PMN substance in surface waters. Since significant 
environmental exposure is not expected, as the PMN substance is not 
released to surface waters, as described in the PMN, EPA has not 
determined that the proposed manufacturing, processing and use of the 
PMN substance may present an unreasonable risk. EPA has determined, 
however, that any release to surface waters may cause significant 
adverse environmental effects. Based on this information, the PMN 
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline), a daphnid acute toxicity study 
(OPPTS 850.1010 test guideline), and an algal toxicity study (OPPTS 
850.5400 test guideline) would help to characterize the environmental 
effects of the PMN substance. All tests should be conducted with flow-
through methods and measured concentrations.
CFR citation: 40 CFR 721.8340.
PMN Number P-01-97
Chemical name: (generic) Polyaziridinyl ester of an aliphatic alcohol.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. EPA has identified health concerns for mutagenicity, 
carcinogenicity, male reproductive toxicity, and developmental toxicity 
based on structural analogy to epoxides. Since significant worker 
exposure is unlikely, when used as described in the PMN, EPA has not 
determined that the proposed manufacturing, processing,

[[Page 70166]]

and use of the PMN substance may present an unreasonable risk. EPA has 
determined, however, that use of the PMN substance other than as 
described in the PMN may result in serious health effects. Based on 
this information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(3)(ii) and (b)(l)(i)(C).
Recommended testing: EPA has determined that a 90-day oral subchronic 
toxicity study in rats (OPPTS 870.3100 test guideline), with attention 
to pathology of the reproductive organs, and a carcinogenicity study in 
rats (OPPTS 870.4200 test guideline) would help to characterize the 
human health effects of the PMN substance.
CFR citation: 40 CFR 721.7250.
PMN Number P-01-144
Chemical name: Propanamide, N-(2-hydroxyethyl)-3-methoxy-.
CAS number: 35544-45-7.
Basis for action: The PMN substance will be used as an organic stripper 
additive. EPA has identified health concerns for the solvent properties 
of the PMN substance. Since significant worker exposure is unlikely, 
when the PMN substance is used as described in the PMN, EPA has not 
determined that the proposed manufacturing, processing, and use of the 
PMN substance may present an unreasonable risk. EPA has determined, 
however, that use of the PMN substance other than as described in the 
PMN could result in exposures which may cause serious health effects. 
Based on this information, the PMN substance meets the concern criteria 
at Sec.  721.170(b)(3)(ii).
Recommended testing: EPA has determined that a prenatal developmental 
toxicity study (OPPTS 870.3700 test guideline), a 28-day oral toxicity 
study in rats (OPPTS 870.3050) that includes a neurotoxicity functional 
observational battery (NTIS: PB 91-154617) for all test doses with the 
highest test dose set at 1,000 mg/kg, and for the highest test dose 
group only, histopathologic examination shall be extended to include 
testes/ovaries and lungs, an acute oral toxicity (OPPTS 870.1100 test 
guideline), a mammalian erythrocyte micronucleus test (OPPTS 870.5395 
test guideline), and a salmonella typhimurium reverse mutation assay 
(OPPTS 870.5265 test guideline) would help to characterize the human 
health effects of the PMN substance.
CFR citation: 40 CFR 721.8130.
PMN Number P-01-149
Chemical name: Sulfuric acid, mono-C9-11-alkyl esters, 
sodium salts.
CAS number: 84501-49-5.
Basis for action: The PMN substance will be used as a component in 
surfactant/foaming agent for leather processing. Based on structural 
activity relationship analysis, EPA has identified health concerns for 
internal organ effects. Since significant worker exposure is unlikely, 
when the PMN substance is used as described in the PMN, EPA has not 
determined that the proposed manufacturing, processing, and use of the 
PMN substance may present an unreasonable risk. EPA has determined, 
however, that an increase in production volume may cause serious health 
effects. Based on this information, the PMN substance meets the concern 
criteria at Sec.  721.170(b)(3)(ii).
Recommended testing: EPA has determined that a 90-day subchronic oral 
toxicity study in rodents (OPPTS 870.3100 test guideline) would help to 
characterize the human health effects of the PMN substance.
CFR citation: 40 CFR 721.3130.
PMN Number P-01-152
Chemical name: Benzenamine, 4-methoxy-2-methyl-N-(3-methylphenyl)-.
CAS number: 93072-06-1.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogy to neutral organic compounds, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 5 ppb of the PMN substance in surface waters. 
EPA also identified environmental concerns because the PMN substance 
may be persistent, bioaccumulative, and potentially toxic based on 
physical/chemical properties of the PMN substance as described in the 
New Chemical Program's PBT Category. Since significant environmental 
exposure is not expected as the PMN substance is not released to 
surface water above 5 ppb, as described in the PMN, EPA has not 
determined that the proposed manufacturing, processing, and use of the 
PMN substance may present an unreasonable risk. EPA has determined, 
however, that other uses of the PMN substance resulting in release to 
surface waters above 5 ppb may cause significant adverse environmental 
effects. Based on this information, the PMN substance meets the concern 
criteria at Sec.  721.170 (b)(4)(ii).
Recommended testing: EPA has determined that the results of the tiered 
testing as described in the New Chemicals Program's PBT Category would 
help to characterize the PBT properties of the PMN substance. EPA has 
determined that the results of a fish acute toxicity study (OPPTS 
850.1075 test guideline), a daphnid acute toxicity study (OPPTS 
850.1010 test guideline), and an algal toxicity study (OPPTS 850.5400 
test guideline) would help to characterize the environmental effects of 
the PMN substance.
CFR citation: 40 CFR 721.1070.
PMN Number P-01-170
Chemical name: Acetic acid, [(5-chloro-8-quinolinyl)oxy-]-, 1-
methylhexyl ester.
CAS number: 99607-70-2.
Basis for action: The PMN substance will be used as a seed safener. 
Based on test data, there is concern for liver toxicity and thyroid 
effects. Since significant worker exposure is unlikely, EPA has not 
determined that the proposed processing, and use of the PMN substance 
may present an unreasonable risk. EPA has determined, however, that 
domestic manufacture or use without protective equipment may cause 
serious health effects. Based on this information, the PMN substance 
meets the concern criteria in Sec.  721.170(b)(3)(i).
Recommended testing: The Agency recommends no further toxicity testing 
for hazard assessment of the PMN substance. However, additional 
information on human exposures to the PMN substance would help to 
characterize potential risks.
CFR citation: 40 CFR 721.304.
PMN Number P-01-298
Chemical name: (generic) Substituted propane
CAS number: Not available.
Basis for action: The PMN substance will be used as a polymer additive. 
EPA has identified health concerns for mutagenicity, neurotoxicity, 
developmental toxicity, liver toxicity and kidney toxicity based on 
submitted test data. Since significant worker exposure is unlikely, 
when used as described in the PMN, EPA has not determined that the 
proposed manufacturing, processing, and use of the PMN substance may 
cause significant adverse effects. EPA has determined, however, that 
use of the PMN substance other than as described in the PMN may result 
in serious health effects. Based on this information, the PMN substance 
meets the concern criteria at Sec.  721.170 (b)(3)(i).
Recommended testing: EPA has determined that a prenatal development 
toxicity study by the oral route in two species (OPPTS 870.3100 test 
guideline) would help to characterize the human health effects of the 
PMN substance.
CFR citation: 40 CFR 721.8140.
PMN Number P-01-320
Chemical name: Propane, 1, 1,1,2,2,3,3-heptafluoro-3-methoxy-.
CAS number: 375-03-1.
Basis for action: The PMN substance will be used as heating transfer 
fluid and a refrigerant. EPA has identified

[[Page 70167]]

health concerns for liver and kidney toxicity based on submitted test 
data and cardiac sensitization and developmental toxicity based on 
analog data. Since significant worker exposure is unlikely, when the 
PMN substance is used described in the PMN, EPA has not determined that 
the proposed manufacturing, processing, and use of the PMN substance 
may present an unreasonable risk. EPA has determined, however, that an 
increase in production volume or use of the PMN substance other than as 
described in the PMN could result in serious health effects. Based on 
this information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(i) and (b)(4)(ii).
Recommended testing: EPA has determined that a 90-day subchronic 
inhalation study in rodents (OPPTS 870.3465 test guideline) would help 
to characterize the human health effects of the PMN substance.
CFR citation: 40 CFR 721.8145.
PMN Number P-01-397
Chemical name: (generic) Dihydro quinacridone derivative.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogy to neutral organic compounds, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 2 ppb of the PMN substance in surface waters. 
Since significant environmental exposure is not expected as the PMN 
substance is not released to surface water above 2 ppb, as described in 
the PMN, EPA has not determined that the proposed manufacturing, 
processing, and use of the PMN substance may present an unreasonable 
risk. EPA has determined, however, that an increase in production 
volume or other uses of the PMN substance resulting in releases to 
surface waters above 2 ppb may cause significant adverse environmental 
effects. Based on this information, the PMN substance meets the concern 
criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish chronic toxicity 
study (OPPTS 850.1400 test guideline), a daphnid chronic toxicity study 
(OPPTS 850.1300 test guideline), and an algal toxicity study (OPPTS 
850.5400 test guideline) would help to characterize the environmental 
effects of the PMN substance. The fish and daphnid tests should be 
conducted with flow-through conditions and measured concentrations. The 
algae test should be conducted with static condition and nominal 
concentrations.
CFR citation: 40 CFR 721.9079.
PMN Number P-01-420
Chemical name: (generic) Aromatic acrylate.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogy to acrylates, EPA is concerned that 
toxicity to aquatic organisms may occur at a concentration as low as 3 
ppb of the PMN substance in surface waters. Since significant 
environmental exposure is not expected, as the PMN substance is not 
released to surface waters as described in the PMN, EPA has not 
determined that the proposed manufacturing, processing, and use of the 
PMN substance may present an unreasonable risk. EPA has determined, 
however, that other uses of the PMN substance resulting in release to 
surface waters may cause significant adverse environmental effects. 
Based on this information, the PMN substance meets the concern criteria 
at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline), a daphnid acute toxicity study 
(OPPTS 850.1010 test guideline), and an algal toxicity study (OPPTS 
850.5400 test guideline) would help to characterize the environmental 
effects of the PMN substance.
CFR citation: 40 CFR 721.330.
PMN Number P-01-423
Chemical name: (generic) Substituted benzoic acid.
CAS number: Not available.
Basis for action: The PMN substance will be used as a dye intermediate. 
EPA has identified health concerns for developmental toxicity, 
irritation to lung, skin, eyes, and mucous membranes, blood toxicity, 
male reproductive toxicity, and dermal sensitization based on analogue 
data. Since significant worker exposure is unlikely, when the PMN 
substance is used as described in the PMN, EPA has not determined that 
the proposed processing, and use of the PMN substance may present an 
unreasonable risk. EPA has determined, however, that domestic 
manufacture could result in exposures which may cause serious health 
effects. Based on this information, the PMN substance meets the concern 
criteria at Sec.  721.170(b)(3)(ii).
Recommended testing: EPA has determined that a 90-day subchronic 
inhalation study in rodents (OPPTS 870.3465 test guideline) would help 
to characterize the human health effects of the PMN substance.
CFR citation: 40 CFR 721.1680.
PMN Number P-01-433
Chemical name: (generic) Halogenated alkane.
CAS number: Not available.
Basis for action: The PMN substance will be used as an intermediate. 
Based on analogy to structural analogues, EPA has concerns for 
carcinogenicity and cardiac sensitization. Also, based on analogy to 
neutral organic chemicals, EPA is concerned that toxicity to aquatic 
organisms may occur at a concentration as low as 400 ppb of the PMN 
substance in surface waters. Since significant worker and environmental 
exposure is unlikely, when the PMN substance is used as described in 
the PMN, EPA has not determined that the manufacturing, processing, and 
use of the PMN substance may present an unreasonable risk. EPA 
determined, however, that use of the PMN substance other than as an 
intermediate may result in exposures which may cause serious health 
effects and significant adverse environmental effects. Based on this 
information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(3)(ii) and (b)(4)(ii).
Recommended testing: EPA has determined that a 90-day subchronic 
inhalation study in rodents (OPPTS 870.3465 test guideline) and a 
cardiac sensitization study would help to characterize the human health 
effects of the PMN substance. EPA has also determined that a fish acute 
toxicity study (OPPTS 850.1075 test guideline), a daphnid acute 
toxicity study (OPPTS 850.1010 test guideline), and an algal toxicity 
study (OPPTS 850.5400 test guideline) would help to characterize the 
environmental effects of the PMN substance.
CFR citation: 40 CFR 721.535.
PMN Number P-01-441
Chemical name: (generic) Modified phenolic resin
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. EPA has identified environmental concerns because the PMN 
substance may be persistent, bioaccumulative, and potentially toxic 
based on physical/chemical properties of the PMN substance as described 
in the New Chemical Program's PBT Category. EPA is concerned that 
toxicity to aquatic organisms may occur at a concentration as low as 9 
ppb of the PMN substance in surface waters based on structural analogy 
to phenols. Since environmental exposure is not expected, as the PMN 
substance is not released to surface waters as described in the PMN, 
EPA has not determined that the proposed manufacturing, processing, and 
use of the PMN substance may present an unreasonable risk. EPA has

[[Page 70168]]

determined, however, that other uses of the PMN substance resulting in 
release to surface waters may cause significant adverse environmental 
effects. Based on this information the PMN substance meets the concern 
criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that the results of the tiered 
testing as described in the New Chemical Program's PBT Category would 
help to characterize the PBT properties of the PMN substance. EPA has 
also determined that a fish acute toxicity study (OPPTS 850.1075 test 
guideline), a daphnid acute toxicity study (OPPTS 850.1010 test 
guideline), and an algal toxicity study (OPPTS 850.5400 test guideline) 
would help to characterize the environmental effects of the PMN 
substance.
CFR citation: 40 CFR 721.5905.
PMN Number P-01-459
Chemical name: Chromate(3-), bis[3-[[6-amino-1,4-dihydro-2-[[[4-[(2-
hydroxy-1-naphthalenyl)azo] phenyl]sulfonyl]amino]-4-(oxo-.kappa.O)-5-
pyrimidinyl]azo-.kappa.N1]-4-(hydroxy-.kappa.O)-5-
nitrobenzenesulfonato(3-)]-, trisodium.
CAS number: 178452-72-7
Basis for action: The PMN substance will be used as an acid dye for 
dyeing leather. Based on submitted test data, EPA has identified human 
health concerns for blood, liver, and spleen effects. Since significant 
worker exposure is unlikely, as inhalation exposure is not expected for 
the use described in the PMN, EPA has not determined that the proposed 
manufacturing, processing, and use of the PMN substance may present an 
unreasonable risk. EPA has determined, however, that use of the PMN 
substance in a powder form may cause serious health effects. Based on 
this information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(3)(i).
Recommended testing: EPA has determined that a 90-day inhalation study 
with a 60-day holding period (OPPTS 870.3465 test guideline) would help 
to characterize the human health effects of the PMN substance.
CFR citation: 40 CFR 721.8940.
PMN Number P-01-460
Chemical name: Chromate(3-), bis[3-[[6-amino-1,4-dihydro-2-[[[4-[(2-
hydroxy-1-naphthalenyl)azo] phenyl]sulfonyl]amino]-4-(oxo-.kappa.O)-5-
pyrimidinyl]azo-.kappa.N1]-4-(hydroxy-.kappa.O)-5-
nitrobenzenesulfonato(3-)]-, sodium triethanolamine salts.
CAS number: 327177-98-0.
Basis for action: The PMN substance will be used as an acid dye for 
dyeing leather. Based on submitted test data, EPA has identified human 
health concerns for blood, liver, and spleen effects. Since significant 
worker exposure is unlikely, as inhalation exposure is not expected for 
the use described in the PMN, EPA has not determined that the proposed 
manufacturing, processing, and use of the PMN substance may present an 
unreasonable risk. EPA has determined, however, that use of the PMN 
substance in a powder form may cause serious health effects. Based on 
this information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(3)(i).
Recommended testing: EPA has determined that a 90-day inhalation study 
with a 60-day holding period (OPPTS 870.3465 test guideline) would help 
to characterize the human health effects of the PMN substance.
CFR citation: 40 CFR 721.8950.
PMN Numbers P-00-992 and P-01-471
Chemical name: (generic) Phosphorous modified epoxy resin.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogy to epoxides, EPA is concerned that 
toxicity to aquatic organisms may occur at a concentration as low as 6 
ppb of the PMN substance in surface waters. Since significant 
environmental exposure is not expected as the PMN substance is not 
released to surface water above 6 ppb, as described in the PMN, EPA has 
not determined that the proposed manufacturing, processing, and use of 
the PMN substance may present an unreasonable risk. EPA has determined, 
however, that use of the PMN substance other than as described in the 
PMN could cause releases to surface waters above 6 ppb which may cause 
significant adverse environmental effects. Based on this information, 
the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish chronic toxicity 
study (OPPTS 850.1400 test guideline), a daphnid chronic toxicity study 
(OPPTS 850.1300 test guideline), and an algal toxicity study (OPPTS 
850.5400 test guideline) would help to characterize the environmental 
effects of the PMN substance. The fish and daphnid tests should be 
conducted with flow-through conditions and measured concentrations. The 
algae test should be conducted with static conditions and nominal 
concentrations.
CFR citation: 40 CFR 721.3135.
PMN Number P-01-481
Chemical name: (generic) Polyurethane polymer.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on physical/ chemical properties and submitted test data, 
EPA has identified health concerns for inhalation exposure. Since 
significant inhalation exposure to workers is unlikely, when the PMN 
substance is used as described in the PMN, EPA has not determined that 
the proposed manufacturing, processing, and use of the PMN substance 
may present an unreasonable risk. EPA has determined, however, that use 
of the PMN substance other than that as described in the PMN may cause 
serious health effects. Based on this information, the PMN substance 
meets the concern criteria at Sec.  721.170(b)(3)(i).
Recommended testing: The Agency is not recommending further toxicity 
testing to evaluate potential health effects. However, additional 
information on human exposures to the PMN substance would help to 
characterize potential health risks.
CFR citation: 40 CFR 721.9959.
PMN Number P-01-561
Chemical name: (generic) Modified phenolic resin.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogy to polyphenols, EPA is concerned that 
toxicity to aquatic organisms may occur at a concentration as low as 20 
ppb of the PMN substance in surface waters. Since significant 
environmental exposure is not expected, as the PMN substance is not 
released to surface waters as described in the PMN, EPA has not 
determined that the proposed manufacturing, processing, and use of the 
PMN substance may present an unreasonable risk. EPA has determined, 
however, that any release to surface waters may cause significant 
adverse environmental effects. Based on this information, the PMN 
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline), a daphnid acute toxicity study 
(OPPTS 850.1010 test guideline), and an algal toxicity study (OPPTS 
850.5400 test guideline) would help to characterize the environmental 
effects of the PMN substance.
CFR citation: 40 CFR 721.5908.
PMN Number P-01-573
Chemical name: (generic) Aromatic aldehyde phenolic resin
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogy to phenols, EPA is concerned that 
toxicity to

[[Page 70169]]

aquatic organisms may occur at a concentration of 1 ppb in surface 
waters. Since significant environmental exposure is unlikely, as the 
PMN substance is not released to surface waters, as described in the 
PMN, EPA has not determined that manufacturing, processing, and use of 
the PMN substance may present an unreasonable risk. EPA has determined, 
however, that any release to surface waters may cause significant 
adverse environmental effects. Based on this information, the PMN 
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline), a daphnid acute toxicity study 
(OPPTS 850.1010 test guideline), and an algal toxicity study (OPPTS 
850.5400 test guideline) would help to characterize the environmental 
effects of the PMN substance.
CFR citation: 40 CFR 721.5762.
PMN Number P-01-578
Chemical name: (generic) Alkoxylated alkyl amine.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on analogy to cationic surfactants, EPA is concerned that 
toxicity to aquatic organisms may occur at a concentration as low as 2 
ppb of the PMN substance in surface waters. Since significant 
environmental exposure is unlikely, when the PMN substance is used as 
described in the PMN, EPA has not determined that the proposed 
manufacturing and use of the PMN substance may present an unreasonable 
risk. EPA has determined, however, that use of the PMN substance other 
than as described in the PMN could result in exposures which may cause 
significant adverse environmental effects. Based on this information, 
the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii).
Recommended testing: EPA has determined that an algal toxicity study 
(OPPTS 850.5400 test guideline), a daphnid acute toxicity study (OPPTS 
850.1010 test guideline), and a fish acute toxicity study (OPPTS 
850.1075 test guideline) would help to characterize the environmental 
effects of the PMN substance. All tests should be conducted with static 
methods and nominal concentrations.
CFR citation: 40 CFR 721.647.
PMN Number P-01-646
Chemical name: 1-propanaminium, 3-amino-, N, N, N-trimethyl-N-soya acyl 
derivs., chloride
CAS number: 391232-99-8
Basis for action: The PMN substance will be used as described in the 
PMN. Based on analogy to cationic surfactants, EPA is concerned that 
toxicity to aquatic organisms may occur at a concentration as low as 
200 ppb of the PMN substance in surface waters. Since significant 
environmental exposure is unlikely, when the PMN substance is used as 
described in the PMN, EPA has not determined that the proposed 
manufacturing and use of the PMN substance may present an unreasonable 
risk. EPA has determined, however, that use of the PMN substance other 
than as described in the PMN could result in exposures which may cause 
significant adverse environmental effects. Based on this information, 
the PMN substance meets the concern criteria at Sec.  721.170 
(b)(4)(ii) .
Recommended testing: EPA has determined that an algal toxicity study 
(OPPTS 850.5400 test guideline), a daphnid acute toxicity study OPPTS 
850.1010 test guideline), and a fish acute toxicity study (OPPTS 
850.1075 test guideline) would help to characterize the environmental 
effects of the PMN substance. All tests should be conducted with static 
methods and nominal concentrations.
CFR citation: 40 CFR 721.7270
PMN Number P-01-716
Chemical name: (generic) Polyurea.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. EPA has identified environmental concerns because the PMN 
substance may be persistent, bioaccumulative, and potentially toxic 
based on physical/chemical properties of the PMN substance as described 
in the New Chemical Program's PBT category. EPA is concerned that 
toxicity to aquatic organisms may occur at a concentration as low as 1 
ppb of the PMN substance in surface waters based on submitted test 
data. Since environmental exposure is not expected, as the PMN 
substance is not released to surface waters as described in the PMN, 
EPA has not determined that the proposed manufacturing, processing, and 
use of the PMN substance may present an unreasonable risk. EPA has 
determined, however, that other uses of the PMN substance resulting in 
releases to surface waters may cause significant adverse environmental 
effects. Based on this information, the PMN substance meets the concern 
criteria at Sec.  721.170(b)(4)(i).
Recommended testing: EPA has determined that the results of the tiered 
testing as described in the New Chemical Program's PBT Category would 
help to characterize the PBT properties of the PMN substance. EPA has 
also determined that an algal toxicity study (OPPTS 850.5400 test 
guideline), a fish chronic toxicity study (OPPTS 850.1400 test 
guideline), a daphnid chronic toxicity study (OPPTS 850.1300 test 
guideline), a fish bioaccumulation test (OPPTS 850.1730), and a shake-
flask die-away test (OPPTS 835.3170 test guideline) would help to 
characterize the environmental effects of the PMN substance.
CFR citation: 40 CFR 721.9929.
PMN Number P-01-781
Chemical name: Silane, triethoxy[3-(oxiranylmethoxy)propyl]-
CAS number: 2602-34-8.
Basis for action: The PMN substance will be used as described in the 
PMN. EPA has identified health concerns for carcinogenicity based on 
analogy to epoxides. EPA has concerns also for mutagenicity, 
developmental toxicity, reproductive toxicity, irritation, and 
sensitization based on analogy to trimethoxy silane derivatives. Since 
significant worker exposure is unlikely, when the PMN substance is used 
as described in the PMN, EPA has not determined that the proposed 
manufacturing, processing, and use of the PMN substance may present an 
unreasonable risk. EPA has determined, however, that use of the PMN 
substance other than as described in the PMN may cause serious health 
effects. Based on this information the PMN substance meets the concern 
criteria at Sec.  721.170(b)(1)(i)(C) and (b)(3)(ii) . Also, based on 
structural analogy to epoxides, EPA is concerned that toxicity to 
aquatic organisms may occur at a concentration as low as 10 ppb of the 
PMN substance in surface waters. Since environmental exposure is not 
expected as the PMN substance is not released to surface waters above 
10 ppb, as described in the PMN, EPA has not determined that the 
proposed manufacturing, processing and use of the PMN substance may 
present an unreasonable risk. EPA has determined, however, that 
releases to surface waters above 10 ppb may cause significant adverse 
environmental effects. Based on this information, the PMN substance 
meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a combined chronic 
toxicity/carcinogenicity study (OPPTS 870.4300 test guideline) and a 
90-day subchronic inhalation study in rodents with attention to 
pathology of the reproductive organs (OPPTS 870.3465 test guidelines) 
would help to characterize the health effects of the PMN substance. EPA 
has determined that a fish acute toxicity study (OPPTS 850.1075 test 
guideline), a daphnid acute toxicity study (OPPTS 850.1010 test 
guideline), and an algal toxicity

[[Page 70170]]

study (OPPTS 850.5400 test guideline) would help to characterize the 
environmental effects of the PMN substance. The fish and daphnid tests 
should be conducted with the flow-through conditions and measured 
concentrations. The algae test should be conducted with the static 
method and measured concentrations.
CFR citation: 40 CFR 721.9501.
PMN Number P-01-833
Chemical name: (generic) Polyethyleneamine crosslinked with substituted 
polyethylene glycol.
CAS number: Not available.
Basis for action: The PMN substance will be used as an absorbent 
polymer. Based on toxicity data for other high molecular weight, water 
swellable polymers, EPA has identified potential lung toxicity from 
inhalation exposure. Since significant inhalation exposure is unlikely 
when the PMN substance is used as identified in the PMN, EPA has not 
determined that the proposed manufacturing, processing, and use of the 
PMN substance may present an unreasonable risk. EPA has determined, 
however, that use of the PMN substance other than as described in the 
PMN may lead to inhalation exposure which could cause serious health 
effects. Based on this information, the PMN substance meets the concern 
criteria at Sec.  721.170(b)(3)(ii).
Recommended testing: EPA has determined that a 90-day inhalation 
toxicity study with a 60-day holding period (OPPTS 870.3465 test 
guideline) would help to characterize the human health effects of the 
PMN substance. Attention should be given to the lungs, including 
histopathology of the lungs (inflamation, epithelial hyperplasia, and 
fibrosis), BAL analysis for markers of lung injury, and lung burden 
analysis for clearance of the test material (EPA-748-R-96-001). The 
neurotoxicity components and examination of organs other than the lungs 
are not required.
CFR citation: 40 CFR 721.7255.
PMN Number P-02-17
Chemical name: (generic) Phenyl azo dye.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on the submitted 28-day study, EPA has concerns for effects 
to the testes. Also, based on structural analogy to the azo reduction 
product, EPA has concerns for developmental toxicity, hemolytic anemia, 
kidney toxicity, liver toxicity, spleen toxicity, and irreversible 
ocular phototoxicity. Since significant inhalation exposure to workers 
is unlikely for the use described in the PMN, EPA has not determined 
that manufacturing, processing, and use of the PMN substance as 
described in the PMN may present an unreasonable risk. EPA has 
determined, however, that use of the PMN substance as a solid may cause 
serious health effects. Based on this information, the PMN substance 
meets the concern criteria at Sec.  721.170(b)(3)(i) and (b)(3)(ii).
Recommended testing: EPA has determined that a prenatal developmental 
toxicity study by the oral route in two species (OPPTS 870.3700 test 
guideline) would help to characterize the human health effects of the 
PMN substance.
CFR citation: 40 CFR 721.5917.
PMN Number P-02-90
Chemical name: (generic) Nickel, cobalt mixed metal oxide.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. EPA has identified health concerns for developmental toxicity, 
mutagenicity, carcinogenicity, cardiotoxicity, immunotoxicity, 
neurotoxicity, and allergenicity based on the presence of various metal 
oxides as well as lung effects from exposure to insoluble particles and 
pulmonary carcinogenicity due to the crystalline nature of the PMN 
material. Since significant worker exposure is unlikely when used as 
described in the PMN, EPA has not determined that the proposed 
manufacturing, processing, and use of the PMN substance may cause 
significant adverse effects. EPA has determined, however, that domestic 
manufacture or use of the PMN substance other than as described in the 
PMN may result in serious health effects. Based on this information, 
the PMN substance meets the concern criteria at Sec.  
721.170(b)(3)(ii).
Recommended testing: EPA has determined that a 90-day subchronic 
inhalation toxicity study in rat (OPPTS 870.3465 test guideline) would 
help to characterize the human health effects of the PMN substance.
CFR citation: 40 CFR 721.5315.
PMN Number P-02-207
Chemical name: Piperdinium, 1,1-dimethyl-, chloride.
CAS number: 24307-26-4.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on submitted test data, EPA has identified health concerns 
for neurotoxicity and chronic toxic effects for the PMN substance. 
Since significant worker exposure is unlikely when used as described in 
the PMN, EPA has not determined that the proposed manufacturing, 
processing, and use of the PMN substance may cause significant adverse 
effects. EPA has determined, however, that use of the PMN substance 
other than as described in the PMN may result in serious health 
effects. Also, based on structural analogy to cationic surfactants, EPA 
is concerned that toxicity to aquatic organisms may occur at surface 
water concentrations as low as 300 ppb of the PMN substance in surface 
waters. Since environmental releases are not expected as described in 
the PMN, EPA has not determined that the proposed manufacturing, 
processing, and use of the PMN substance may present an unreasonable 
risk. EPA has determined, however, that release of the PMN substance to 
surface water may cause significant adverse environmental effects. 
Based on this information, the PMN substance meets the concern criteria 
at Sec.  721.170(b)(3)(i), and (b)(4)(ii).
Recommended testing: EPA has determined that information on potential 
human and environmental exposures would help to characterize the 
potential health and environmental risks of the PMN substance.
CFR citation: 40 CFR 721.6167.
PMN Number P-02-262
Chemical name: (generic) Substituted benzophenone.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on analogy to benzophenones, EPA has identified health 
concerns for neurotoxicity and liver toxicity. Since significant worker 
exposure is unlikely when the PMN substance is used as described in the 
PMN, EPA has not determined that the proposed processing, and use of 
the PMN substance may present an unreasonable risk. EPA has determined, 
however, that domestic manufacture of the PMN substance could result in 
exposures which may cause serious health effects. Based on this 
information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(3)(ii). Also, based on structural analogy to neutral organic 
chemicals, EPA is concerned that toxicity to aquatic organisms may 
occur at a concentration as low as 20 ppb of the PMN substance in 
surface waters. Since environmental releases are not expected as 
described in the PMN, EPA has not determined that the proposed 
manufacturing, processing and use of the PMN substance may present an 
unreasonable risk. EPA has determined, however, that any release of the 
PMN substance to surface water may cause significant adverse 
environmental effects. Based on this information, the PMN substance 
meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a 90-day oral

[[Page 70171]]

subchronic study in rats (OPPTS 870.3465 test guideline) would help 
characterize the human health effects of the PMN substance. EPA has 
also determined that a fish acute toxicity study (OPPTS 850.1075 test 
guideline), a daphnid acute toxicity study (OPPTS 850.1010 test 
guideline), and an algal acute toxicity study (OPPTS 850.5400 test 
guideline) would help to characterize the environmental effects of the 
PMN substance.
CFR citation: 40 CFR 721.1747.

IV. Objectives and Rationale of the Rule

    During review of the PMNs submitted for the chemical substances 
that are subject to this SNUR, EPA concluded that for 5 of the 65 
chemical substances, regulation was warranted under section 5(e) of 
TSCA, pending the development of information sufficient to make 
reasoned evaluations of the health or environmental effects of the 
chemical substances. The basis for such findings is outlined in Unit 
III. Based on these findings, TSCA section 5(e) consent orders 
requiring the use of appropriate exposure controls were negotiated with 
the PMN submitters; the SNUR provisions for these chemical substances 
listed in this document are consistent with the provisions of the TSCA 
section 5(e) consent orders.
    In the other 60 cases for which the proposed uses are not regulated 
under a TSCA section 5(e) consent order, EPA determined that one or 
more of the criteria of concern established at 40 CFR 721.170 were met.
    EPA is issuing this SNUR for specific chemical substances which 
have undergone premanufacture review to ensure that:
    1. EPA will receive notice of any company's intent to manufacture, 
import, or process a listed chemical substance for a significant new 
use before that activity begins.
    2. EPA will have an opportunity to review and evaluate data 
submitted in a SNUR notice before the notice submitter begins 
manufacturing, importing, or processing a listed chemical substance for 
a significant new use.
    3. When necessary, to prevent unreasonable risks, EPA will be able 
to regulate prospective manufacturers, importers, or processors of a 
listed chemical substance before a significant new use of that chemical 
substance occurs.
    4. All manufacturers, importers, and processors of the same 
chemical substance which is subject to a TSCA section 5(e) consent 
order are subject to similar requirements.
    Issuance of a SNUR for a chemical substance does not signify that 
the chemical substance is listed on the TSCA Inventory. Manufacturers, 
importers, and processors are responsible for ensuring that a new 
chemical substance subject to a final SNUR is listed on the TSCA 
Inventory.

V. Direct Final Procedures

    EPA is issuing these SNURs as a direct final rule, as described in 
40 CFR 721.160(c)(3) and 721.170(d)(4). In accordance with 40 CFR 
721.160(c)(3)(ii), this rule will be effective February 17, 2004, 
unless EPA receives a written notice by January 16, 2004, of adverse or 
critical comments, or notice of intent to submit adverse or critical 
comments on EPA's action. If EPA receives such a notice, EPA will 
publish a document to withdraw the direct final SNUR for the specific 
chemical substance to which the adverse or critical comments apply. EPA 
will then propose a SNUR for the specific chemical substance providing 
a 30-day comment period.
    This action establishes SNURs for a number of chemical substances. 
Any person who submits adverse or critical comments or notice of intent 
to submit adverse or critical comments, must identify the chemical 
substance and the new use to which it applies. EPA will not withdraw a 
SNUR for a chemical substance not identified in a notice.

VI. Test Data and Other Information

    EPA recognizes that TSCA section 5 does not require developing any 
particular test data before submission of a SNUN. Persons are required 
only to submit test data in their possession or control and to describe 
any other data known to or reasonably ascertainable by them. In cases 
where a TSCA section 5(e) consent order requires or recommends certain 
testing, Unit III. lists those recommended tests.
    However, EPA has established production limits in the TSCA section 
5(e) consent orders for several of the chemical substances regulated 
under this rule, in view of the lack of data on the potential health 
and environmental risks that may be posed by the significant new uses 
or increased exposure to the chemical substances. These production 
limits cannot be exceeded unless the PMN submitter first submits the 
results of toxicity tests that would permit a reasoned evaluation of 
the potential risks posed by these chemical substances. Under recent 
consent orders, each PMN submitter is required to submit each study at 
least 14 weeks (earlier consent orders required submissions at least 12 
weeks) before reaching the specified production limit. Listings of the 
tests specified in the TSCA section 5(e) consent orders are included in 
Unit III. The SNURs contain the same production volume limits as the 
consent orders. Exceeding these production limits is defined as a 
significant new use.
    The recommended studies may not be the only means of addressing the 
potential risks of the chemical substance. However, SNUNs submitted for 
significant new uses without any test data may increase the likelihood 
that EPA will take action under TSCA section 5(e), particularly if 
satisfactory test results have not been obtained from a prior 
submitter. EPA recommends that potential SNUN submitters contact EPA 
early enough so that they will be able to conduct the appropriate 
tests.
    SNUN submitters should be aware that EPA will be better able to 
evaluate SNUNs which provide detailed information on:
    1. Human exposure and environmental release that may result from 
the significant new use of the chemical substances.
    2. Potential benefits of the chemical substances.
    3. Information on risks posed by the chemical substances compared 
to risks posed by potential substitutes.

VII. Procedural Determinations

    EPA is establishing through this rule some significant new uses 
which have been claimed as CBI subject to Agency confidentiality 
regulations at 40 CFR part 2. EPA is required to keep this information 
confidential to protect the CBI of the original PMN submitter. EPA 
promulgated a procedure to deal with the situation where a specific 
significant new use is CBI. This procedure appears in 40 CFR 
721.1725(b)(1) and is similar to that in Sec.  721.11 for situations 
where the chemical identity of the chemical substance subject to a SNUR 
is CBI. This procedure is cross-referenced in each of these SNURs.
    A manufacturer or importer may request EPA to determine whether a 
proposed use would be a significant new use under this rule. Under the 
procedure in Sec.  721.1725(b)(1), a manufacturer or importer must show 
that it has a bona fide intent to manufacture or import the chemical 
substance and must identify the specific use for which it intends to 
manufacture or import the chemical substance. If EPA concludes that the 
person has shown a bona fide intent to manufacture or import the 
chemical substance, EPA will tell the person whether the use identified 
in the bona fide submission would be a significant new use under the 
rule. Since most of the chemical identities of the chemical substances

[[Page 70172]]

subject to these SNURs are also CBI, manufacturers and processors can 
combine the bona fide submission under the procedure in Sec.  
721.1725(b)(1) with that under Sec.  721.11 into a single step.
    If a manufacturer or importer is told that the production volume 
identified in the bona fide submission would not be a significant new 
use, i.e., it is below the level that would be a significant new use, 
that person can manufacture or import the chemical substance as long as 
the aggregate amount does not exceed that identified in the bona fide 
submission to EPA. If the person later intends to exceed that volume, a 
new bona fide submission would be necessary to determine whether that 
higher volume would be a significant new use. EPA is considering 
whether to adopt a special procedure for use when CBI production volume 
is designated as a significant new use. Under such a procedure, a 
person showing a bona fide intent to manufacture or import the chemical 
substance, under the procedure described in Sec.  721.11, would 
automatically be informed of the production volume that would be a 
significant new use. Thus, the person would not have to make multiple 
bona fide submissions to EPA for the same chemical substance to remain 
in compliance with the SNUR, as could be the case under the procedures 
in Sec.  721.1725(b)(1).

VIII. Applicability of Rule to Uses Occurring Before Effective Date of 
the Final Rule

    To establish a significant "new" use, EPA must determine that the 
use is not ongoing. The chemical substances subject to this rule have 
recently undergone premanufacture review. TSCA section 5(e) consent 
orders have been issued for 5 chemical substances and notice submitters 
are prohibited by the TSCA section 5(e) consent orders from undertaking 
activities which EPA is designating as significant new uses. In cases 
where EPA has not received an NOC and the chemical substance has not 
been added to the TSCA Inventory, no other person may commence such 
activities without first submitting a PMN. For chemical substances for 
which an NOC has not been submitted at this time, EPA has concluded 
that the uses are not ongoing. However, EPA recognizes in cases when 
chemical substances identified in this SNUR are added to the Inventory 
prior to the effective date of the rule, the chemical substances may be 
manufactured, imported, or processed by other persons for a significant 
new use as defined in this rule before the effective date of the rule. 
However, 45 of the 65 chemical substances contained in this rule have 
CBI chemical identities, and since EPA has received a limited number of 
post-PMN bona fide submissions, the Agency believes that it is highly 
unlikely that any of the significant new uses described in the 
following regulatory text are ongoing.
    As discussed in the Federal Register of April 24, 1990, EPA has 
decided that the intent of section 5(a)(1)(B) of TSCA is best served by 
designating a use as a significant new use as of the date of 
publication rather than as of the effective date of the rule. Thus, 
persons who begin commercial manufacture, import, or processing of the 
chemical substances regulated through this SNUR will have to cease any 
such activity before the effective date of this rule. To resume their 
activities, these persons would have to comply with all applicable SNUR 
notice requirements and wait until the notice review period, including 
all extensions, expires.
    EPA has promulgated provisions to allow persons to comply with this 
SNUR before the effective date. If a person were to meet the conditions 
of advance compliance under Sec.  721.45(h), the person would be 
considered to have met the requirements of the final SNUR for those 
activities. If persons who begin commercial manufacture, import, or 
processing of the chemical substance between publication and the 
effective date of the SNUR do not meet the conditions of advance 
compliance, they must cease that activity before the effective date of 
the rule. To resume their activities, these persons would have to 
comply with all applicable SNUR notice requirements and wait until the 
notice review period, including all extensions, expires.

IX. Economic Analysis

    EPA has evaluated the potential costs of establishing SNUN 
requirements for potential manufacturers, importers, and processors of 
the chemical substances subject to this rule. EPA's complete economic 
analysis is available in the public docket.

X. Statutory and Executive Order Reviews

1. Executive Order 12866: Regulatory Planning and Review

    Under Executive Order 12866, entitled Regulatory Planning and 
Review (58 FR 51735, October 4, 1993), the Office of Management and 
Budget (OMB) has determined that proposed or final SNURs are not a 
"significant regulatory action" subject to review by OMB, because 
they do not meet the criteria in section 3(f) of the Executive order.

2. Paperwork Reduction Act

    According to the Paperwork Reduction Act (PRA), 44 U.S.C. 3501 et 
seq., an Agency may not conduct or sponsor, and a person is not 
required to respond to a collection of information that requires OMB 
approval under the PRA, unless it has been approved by OMB and displays 
a currently valid OMB control number. The OMB control numbers for EPA's 
regulations in title 40 of the CFR, after appearing in the Federal 
Register, listed in 40 CFR part 9, and included on the related 
collection instrument or form, if applicable.
    The information collection requirements related to this action have 
already been approved by OMB pursuant to the PRA under OMB control 
number 2070-0012 (EPA ICR No. 574). This action does not impose any 
burden requiring additional OMB approval. If an entity were to submit a 
SNUN to the Agency, the annual burden is estimated to average between 
30 and 170 hours per response. This burden estimate includes the time 
needed to review instructions, search existing data sources, gather and 
maintain the data needed, and complete, review, and submit the required 
SNUN.
    Send any comments about the accuracy of the burden estimate, and 
any suggested methods for minimizing respondent burden, including 
through the use of automated collection techniques, to the Director, 
Collection Strategies Division, Office of Environmental Information 
(2822T), Environmental Protection Agency, 1200 Pennsylvania Ave., NW., 
Washington, DC 20460-0001. Please remember to include the OMB control 
number in any correspondence, but do not submit any completed forms to 
this address.

3. Regulatory Flexibility Act

    Pursuant to section 605(b) of the Regulatory Flexibility Act (RFA) 
(5 U.S.C. 601 et seq.), the Agency hereby certifies that promulgation 
of this SNUR will not have a significant adverse economic impact on a 
substantial number of small entities. The rationale supporting this 
conclusion is as follows. A SNUR applies to any person (including small 
or large entities) who intends to engage in any activity described in 
the rule as a "significant new use." By definition of the word 
"new," and based on all information currently available to EPA, it 
appears that no small or large entities presently engage in such 
activity. Since a SNUR only requires that any person who intends to 
engage in such activity in the

[[Page 70173]]

future must first notify EPA by submitting a SNUN, no economic impact 
will even occur until someone decides to engage in those activities. 
Although some small entities may decide to conduct such activities in 
the future, EPA cannot presently determine how many, if any, there may 
be. However, EPA's experience to date is that, in response to the 
promulgation of over 1,000 SNURs, the Agency receives on average only 
10 notices per year. Of those SNUNs submitted, none appear to be from 
small entities in response to any SNUR. In addition, the estimated 
reporting cost for submission of a SNUN (see Unit IX.), are minimal 
regardless of the size of the firm. Therefore, EPA believes that the 
potential economic impact of complying with this SNUR are not expected 
to be significant or adversely impact a substantial number of small 
entities. In a SNUR that published on June 2, 1997 (62 FR 29684) (FRL-
5597-1), the Agency presented it's general determination that proposed 
and final SNURs are not expected to have a significant economic impact 
on a substantial number of small entities, which was provided to the 
Chief Counsel for Advocacy of the Small Business Administration.

4. Unfunded Mandates Reform Act

    Based on EPA's experience with proposing and finalizing SNURs, 
State, local, and Tribal governments have not been impacted by these 
rulemakings, and EPA does not have any reasons to believe that any 
State, local, or Tribal government will be impacted by this rulemaking. 
As such, EPA has determined that this regulatory action does not impose 
any enforceable duty, contain any unfunded mandate, or otherwise have 
any affect on small governments subject to the requirements of sections 
202, 203, 204, or 205 of the Unfunded Mandates Reform Act of 1995 
(UMRA) (Public Law 104-4).

5. Executive Order 13132: Federalism

    This action will not have a substantial direct effect on States, on 
the relationship between the national government and the States, or on 
the distribution of power and responsibilities among the various levels 
of government, as specified in Executive Order 13132, entitled 
Federalism (64 FR 43255, August 10, 1999).

6. Executive Order 13175: Consultation and Coordination with Indian 
Tribal Governments

    This rule does not have Tribal implications because it is not 
expected to have substantial direct effects on Indian Tribes. This does 
not significantly or uniquely affect the communities of Indian Tribal 
governments, nor does it involve or impose any requirements that affect 
Indian Tribes. Accordingly, the requirements of Executive Order 13175, 
entitled Consultation and Coordination with Indian Tribal Governments 
(65 FR 67249, November 6, 2000), do not apply to this rule.

7. Executive Order 13045: Protection of Children from Environmental 
Health Risks and Safety Risks

    This action is not subject to Executive Order 13045, entitled 
Protection of Children from Environmental Health Risks and Safety Risks 
(62 FR 19885, April 23, 1997), because this is not an economically 
significant regulatory action as defined by Executive Order 12866, and 
this action does not address environmental health or safety risks 
disproportionately affecting children.

8. Executive Order 13211: Actions that Significantly Affect Energy 
Supply, Distribution, or Use

    This rule is not subject to Executive Order 13211, entitled Actions 
Concerning Regulations That Significantly Affect Energy Supply, 
Distribution, or Use (66 FR 28355, May 22, 2001), because this action 
is not expected to affect energy supply, distribution, or use.

9. National Technology Transfer Advancement Act

    In addition, since this action does not involve any technical 
standards, section 12(d) of the National Technology Transfer and 
Advancement Act of 1995 (NTTAA), Public Law 104-113, section 12(d) (15 
U.S.C. 272 note), does not apply to this action.

10. Executive Order 12898: Federal Actions to Address Environmental 
Justice in Minority Populations and Low-Income Populations

    This action does not entail special considerations of environmental 
justice related issues as delineated by Executive Order 12898, entitled 
Federal Actions to Address Environmental Justice in Minority 
Populations and Low-Income Populations (59 FR 7629, February 16, 1994).

11. Executive Order 12630: Governmental Actions and Interference With 
Constitutionally Protected Property Rights (Takings)

    EPA has complied with Executive Order 12630, entitled Governmental 
Actions and Interference with Constitutionally Protected Property 
Rights (53 FR 8859, March 15, 1988), by examining the takings 
implications of this rule in accordance with the "Attorney General's 
Supplemental Guidelines for the Evaluation of Risk and Avoidance of 
Unanticipated Takings" issued under the Executive order.

12. Executive Order 12988: Civil Justice Reform

    In issuing this rule, EPA has taken the necessary steps to 
eliminate drafting errors and ambiguity, minimize potential litigation, 
and provide a clear legal standard for affected conduct, as required by 
section 3 of Executive Order 12988, entitled Civil Justice Reform (61 
FR 4729, February 7, 1996).

13. Congressional Review Act

    The Congressional Review Act, 5 U.S.C. 801 et seq., as added by the 
Small Business Regulatory Enforcement Fairness Act of 1996, generally 
provides that before a final rule may take effect, the Agency 
promulgating it must submit a final rule report, which includes a copy 
of the final rule, to each House of the Congress and to the Comptroller 
General of the United States. EPA will submit a report containing this 
final rule and other required information to the U.S. Senate, the U.S. 
House of Representatives, and the Comptroller General of the United 
States prior to publication of the final rule in the Federal Register. 
This final rule is not a "major rule" as defined by 5 U.S.C. 804(2).

List of Subjects in 40 CFR Part 721

    Environmental protection, Chemicals, Hazardous substances, 
Reporting and recordkeeping requirements.


    Dated: December 7, 2003.
Charles M. Auer,
Director, Office of Pollution Prevention and Toxics.


0
Therefore, 40 CFR part 721 is amended as follows:

PART 721--[AMENDED]

0
1. The authority citation for part 721 continues to read as follows:

    Authority: 15 U.S.C. 2604, 2607, and 2625(c).

0
2. By adding new Sec.  721.304 to subpart E to read as follows


Sec.  721.304  Acetic acid, [(5-chloro-8-quinolinyl)oxy-], 1-methyl 
hexyl ester.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as acetic acid, [(5-
chloro-8-quinolinyl)oxy-]-, 1-methylhexyl ester (PMN P-01-170;

[[Page 70174]]

CAS No. 99607-70-2) is subject to reporting under this section for the 
significant new use described in paragraph (a)(1) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(3), (a)(4), and (a)(5)(iv).
    (ii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), (d), (e), and, (i) are applicable to 
manufacturers, importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

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3. By adding new Sec.  721.330 to subpart E to read as follows:


Sec.  721.330  Aromatic acrylate (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as an 
aromatic acrylate (PMN P-01-420) is subject to reporting under this 
section for the significant new use described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified Sec.  721.90(a)(1), 
(b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

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4. By adding new Sec.  721.535 to subpart E to read as follows:


Sec.  721.535  Halogenated alkane (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
halogenated alkane (PMN P-01-433) is subject to reporting under this 
section for the significant new use described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(g).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

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5. By adding new Sec.  721.647 to subpart E to read as follows:


Sec.  721.647  Alkoxylated alkyl amine (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as an 
alkoxylated alkyl amine (PMN P-01-578) is subject to reporting under 
this section for the significant new use described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to this section.

0
6. By adding new Sec.  721.983 to subpart E to read as follows:


Sec.  721.983  Sulfonyl azide intermediate (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
sulfonyl azide intermediate (PMN P-99-1202) is subject to reporting 
under this section for the significant new use described in paragraph 
(a)(1) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (ii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f), (v)(1), and (x)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), (i), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

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7. By adding new Sec.  721.1070 to subpart E to read as follows:


Sec.  721.1070  Benzenamine, 4-methoxy-2-methyl-N-(3-methylphenyl).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
benzenamine, 4-methoxy-2-methyl-N-(3-methylphenyl) (PMN P-01-152; CAS 
No. 93072-06-1) is subject to reporting under this section for the 
significant new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=5).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

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8. By adding new Sec.  721.1620 to subpart E to read as follows:


Sec.  721.1620  Benzenesulfonamide, alkylphenyl substituted phenyl 
substituted carbonyl- (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
benzenesulfonamide alkylphenyl substituted phenyl substituted carbonyl- 
(PMN P-00-368) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.

[[Page 70175]]

    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(4), (a)(5)(iii), (a)(5)(iv), (a)(5)(v), (a)(5)(vi), 
(a)(5)(vii), (a)(6)(i), (b) (concentration set at 1.0%), and (c). As an 
alternative to the respiratory requirements listed here, a 
manufacturer, importer, or processor may choose to follow the new 
chemical exposure limit (NCEL) provisions listed in the TSCA section 
5(e) consent order for this chemical substance.
    (ii) Hazard communication program. Requirements as specified in 
Sec.  721,72(a), (b), (c), (d), (e) (concentration set at 1.0%), (f), 
(g)(1)(iv), (g)(2)(ii), (g)(2)(iv), (g)(3)(ii), (g)(4)(i), and (g)(5).
    (iii) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=30).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), (d), (f), (g), (h), and (k) are applicable to 
manufacturers, importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

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9. By adding new Sec.  721.1648 to subpart E to read as follows:


Sec.  721.1648  Substituted benzenesulfonic acid salt (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substituted benzenesulfonic acid (PMN P-99-1304) is subject to 
reporting under this section for the significant new use described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of 721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to this section.

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10. By adding new Sec.  721.1680 to subpart E to read as follows:


Sec.  721.1680  Substituted benzoic acid (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substituted benzoic acid (PMN P-01-423) is subject to reporting under 
this section for the significant new use described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
11. By adding new Sec.  721.1747 to subpart E to read as follows:


Sec.  721.1747  Substituted benzophenone (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
substituted benzophenone (PMN P-02-262) is subject to reporting under 
this section for the significant new use described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f).
    (ii) Release to water. Requirement as specified Sec.  721.90(b)(1) 
and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), (i), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

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12. By adding new Sec.  721.2060 to subpart E to read as follows:


Sec.  721.2060  Disubstituted benzenedicarboxylic acid (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
disubstituted benzenedicarboxylic acid (PMN P-01-77) is subject to 
reporting under this section for the significant new use described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(g).
    (ii) Release to water. Requirements as specified Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), (i), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

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13. By adding new Sec.  721.2076 to subpart E to read as follows:


Sec.  721.2076  D-Glucuronic acid, polymer with 6-deoxy-L-mannose and 
D-glucose, acetate, calcium magnesium potassium sodium salt.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as D-Glucuronic acid, 
polymer with 6-deoxy-L-mannose and D-glucose, acetate, calcium 
magnesium potassium sodium salt (PMN P-00-7; CAS No.125005-87-0) is 
subject to reporting under this section for the significant new use 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j) (oilfield drilling fluid, oilfield 
spacer fluid, oilfield cementing, cementitious packaged products, 
concrete applications, and foam applications).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.

[[Page 70176]]

    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

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14. By adding new Sec.  721.2098 to subpart E to read as follows:


Sec.  721.2098  Aliphatic polycarboxylic acid metal salt (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as an 
aliphatic polycarboxylic acid metal salt (PMN P-01-7) is subject to 
reporting under this section for the significant new use described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(v)(1), (x)(1), and (f).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

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15. By adding new Sec.  721.2685 to subpart E to read as follows:


Sec.  721.2685  Polyisobutene epoxide (generic).

    (a) Chemical substances and significant new uses subject to 
reporting. (1) The chemical substances identified generically as 
polyisobutene epoxide (PMNs P-99-951 and P-99-952) are subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to this section.

0
16. By adding new Sec.  721.2752 to subpart E to read as follows:


Sec.  721.2752  Epoxy resin containing phosphorus (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as an 
epoxy resin containing phosphorus (PMN P-00-912) is subject to 
reporting under this section for the significant new use described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.575(b)(1) apply to this section.

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17. By adding new Sec.  721.3062 to subpart E to read as follows:


Sec.  721.3062  Haloarylalkylketoester (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
haloarylalkylketoester. (PMN P-00-966) is subject to reporting under 
this section for the significant new use described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=200).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
18. By adding new Sec.  721.3110 to subpart E to read as follows:


Sec.  721.3110  Polycarboxylic acid ester (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
polycarboxylic acid ester (PMN P-97-1108) is subject to reporting under 
this section for the significant new use described in paragraph (a)(1) 
of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or evocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

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19. By adding new Sec.  721.3130 to subpart E to read as follows:


Sec.  721.3130  Sulfuric acid, mono-C9-11-alkyl esters, 
sodium salts.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as sulfuric acid, 
mono-C9-11-alkyl esters, sodium salts (PMN P-01-149; CAS No. 
84501-49-5) is subject to reporting under this section for the 
significant new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(s) (5,000 kilogram (kg)).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

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20. By adding new Sec.  721. 3135 to subpart E to read as follows:

[[Page 70177]]

Sec.  721.3135  Phosphorous modified epoxy resin (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
phosphorous modified epoxy resin (PMNs P-00-992 and P-01-471) is 
subject to reporting under this section for the significant new use 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified Sec.  721.90(a)(4), 
(b)(4), and (c)(4) (N=6).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

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21. By adding new Sec.  721.3438 to subpart E to read as follows:


Sec.  721.3438  Chlorohydroxyalkyl butyl ether (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
chlorohydroxyalkyl butyl ether (PMN P-99-1295) is subject to reporting 
under this section for the significant new use described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=3).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

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22. By adding new Sec.  721.3835 to subpart E to read as follows:


Sec.  721.3835  Chloroformate (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
chloroformate (PMN P-01-1) is subject to reporting under this section 
for the significant new use described in paragraph (a)(2) of this 
section.
    (2) The significant new uses are:
    (i) Releases to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=2).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
23. By adding new Sec.  721.4096 to subpart E to read as follows:


Sec.  721.4096  Substituted anilino halobenzamide (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substituted anilino halobenzamide (PMN P-99-1288) is subject to 
reporting under this section for the significant new use described in 
paragraph (a)(1) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
24. By adding new Sec.  721.4258 to subpart E to read as follows:


Sec.  721.4258  Substituted naphthalene hydrazide (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substituted naphthalene hydrazide (PMN P-01-69) is subject to reporting 
under this section for the significant new use described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirement as specified Sec.  721.90(a)(1), 
(b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
25. By adding new Sec.  721.5252 to subpart E to read as follows:


Sec.  721.5252  2-Naphthalenecarboxylic acid, 4,4'-methylenebis [3-
hydroxy-, zinc salt.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 2-
Naphthalenecarboxylic acid, 4,4'-methylenebis [3-hydroxy-, zinc salt 
(P-99-1342; CAS No. 235083-88-2) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=10).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Record keeping requirements as specified in 
Sec.  721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
26. By adding new Sec.  721.5253 to subpart E to read as follows:


Sec.  721.5253  2-Naphthalenecarboxylic acid, 4,4'-methylenebis [3-
hydroxy-, strontium salt.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 2-
Naphthalenecarboxylic acid, 4,4'-methylenebis [3-hydroxy-, strontium 
salt (PMN P-99-1341; CAS No. 235083-90-6) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:

[[Page 70178]]

    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=10).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Record keeping requirements as specified in 
Sec.  721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
27. By adding new Sec.  721.5288 to subpart E to read as follows:


Sec.  721.5288  Chromate(2-), [3-hydroxy-4-[(2-hydroxy-1-
naphthenyl)azo]-7-nitro-1-substituted][N-[7-hydroxy-8-[(2-hydroxy-5-
nitrophenyl)azo]-1-substituted]-, salt (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
chromate(2-), [3-hydroxy-4-[(2-hydroxy-1-naphthenyl)azo]-7- nitro-1-
substituted][N-[7-hydroxy-8-[(2-hydroxy-5-nitrophenyl)azo]-1-
substituted]-, salt (PMN P-99-783) is subject to reporting under this 
section for the significant new use described in paragraph (a)(1) of 
this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
28. By adding new Sec.  721.5293 to subpart E to read as follows:


Sec.  721.5293  Poly(oxy-1,2-ethanediyl), alpha-(9Z)-9-
octadecenyl-.omega.-hydroxy-, phosphate, ammonium salt.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as poly(oxy-1,2-
ethanediyl), alpha-(9Z)-9-octadecenyl-.omega.-hydroxy-, phosphate, 
ammonium salt (PMN P-99-920; CAS No. 58857-49-1) is subject to 
reporting under this section for the significant new use described in 
paragraph (a)(1) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
29. By adding new Sec.  721.5315 to subpart E to read as follows:


Sec.  721.5315  Nickel, cobalt mixed metal oxide (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as nickel, 
cobalt mixed metal oxide. (PMN P-02-90) is subject to reporting under 
this section for the significant new use described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f) and (j).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to this section.

0
30. By adding new Sec.  721.5340 to subpart E to read as follows:


Sec.  721.5340  Substituted benzothiazole-azo-substituted 
benzoquinoline nickel complex (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substituted benzothiazole-azo-substituted benzoquinoline nickel complex 
(PMN P-99-897) is subject to reporting under this section for the 
significant new use described in paragraph (a)(1) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
31. By adding new Sec.  721.5358 to subpart E to read as follows:


Sec.  721.5358  2-propanol, 1,1',1'-nitrilotris-, compds. with ethanol 
2-[2-(C12-14- alkyloxy) ethoxy] derivs. hydrogen sulfates.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 2-propanol, 
1,1',1'-nitrilotris-, compds. with ethanol 2-[2-(C12-14- 
alkyloxy) ethoxy] derivs. hydrogen sulfates (PMN P-99-928; CAS No. 
222975-06-6) is subject to reporting under this section for the 
significant new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j) (surfactant used in toilet bowl 
cleaner).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of 721.185 apply to this section.

0
32. By adding new Sec.  721.5546 to subpart E to read as follows:


Sec.  721.5546  Halogen substituted oxetanes (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as 
halogen substituted oxetanes. (PMNs P-98-1033 through P-98-1035) are 
subject to reporting under

[[Page 70179]]

this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(q).
    (ii) Hazard communication program. A significant new use of these 
chemical substances is any manner or method of manufacture, import, or 
processing associated with any use of these chemical substances without 
providing risk notification as follows:
    (A) If as a result of the test data required under the TSCA section 
5(e) consent order for these chemical substances, the employer becomes 
aware that these chemical substances may present a risk of injury to 
human health or the environment, the employer must incorporate this new 
information, and any information on methods for protecting against such 
risk, into a Material Safety Data Sheet (MSDS) as described in Sec.  
721.72(c) within 90 days from the time the employer becomes aware of 
the new information. If this chemical substance is not being 
manufactured, imported, processed, or used in the employer's workplace, 
the employer must add the new information to an MSDS before the 
chemical substances are reintroduced into the workplace.
    (B) The employer must ensure that persons who will receive or who 
have received the chemical substances from the employer within 5 years 
from the date the employer becomes aware of the new information 
described in paragraph (a)(2)(i)(A) of this section, are provided an 
MSDS as described in Sec.  721.72(c) containing the information 
required under paragraph (a)(2)(i)(A) of this section within 90 days 
from the time the employer becomes aware of the new information.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), (f), (h), and (i) are applicable to 
manufacturers, importers, and processors of these chemical substances.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to this section.

0
33. By adding new Sec.  721.5560 to subpart E to read as follows:


Sec.  721.5560  Formaldehyde, polymer with (chloromethyl) oxirane and 
phenol, reaction products with 6H-dibenz[c,e][1,2]oxaphosphorin-6-
oxide.

    (a) Chemical substance and significant new uses subject to 
reporting. (1)The chemical substance identified as formaldehyde, 
polymer with (chloromethyl) oxirane and phenol, reaction products with 
6H-dibenz[c,e][1,2]oxaphosphorin-6-oxide. (PMN P-00-991; CAS No. 
300371-38-4) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=6).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
34. By adding new Sec.  721.5713 to subpart E to read as follows:


Sec.  721.5713  Phenol - biphenyl polymer condensate (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
phenol - biphenyl polymer condensate (PMN P-00-1220) is subject to 
reporting under this section for the significant new use described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified Sec.  721.90(a)(1), 
(b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
35. By adding new Sec.  721.5718 to subpart E to read as follows:


Sec.  721.5718  Phenol, 2,2'-[6-(2,4-dibutoxyphenyl)-1,3,5-triazine-
2,4-diyl]bis[5-butoxy-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as phenol, 2,2'-[6-
(2,4-dibutoxyphenyl)-1,3,5-triazine-2,4-diyl]bis[5-butoxy- (PMN P-01-
71; CAS No. 208343-47-9) is subject to reporting under this section for 
the significant new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified Sec.  721.90(a)(1), 
(b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
36. By adding new Sec.  721.5762 to subpart E to read as follows:


Sec.  721.5762  Aromatic aldehyde phenolic resin (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
aromatic aldehyde phenolic resin (PMN P-01-573) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1)
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in ' 
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of sect; 721.185 apply to this section.

0
37. By adding new Sec.  721.5905 to subpart E to read as follows:


Sec.  721.5905  Modified phenolic resin (generic).

    (a) Chemical substance and significant new uses subject to 
reporting.

[[Page 70180]]

(1) The chemical substance identified generically as a modified 
phenolic resin (PMN P-01-441) is subject to reporting under this 
section for the significant new use described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified Sec.  721.90(a)(1), 
(b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
38. By adding new Sec.  721.5908 to subpart E to read as follows:


Sec.  721.5908  Modified phenolic resin (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
modified phenolic resin (PMN P-01-561) is subject to reporting under 
this section for the significant new use described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified Sec.  721.90(a)(1), 
(b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
39. By adding new Sec.  721.5917 to subpart E to read as follows:


Sec.  721.5917  Phenyl azo dye (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
phenyl azo dye (PMN P-02-17) is subject to reporting under this section 
for the significant new use described in paragraph (a)(2) of this 
section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(v)(2), (w)(2), and (x)(2).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
40. By adding new Sec.  721.5935 to read as follows:


Sec.  721.5935  Alkylated nitroso-phenylenediamine (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
alkylated nitroso-phenylenediamine (PMN P-00-636) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (a)(3).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), (d), and (e) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
41. By adding new Sec.  721.6167 to subpart E to read as follows:


Sec.  721.6167  Piperdinium, 1,1-dimethyl-, chloride.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as piperdinium, 1,1-
dimethyl-, chloride. (PMN P-02-207; CAS No. 24307-26-4) is subject to 
reporting under this section for the significant new use described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), (i), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to this section.

0
42. By adding new Sec.  721.7250 to subpart E to read as follows:


Sec.  721.7250  Polyaziridinyl ester of an aliphatic alcohol (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
polyaziridinyl ester of an aliphatic alcohol (PMN P-01-97) is subject 
to reporting under this section for the significant new use described 
in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.575(b)(1) apply to this section.

0
43. By adding new Sec.  721.7255 to subpart E to read as follows:


Sec.  721.7255  Polyethyleneamine crosslinked with substituted 
polyethylene glycol (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
polyethyleneamine crosslinked with substituted polyethylene glycol with 
substituted polyethylene glycol (PMN P-01-833) is subject to reporting 
under this section

[[Page 70181]]

for the significant new use described in paragraph (a)(2) of this 
section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j) (absorbent polymer).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
44. By adding new Sec.  721.7270 to subpart E to read as follows:


Sec.  721.7270  1-propanaminium, 3-amino-, N, N, N-trimethyl-N-soya 
acyl derivs., chloride.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 1-propanaminium, 3-
amino-, N, N, N-trimethyl-N-soya acyl derivs., chloride (PMN P-01-646; 
CAS No. 391232-99-8) is subject to reporting under this section for the 
significant new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725 apply to this section.

0
45. By adding new Sec.  721.7290 to subpart E to read as follows:


Sec.  721.7290  Propanoic acid, 2-(trimethoxysilyl)-, ethyl ester.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as propanoic acid, 2-
(trimethoxysilyl)-, ethyl ester (PMN P-01-22; CAS No. 137787-41-8) is 
subject to reporting under this section for the significant new use 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified Sec.  721.90(a)(4), 
(b)(4), and (c)(4) (N=10).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
46. By adding new Sec.  721.8130 to subpart E to read as follows:


Sec.  721.8130  Propanamide, -(2-hydroxyethyl)-3-methoxy-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as propanamide, -(2-
hydroxyethyl)-3- methoxy- (PMN P-01-144; CAS No. 35544-45-7) is subject 
to reporting under this section for the significant new use described 
in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j) (organic stripper additive).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
47. By adding new Sec.  721.8140 to subpart E to read as follows:


Sec.  721.8140  Substituted propane (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
substituted propane (PMN P-01-298) is subject to reporting under this 
section for the significant new use described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j) (polymer additive).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
48. By adding new Sec.  721.8145 to subpart E to read as follows:


Sec.  721.8145  Propane,1,1,1,2,2,3,3-heptafluoro-3-methoxy-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 
propane,1,1,1,2,2,3,3-heptafluoro-3-methoxy- (PMN P-01-320; CAS No. 
375-03-1) is subject to reporting under this section for the 
significant new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified Sec.  721.80(j) (heating transfer fluid and a refrigerant) 
and (s) (100,000 kg)
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
49. By adding new Sec.  721.8340 to subpart E to read as follows:


Sec.  721.8340  Mono esters from 2- propenoic acid (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as mono 
esters from 2-propenoic acid (PMN P-01-85) is subject to reporting 
under this section for the significant new use described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:

[[Page 70182]]

    (i) Release to water. Requirements as specified Sec.  721.90(a)(1), 
(b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
50. By adding new Sec.  721.8485 to subpart E to read as follows:


Sec.  721.8485  2-Propenoic acid, 2-methyl-, (octahydro-4,7-methano-1H- 
indene-5-diyl)bis(methylene) ester.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 2-propenoic acid, 
2-methyl-, (octahydro-4,7-methano- 1H- indene-5-diyl)bis(methylene) 
ester (PMN P-99-1075; CAS No. 43048-08-4) is subject to reporting under 
this section for the significant new use described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f).
    (ii) Release to water. Requirements as specified in Sec.  
721.90(b)(1) and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), (i), and (k) are applicable to manufacturers, 
importers, and processors of these chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
51. By adding new Sec.  721.8940 to subpart E to read as follows:


Sec.  721.8940  Chromate(3-), bis[3-[[6-amino-1,4-dihydro-2-[[[4-[(2-
hydroxy-1-naphthalenyl)azo] phenyl]sulfonyl] amino]-4-(oxo-.kappa.O)-5- 
pyrimidinyl]azo-.kappaN1] -4-hydroxy-.kappa.O)-5-
nitrobenzenesulfonato(3-)]-, trisodium.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as chromate(3-), 
bis[3-[[6-amino-1,4-dihydro-2-[[[4-[(2-hydroxy-1-naphthalenyl)azo] 
phenyl] sulfonyl]amino]-4-(oxo-.kappa.O)-5-pyrimidinyl]azo-.kappaN1] -
4-hydroxy-.kappa.O)-5-nitrobenzenesulfonato(3-)]-, trisodium (PMN P-01-
459; CAS No. 178452-72-7) is subject to reporting under this section 
for the significant new use described in paragraph (a)(2) of this 
section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (v)(1), (w)(1), and (x)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
52. By adding new Sec.  721.8950 to subpart E to read as follows:


Sec.  721.8950  Chromate(3-), bis[3-[[6-amino-1,4-dihydro-2-[[[4-[(2-
hydroxy-1-naphthalenyl)azo]phenyl]sulfonyl]amino]-4-(oxo-.kappa.O)-5-
pyrimidinyl]azo-.kappaN1]-4-hydroxy-.kappa.O)-5-
nitrobenzenesulfonato(3-)]-, sodium triethanolamine salts.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as chromate(3-), 
bis[3-[[6-amino-1,4-dihydro-2- [[[4-[(2-hydroxy-1-naphthalenyl)azo] 
phenyl]sulfonyl]amino]-4-(oxo-.kappa.O)-5-pyrimidinyl]azo-.kappaN1] -4-
hydroxy-.kappa.O)-5-nitrobenzenesulfonato(3-)]-, sodium triethanolamine 
salts. (PMN P-01-460; CAS No. 327177-98-0) is subject to reporting 
under this section for the significant new use described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (v)(1), (w)(1), and (x)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
53. By adding new Sec.  721.9078 to subpart E to read as follows:


Sec.  721.9078  6-Methoxy-1H-benz[de]isoquinoline-2 [3H]-dione 
derivative (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 6-
methoxy-1H-benz[de]isoquinoline-2 [3H]-dione derivative (PMN P-00-1205) 
is subject to reporting under this section for the significant new use 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=30).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
54. By adding new Sec.  721.9079 to subpart E to read as follows:


Sec.  721.9079  Dihydro quinacridone derivative (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as dihydro 
quinacridone derivative (PMN P-01-397) is subject to reporting under 
this section for the significant new use described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(s) (1,000 kg).
    (ii) Release to water. Requirements as specified Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=2).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), (i), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The

[[Page 70183]]

provisions of Sec.  721.185 apply to this section.

0
55. By adding new Sec.  721.9501 to subpart E to read as follows:


Sec.  721.9501  Silane, triethoxy[3-oxiranylmethoxy)propyl]-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as silane, 
triethoxy[3-oxiranylmethoxy)propyl]- (PMN P-01-781; CAS No. 2602-34-2) 
is subject to reporting under this section for the significant new use 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(y)(l).
    (ii) Release to water. Requirements as specified Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=10).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), (i), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
56. By adding new Sec.  721.9506 to subpart E to read as follows:


Sec.  721.9506  Halogenated arylsilane (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
halogenated arylsilane (PMN P-01-9) is subject to reporting under this 
section for the significant new use described in paragraph (a)(1) of 
this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified Sec.  721.90(a)(1), 
(b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
57. By adding new Sec.  721.9511 to subpart E to read as follows:


Sec.  721.9511  Silicic acid 
(H6SiO2O7), magnesium, strontium 
salt(1:1:2), dysprosium and europium-doped.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as silicic acid 
(H6SiO2O7) magnesium, strontium 
salt(1:1:2), dysprosium and europium-doped. (PMN P-98-848; CAS 
No.181828-07-9) is subject to reporting under this section for the 
significant new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j) (manufacture or import of the chemical 
substance where greater than 5% of the chemical substance is below the 
10 micron (respirable particles) threshold).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
58. By adding new Sec.  721.9572 to subpart E to read as follows:


Sec.  721.9572  Substituted alkyl sulfonamide (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substituted alkyl sulfonamide (PMN P-00-838) is subject to reporting 
under this section for the significant new use described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
59. By adding new Sec.  721.9640 to subpart E to read as follows:


Sec.  721.9640  Salt of an acrylic acid - acrylamide terpolymer 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as salt of 
an acrylic acid - acrylamide terpolymer (PMN P-99-817) is subject to 
reporting under this section for the significant new use described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(v)(2), (w)(2), and (x)(2).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
60. By adding new Sec.  721.9674 to subpart E to read as follows:


Sec.  721.9674  Sulfonated-copper phthalocyanine salt of a 
triarylmethane dye (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
sulfonated-copper phthalocyanine salt of a triarylmethane dye (PMN P-
00-1055) is subject to reporting under this section for the significant 
new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(v)(1), (w)(1), and (x)(1).
    (ii) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), (i), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The

[[Page 70184]]

provisions of Sec.  721.185 apply to this section.

0
61. By adding new Sec.  721.9929 to subpart E to read as follows:


Sec.  721.9929  Polyurea (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
polyurea (PMN P-01-716) is subject to reporting under this section for 
the significant new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified Sec.  721.90(a)(1), 
(b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
62. By adding new Sec.  721.9959 to subpart E to read as follows:


Sec.  721.9959  Polyurethane polymer (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
polyurethane polymer (PMN P-01-481) is subject to reporting under this 
section for the significant new use described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this chemical substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to this section.

[FR Doc. 03-31121 Filed 12-16-03; 8:45 am]

BILLING CODE 6560-50-S
      

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